Q0IAI2 · Q0IAI2_SYNS3
- ProteinMethionine--tRNA ligase
- GenemetG
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids514 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
Catalytic activity
- tRNA(Met) + L-methionine + ATP = L-methionyl-tRNA(Met) + AMP + diphosphate
Cofactor
Note: Binds 1 zinc ion per subunit.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 125 | Zn2+ (UniProtKB | ChEBI) | |||
Binding site | 128 | Zn2+ (UniProtKB | ChEBI) | |||
Binding site | 143 | Zn2+ (UniProtKB | ChEBI) | |||
Binding site | 146 | Zn2+ (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | ATP binding | |
Molecular Function | metal ion binding | |
Molecular Function | methionine-tRNA ligase activity | |
Biological Process | methionyl-tRNA aminoacylation |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameMethionine--tRNA ligase
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Cyanobacteriota > Cyanophyceae > Synechococcales > Synechococcaceae > Synechococcus
Accessions
- Primary accessionQ0IAI2
Proteomes
Subcellular Location
Interaction
Structure
Family & Domains
Features
Showing features for motif, domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Motif | 10-20 | 'HIGH' region | |||
Domain | 134-360 | Methionyl/Leucyl tRNA synthetase | |||
Motif | 297-301 | 'KMSKS' region | |||
Domain | 375-510 | Methionyl-tRNA synthetase anticodon-binding | |||
Sequence similarities
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length514
- Mass (Da)57,884
- Last updated2006-10-03 v1
- ChecksumED92C487C983ACAE
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP000435 EMBL· GenBank· DDBJ | ABI45967.1 EMBL· GenBank· DDBJ | Genomic DNA |