Q0H2I1 · Q0H2I1_DICVI

Function

function

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.

Catalytic activity

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentmitochondrial inner membrane
Molecular FunctionNADH dehydrogenase (ubiquinone) activity
Molecular FunctionNADH dehydrogenase activity
Biological ProcessATP synthesis coupled electron transport
Biological Processelectron transport coupled proton transport

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    NADH-ubiquinone oxidoreductase chain 5
  • EC number
  • Alternative names
    • NADH dehydrogenase subunit 5

Gene names

    • Name
      nad5

Encoded on

  • Mitochondrion

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Nematoda > Chromadorea > Rhabditida > Rhabditina > Rhabditomorpha > Strongyloidea > Metastrongylidae > Dictyocaulus

Accessions

  • Primary accession
    Q0H2I1

Subcellular Location

Membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane23-42Helical
Transmembrane63-83Helical
Transmembrane89-110Helical

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain23-131NADH:quinone oxidoreductase/Mrp antiporter membrane subunit

Keywords

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    132
  • Mass (Da)
    14,944
  • Last updated
    2006-10-03 v1
  • Checksum
    ECD3B059508F19ED
GDFFLFVFLGGSFFVNLFMDVEIYFYFFMCYFLLFGSFTKSAQFPFSGWLPKAMSAPTPVSSLVHSSTLVTAGLILLMGYEVLLFNVVLLRLMFFFGLLTMFFSSILALLEEDMKKVVALSTLSQLGFMMLS

Features

Showing features for non-terminal residue.

TypeIDPosition(s)Description
Non-terminal residue1
Non-terminal residue132

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
DQ299707
EMBL· GenBank· DDBJ
ABC24872.1
EMBL· GenBank· DDBJ
Genomic DNA
DQ299708
EMBL· GenBank· DDBJ
ABC24873.1
EMBL· GenBank· DDBJ
Genomic DNA
DQ299709
EMBL· GenBank· DDBJ
ABC24874.1
EMBL· GenBank· DDBJ
Genomic DNA
DQ299710
EMBL· GenBank· DDBJ
ABC24875.1
EMBL· GenBank· DDBJ
Genomic DNA
DQ299711
EMBL· GenBank· DDBJ
ABC24876.1
EMBL· GenBank· DDBJ
Genomic DNA
DQ299712
EMBL· GenBank· DDBJ
ABC24877.1
EMBL· GenBank· DDBJ
Genomic DNA
DQ299713
EMBL· GenBank· DDBJ
ABC24878.1
EMBL· GenBank· DDBJ
Genomic DNA
DQ299714
EMBL· GenBank· DDBJ
ABC24879.1
EMBL· GenBank· DDBJ
Genomic DNA
DQ299731
EMBL· GenBank· DDBJ
ABC24896.1
EMBL· GenBank· DDBJ
Genomic DNA
DQ299737
EMBL· GenBank· DDBJ
ABC24902.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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