Q0AD61 · RISB_NITEC

Function

function

Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

Catalytic activity

Pathway

Cofactor biosynthesis; riboflavin biosynthesis; riboflavin from 2-hydroxy-3-oxobutyl phosphate and 5-amino-6-(D-ribitylamino)uracil: step 1/2.

Features

Showing features for binding site, active site.

116520406080100120140160
TypeIDPosition(s)Description
Binding site285-amino-6-(D-ribitylamino)uracil (UniProtKB | ChEBI)
Binding site62-645-amino-6-(D-ribitylamino)uracil (UniProtKB | ChEBI)
Binding site86-885-amino-6-(D-ribitylamino)uracil (UniProtKB | ChEBI)
Binding site91-92(2S)-2-hydroxy-3-oxobutyl phosphate (UniProtKB | ChEBI)
Active site94Proton donor
Binding site1195-amino-6-(D-ribitylamino)uracil (UniProtKB | ChEBI)
Binding site133(2S)-2-hydroxy-3-oxobutyl phosphate (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentriboflavin synthase complex
Molecular Function6,7-dimethyl-8-ribityllumazine synthase activity
Biological Processriboflavin biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    6,7-dimethyl-8-ribityllumazine synthase
  • EC number
  • Short names
    DMRL synthase
    ; LS
    ; Lumazine synthase

Gene names

    • Name
      ribH
    • Ordered locus names
      Neut_2517

Organism names

Accessions

  • Primary accession
    Q0AD61

Proteomes

Subcellular Location

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_10000404631-1656,7-dimethyl-8-ribityllumazine synthase

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the DMRL synthase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    165
  • Mass (Da)
    17,463
  • Last updated
    2006-10-17 v1
  • Checksum
    E38FC54142E749F1
MSYYDNILEIDSDLNGNGLCIGIVMSRFNIDTSEGLLGACTTELAKLGVQEADIVLVTVPGALEIPLALQKLAISDRYDALIALGAVIHGETYHFDVVANESARGLIAVGLEYDIPIANGILTTDNEDQATARMTEKGAETARVAVEMANLALTLGEMDQSTTSS

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP000450
EMBL· GenBank· DDBJ
ABI60721.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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