Q0CCL1 · RSP5_ASPTN
- ProteinProbable E3 ubiquitin-protein ligase hulA
- GenehulA
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids808 (go to sequence)
- Protein existenceInferred from homology
- Annotation score5/5
Function
function
E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Probably involved in the regulatory network controlling carbon source utilization.
Catalytic activity
Pathway
Protein modification; protein ubiquitination.
Features
Showing features for active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Active site | 776 | Glycyl thioester intermediate | ||||
Sequence: C |
GO annotations
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameProbable E3 ubiquitin-protein ligase hulA
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Eurotiomycetes > Eurotiomycetidae > Eurotiales > Aspergillaceae > Aspergillus > Aspergillus subgen. Circumdati
Accessions
- Primary accessionQ0CCL1
Proteomes
Organism-specific databases
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000395709 | 1-808 | Probable E3 ubiquitin-protein ligase hulA | |||
Sequence: MGSNLPAQPNLRVTIIAADGLYKRDVFRFPDPFAVATVGGEQTHTTSVIKKTLNPYWNEMFDLRVNEDSILAIQIFDQKKFKKKDQGFLGVINVRIGDVIDLQMGGDEMLTRDLKKSNDNLVVHGKLIINLSTNLSTPNTNQANGLHRSNLQSSTSSGLVPQVTAPHASPGPSQLDPTASNPSLNPQRVPSTTRPSSTVAPVNGAAAPGASRTNLSSFEDSQGRLPAGWERREDNLGRTYYVDHNTRTTTWTRPSSNYNEATQRTQREANMQLERRAHQSRMLPEDRTGASSPNLQENQQAQTPPAGGSANAVSMMATGATTAGTGELPPGWEQRTTPEGRPYFVDHNTRTTTWVDPRRQQYIRMYGQNANGNNTTIQQQPVSQLGPLPSGWEMRLTNTARVYFVDHNTKTTTWDDPRLPSSLDQGVPQYKRDFRRKLIYFRSQPALRIMSGQCHVKVRRNNIFEDSYAEIMRQSASDLKKRLMIKFDGEDGLDYGGLSREFFFLLSHEMFNPFYCLFEYSAHDNYTLQINPHSGVNPEHLNYFKFIGRVVGLAIFHRRFLDSFFIGAFYKMMLRKKVSLQDMEGVDEDLHRNLTWTLDNDIEGIIELTFAVDDEKFGERRTIDLKPGGRDIPVTNENKHEYVELVTEWKIVKRVEEQFNAFMSGFNELIPADLVNVFDERELELLIGGIADIDVDDWKKHTDYRGYQEQDEVIQNFWKIVRTWDAEQKSRLLQFTTGTSRIPVNGFKDLQGSDGPRRFTIEKSGDPAALPKSHTCFNRLDLPPYKTHETLEHKLSIAVEETLGFGQE |
Interaction
Structure
Family & Domains
Features
Showing features for domain, compositional bias, region.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 1-112 | C2 | ||||
Sequence: MGSNLPAQPNLRVTIIAADGLYKRDVFRFPDPFAVATVGGEQTHTTSVIKKTLNPYWNEMFDLRVNEDSILAIQIFDQKKFKKKDQGFLGVINVRIGDVIDLQMGGDEMLTR | ||||||
Compositional bias | 134-200 | Polar residues | ||||
Sequence: NLSTPNTNQANGLHRSNLQSSTSSGLVPQVTAPHASPGPSQLDPTASNPSLNPQRVPSTTRPSSTVA | ||||||
Region | 134-231 | Disordered | ||||
Sequence: NLSTPNTNQANGLHRSNLQSSTSSGLVPQVTAPHASPGPSQLDPTASNPSLNPQRVPSTTRPSSTVAPVNGAAAPGASRTNLSSFEDSQGRLPAGWER | ||||||
Domain | 223-256 | WW 1 | ||||
Sequence: GRLPAGWERREDNLGRTYYVDHNTRTTTWTRPSS | ||||||
Region | 275-346 | Disordered | ||||
Sequence: RRAHQSRMLPEDRTGASSPNLQENQQAQTPPAGGSANAVSMMATGATTAGTGELPPGWEQRTTPEGRPYFVD | ||||||
Compositional bias | 285-321 | Polar residues | ||||
Sequence: EDRTGASSPNLQENQQAQTPPAGGSANAVSMMATGAT | ||||||
Domain | 326-359 | WW 2 | ||||
Sequence: GELPPGWEQRTTPEGRPYFVDHNTRTTTWVDPRR | ||||||
Domain | 386-419 | WW 3 | ||||
Sequence: GPLPSGWEMRLTNTARVYFVDHNTKTTTWDDPRL | ||||||
Domain | 475-808 | HECT | ||||
Sequence: SASDLKKRLMIKFDGEDGLDYGGLSREFFFLLSHEMFNPFYCLFEYSAHDNYTLQINPHSGVNPEHLNYFKFIGRVVGLAIFHRRFLDSFFIGAFYKMMLRKKVSLQDMEGVDEDLHRNLTWTLDNDIEGIIELTFAVDDEKFGERRTIDLKPGGRDIPVTNENKHEYVELVTEWKIVKRVEEQFNAFMSGFNELIPADLVNVFDERELELLIGGIADIDVDDWKKHTDYRGYQEQDEVIQNFWKIVRTWDAEQKSRLLQFTTGTSRIPVNGFKDLQGSDGPRRFTIEKSGDPAALPKSHTCFNRLDLPPYKTHETLEHKLSIAVEETLGFGQE |
Sequence similarities
Belongs to the RSP5/NEDD4 family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length808
- Mass (Da)91,724
- Last updated2006-10-17 v1
- ChecksumDC5C588FFF81C17D
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 134-200 | Polar residues | ||||
Sequence: NLSTPNTNQANGLHRSNLQSSTSSGLVPQVTAPHASPGPSQLDPTASNPSLNPQRVPSTTRPSSTVA | ||||||
Compositional bias | 285-321 | Polar residues | ||||
Sequence: EDRTGASSPNLQENQQAQTPPAGGSANAVSMMATGAT |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CH476606 EMBL· GenBank· DDBJ | EAU30705.1 EMBL· GenBank· DDBJ | Genomic DNA |