Q0DJC5 · OST1A_ORYSJ

  • Protein
    Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1A
  • Gene
    OST1A
  • Status
    UniProtKB reviewed (Swiss-Prot)
  • Amino acids
  • Protein existence
    Evidence at transcript level
  • Annotation score
    3/5

Function

function

Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc3Man9GlcNAc2 in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

Pathway

Protein modification; protein glycosylation.

GO annotations

all annotationsall molecular functionnucleotide bindingmolecular_functionnucleic acid bindingdna bindingchromatin bindingdna-binding transcription factor activityrna bindingcytoskeletal motor activitycatalytic activitynuclease activitysignaling receptor bindingstructural molecule activitytransporter activitybindingprotein bindingtranslation factor activity, rna bindinglipid bindingkinase activitytransferase activityhydrolase activityoxygen bindingenzyme regulator activitycarbohydrate bindingsignaling receptor activitytranslation regulator activitytranscription regulator activityother molecular functionall biological processcarbohydrate metabolic processgeneration of precursor metabolites and energynucleobase-containing compound metabolic processdna metabolic processtranslationlipid metabolic processtransportresponse to stresscell cyclecell communicationsignal transductioncell-cell signalingmulticellular organism developmentcircadian rhythmbiological_processmetabolic processcatabolic processbiosynthetic processresponse to light stimulusresponse to external stimulustropismresponse to biotic stimulusresponse to abiotic stimulusresponse to endogenous stimulusembryo developmentpost-embryonic developmentfruit ripeningabscissionpollinationflower developmentcellular processprogrammed cell deathphotosynthesiscellular component organizationcell growthprotein metabolic processcellular homeostasissecondary metabolic processreproductive processcell differentiationprotein modification processgrowthepigenetic regulation of gene expressionresponse to chemicalanatomical structure developmentregulation of molecular functionother biological processall cellular componentcellular_componentextracellular regioncell wallintracellular anatomical structurenucleusnuclear envelopenucleoplasmnucleoluscytoplasmmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuscytosolribosomecytoskeletonplasma membranechloroplastplastidthylakoidmembraneexternal encapsulating structureother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentoligosaccharyltransferase complex
Biological Processprotein N-linked glycosylation via asparagine

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1A
  • Alternative names
    • Ribophorin IA (RPN-IA)
    • Ribophorin-1A

Gene names

    • Name
      OST1A
    • Synonyms
      RPN1A
    • ORF names
      OsJ_17960
    • Ordered locus names
      Os05g0301500, LOC_Os05g23600

Organism names

  • Taxonomic identifier
  • Strain
    • cv. Nipponbare
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > Liliopsida > Poales > Poaceae > BOP clade > Oryzoideae > Oryzeae > Oryzinae > Oryza > Oryza sativa

Accessions

  • Primary accession
    Q0DJC5
  • Secondary accessions
    • A0A0P0WKA7

Proteomes

Genome annotation databases

Subcellular Location

Endoplasmic reticulum membrane
; Single-pass type I membrane protein

Features

Showing features for topological domain, transmembrane.

TypeIDPosition(s)Description
Topological domain29-437Lumenal
Transmembrane438-455Helical
Topological domain456-615Cytoplasmic

Keywords

PTM/Processing

Features

Showing features for signal, chain, modified residue, glycosylation.

TypeIDPosition(s)Description
Signal1-28
ChainPRO_000042080929-615Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1A
Modified residue187N6-acetyllysine
Glycosylation300N-linked (GlcNAc...) asparagine
Glycosylation353N-linked (GlcNAc...) asparagine
Glycosylation431N-linked (GlcNAc...) asparagine

Keywords

Proteomic databases

PTM databases

Expression

Gene expression databases

Interaction

Subunit

Component of the oligosaccharyltransferase (OST) complex.

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the OST1 family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Sequence processing
    The displayed sequence is further processed into a mature form.
  • Length
    615
  • Mass (Da)
    69,522
  • Last updated
    2006-10-17 v1
  • Checksum
    B5248D361070F22B
MATPPPLRRVAALLLLLVAAASTPTARADLVVTRADRKVDLTSHIVRVLTSLKVENSGPEAVSQFLLAFPNVQAKNLAAIRAFGTEEKVKGPSMVLPIEVVQPSGVPPELTFFSASLSKPLEKGKTLHLDVLTVFTHSVQPFPEEITQAESQLVVYQDSAQYLSPYPVKVQTLSIRLPGGRVESYTKYPNTKLAESELKYGPYEDLPPFSYSPMVVHYENNNPFAVAKEVIREIEISHWGNVQITEHYNIAHGGAKLKGEFSRIDYQSRPYIRGVSSFRHLIARLPPRAHSIYYRDEIGNISTSHLWSDSKKTQLEVEPRFPLFGGWQTTFTIGYGLPLQDFVFNSDGKRFLNITFGSPVEEILIEKLIVKVVLPEGSKDIDISVPFPTKQEQEVKYSHLDISGRPVVVLEKLDVIPEHNLYFQVYYRFNNISLLREPMMLITGFFLLFMACIVYMRTDMSISKNSPSYLAKVQWDEVQSIIQQIQAIFNQCLAAHDKLETSLHELSRSGDVKSCKVARKTADAQFKELAKELKPLLTSLQSSSQSYQIWPKVEELVAKERELQDKLMTRHSTVVDSFEKKLRGQDVENRIAAQQQKVAALRQEVESLLEYISEI

Computationally mapped potential isoform sequences

There are 2 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A0A0P0WKA3A0A0P0WKA3_ORYSJOs05g0301500211
A0A0P0WKC1A0A0P0WKC1_ORYSJOs05g0301500352

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AP008211
EMBL· GenBank· DDBJ
BAF17048.1
EMBL· GenBank· DDBJ
Genomic DNA
AP014961
EMBL· GenBank· DDBJ
BAS93226.1
EMBL· GenBank· DDBJ
Genomic DNA
CM000142
EMBL· GenBank· DDBJ
EEE63151.1
EMBL· GenBank· DDBJ
Genomic DNA
AK070329
EMBL· GenBank· DDBJ
BAG91888.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

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