Q09HU1 · Q09HU1_ACASC

Function

function

Cytochromes P450 are a group of heme-thiolate monooxygenases. They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.

Catalytic activity

Cofactor

heme (UniProtKB | Rhea| CHEBI:30413 )

Features

Showing features for binding site.

151850100150200250300350400450500
TypeIDPosition(s)Description
Binding site462Fe (UniProtKB | ChEBI) of heme (UniProtKB | ChEBI); axial binding residue

GO annotations

AspectTerm
Cellular Componentendoplasmic reticulum membrane
Molecular Functionaromatase activity
Molecular Functionheme binding
Molecular Functioniron ion binding
Molecular Functionsteroid 17-alpha-monooxygenase activity
Biological Processhormone biosynthetic process
Biological Processprogesterone metabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Cytochrome P450 1A
  • EC number

Gene names

    • Name
      CYP1A1

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Neoteleostei > Acanthomorphata > Eupercaria > Spariformes > Sparidae > Acanthopagrus

Accessions

  • Primary accession
    Q09HU1

Subcellular Location

Endoplasmic reticulum membrane
; Peripheral membrane protein
Microsome membrane
; Peripheral membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane12-33Helical

Keywords

Family & Domains

Sequence similarities

Belongs to the cytochrome P450 family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    518
  • Mass (Da)
    58,841
  • Last updated
    2006-10-17 v1
  • Checksum
    8F6383C96C295540
MVLILPFIGPVSVSEGLVAMITMCLVYMILKFFRTEIPEGLRQLPGPKPLPIIGNVLEVGRNPYLSLTAMSKRYGDVFQIQIGMRPVVVLSGSETVRQALIKQGEELAGRPDLYSFRFINDGKSLAFSTDQAGVWRARRKLAYSALRSFATLEGTTPEYSCALEEHVSKEAEYLVKQFNTVMETDGSFDPFRHIVVSVANVICGMCFGRRYDHNNQELLNLVNLSDEFGQVVASGNPADFIPILQYLPSTAMKKFLNINDRFNAFVQKIVSEHYTTFDKDNIRDITDSLIDHCEDRKLDEDSNVQMSDEKIVGIVNDLFGAGFDTISTALSWSVMYLVAYPEIQERLHQEIKETVGLDRTPCLSDRPNLPFLEAFILEIFRHSSFLPFTIPHCSTKDTSLNGYFIPKDTCVFINQWQINHDPELWKDPSFFNPDRFLNADGTEVNRLEGEKMMVFGMGKRRCIGEVIARHEVFLFLAVLVQNLQFHAMPGEPLDMTPEYGLTMKHKRCHLRAAMRRGT

Features

Showing features for non-terminal residue.

TypeIDPosition(s)Description
Non-terminal residue518

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
DQ898145
EMBL· GenBank· DDBJ
ABI54450.1
EMBL· GenBank· DDBJ
mRNA

Similar Proteins

Disclaimer

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