Q0CMB0 · ROK1_ASPTN

Function

function

ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis. Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA.

Catalytic activity

Features

Showing features for binding site.

1749100200300400500600700
TypeIDPosition(s)Description
Binding site254-261ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentnucleolus
Molecular FunctionATP binding
Molecular FunctionATP hydrolysis activity
Molecular FunctionRNA binding
Molecular FunctionRNA helicase activity
Biological Processmaturation of SSU-rRNA

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    ATP-dependent RNA helicase rok1
  • EC number

Gene names

    • Name
      rok1
    • ORF names
      ATEG_05174

Organism names

Accessions

  • Primary accession
    Q0CMB0

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00002827011-749ATP-dependent RNA helicase rok1

Interaction

Subunit

Interacts with the U3 snoRNA and is associated with the 90S and 40S pre-ribosomes.

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for region, compositional bias, motif, domain.

Type
IDPosition(s)Description
Region1-121Disordered
Compositional bias8-39Polar residues
Compositional bias100-121Basic and acidic residues
Region148-182Disordered
Compositional bias167-182Basic and acidic residues
Motif192-224Q motif
Domain241-457Helicase ATP-binding
Region324-366Disordered
Compositional bias333-352Acidic residues
Motif404-407DEAD box
Domain497-665Helicase C-terminal
Compositional bias672-720Basic and acidic residues
Region672-749Disordered
Compositional bias724-741Polar residues

Domain

The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    749
  • Mass (Da)
    82,178
  • Last updated
    2007-04-03 v2
  • Checksum
    01A90298CADEEC0C
MDAFKLLTRSTNLKTGRAAATSAAQTSRLPSTGKAANPQLFHNSEADRLLEEKKKHGQKRKRGHGADDAGSEDEDAADLDFFSSAKRASTGGAVAGKRHQEQASADKDGDSGSEDGSEMDEVQRRTVLNAHKIKVTDLRDLDQIQSTNAQTLQTEEPKKKKKKKAKAQQEEPKTLTKKEQKKARRLFPQPLVSFKELRTKYKISRRLAENIAEQGFTVPTEVQLGTLPLQLGDSSVQQASKPGETVEPDLLVVAPTGSGKTLSFLIPVINKIVRHHHEQPDERGIFAVVVAPTKELASQIVNEGRKLVQGTGVKITLMKKGMQVVERDGDGDSDEKDVLDEDSADSGSDSEDDEQTTDKKTKGKAPVTKSDILVTTPLLLVNALSANRTKPLAALPLVRNIVLDEADVLLDPLFREQTLDIWRSCTHPELRASLWSATMGSNVEDLAKSTIQERKDLSGTTKSYPLIRLVVGLKDSAIPNIQHKLVYAATEQGKLLGLRQLLHPTARTATDVHLRPPFLIFTQTIPRAVALHSELLYDIPPEAGGSSRIAVLHSELSDSQRSEIMKGFRKGEIWILVTTDLLARGVDFRGINGVVNYDIPNSAAVYVHRVGRTGRAGREGGVAVTYYTKEDIPYVKSIANIIDVSEKLRGAGGEKSVQKWLLDSLPDLSKKDKKELKKHGVKARQSNLKSIKDNKEFRQAKISTKSGYERRMENKKKGAIAASRNRKSQPQAPSTGADSGDDSWSGLED

Sequence caution

The sequence EAU34243.1 differs from that shown. Reason: Erroneous gene model prediction

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias8-39Polar residues
Compositional bias100-121Basic and acidic residues
Compositional bias167-182Basic and acidic residues
Compositional bias333-352Acidic residues
Compositional bias672-720Basic and acidic residues
Compositional bias724-741Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CH476600
EMBL· GenBank· DDBJ
EAU34243.1
EMBL· GenBank· DDBJ
Genomic DNA Sequence problems.

Genome annotation databases

Similar Proteins

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