Q0I6L2 · Q0I6L2_SYNS3
- ProteinRibonuclease H
- GenernhA
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids250 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
Catalytic activity
Cofactor
Note: Binds 1 Mg2+ ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | magnesium ion binding | |
Molecular Function | nucleic acid binding | |
Molecular Function | RNA-DNA hybrid ribonuclease activity | |
Biological Process | DNA replication, removal of RNA primer |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameRibonuclease H
- EC number
- Short namesRNase H
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Cyanobacteriota > Cyanophyceae > Synechococcales > Synechococcaceae > Synechococcus
Accessions
- Primary accessionQ0I6L2
Proteomes
Subcellular Location
Interaction
Structure
Family & Domains
Features
Showing features for domain, region.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 8-152 | RNase H type-1 | ||||
Sequence: RGRVVAAATDGACSGNPGPGGWGALIRFEDGSVEEFGGADPATTNNRMELQAALATLQRLAELPLHPNLTLRTDSKYLIDGLGSWMAGWKRKGWRTAAGKPVLNQDLWQALDQARLAEVPLSYVKGHSGDPDNDRVDQIAVAYSK | ||||||
Region | 153-174 | Disordered | ||||
Sequence: GRKQTPPSLASPSAAPPQPLVD |
Sequence similarities
Belongs to the RNase H family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length250
- Mass (Da)27,229
- Last updated2006-10-03 v1
- ChecksumB489356E1D1C260E
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP000435 EMBL· GenBank· DDBJ | ABI47397.1 EMBL· GenBank· DDBJ | Genomic DNA |