Q09995 · Q09995_CAEEL

Function

function

Polymerase that creates the 3'-poly(A) tail of mRNA's.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Note: Binds 2 magnesium ions. Also active with manganese.
Mn2+ (UniProtKB | Rhea| CHEBI:29035 )

Features

Showing features for binding site.

155450100150200250300350400450500550
TypeIDPosition(s)Description
Binding site93-95ATP (UniProtKB | ChEBI)
Binding site106Mg2+ 2 (UniProtKB | ChEBI); catalytic
Binding site106Mg2+ 1 (UniProtKB | ChEBI); catalytic
Binding site106-108ATP (UniProtKB | ChEBI)
Binding site108Mg2+ 2 (UniProtKB | ChEBI); catalytic
Binding site108Mg2+ 1 (UniProtKB | ChEBI); catalytic
Binding site160ATP (UniProtKB | ChEBI)
Binding site160Mg2+ 2 (UniProtKB | ChEBI); catalytic
Binding site221ATP (UniProtKB | ChEBI)
Binding site230ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentnucleus
Molecular FunctionATP binding
Molecular Functionmetal ion binding
Molecular Functionpoly(A) RNA polymerase activity
Molecular FunctionRNA binding
Biological ProcessmRNA processing
Biological ProcessRNA 3'-end processing

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Poly(A) polymerase
  • EC number

Gene names

    • Name
      pap-2
    • ORF names
      CELE_T15H9.6
      , T15H9.6

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • Bristol N2
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Nematoda > Chromadorea > Rhabditida > Rhabditina > Rhabditomorpha > Rhabditoidea > Rhabditidae > Peloderinae > Caenorhabditis

Accessions

  • Primary accession
    Q09995

Proteomes

Organism-specific databases

Subcellular Location

Keywords

  • Cellular component

PTM/Processing

Expression

Gene expression databases

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain15-207Poly(A) polymerase nucleotidyltransferase
Domain212-361Poly(A) polymerase central
Domain364-425Poly(A) polymerase RNA-binding

Sequence similarities

Belongs to the poly(A) polymerase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    554
  • Mass (Da)
    63,008
  • Last updated
    1996-11-01 v1
  • Checksum
    92573DD4DEF9BE82
MQSVNNATSSTPIFGVSQPISTAFPKANDVALTSSLQSSLEEFKSFESKQETLLRIKVLKNLDGLVKDWVQKTTISRIPKDQMFNAGGKLIPFGSYRLGVHSSGADIDSIVVAPRHITRSDFFNSFKDILAKNPEVTELCAVEKAFVPIMTLKYSGVDIDILFARLALKSVPEDLNILDDSLLKNLDEESVRSLNGCRVAEQLLKLVPHQKNFCITLRAIKLWAKNHGIYSNSMGFFGGITWAILVARICQLYPNAAPSRLIQKVFFIFSTWNWPAPVLLDYINCDRTDLAQLNQLVWDPRRNHADRYHLMPIITPAFPQQNSTHNVSRSSMKVIQDEMKKALIICDKIHEGTLEWRDLLEEINFFSKYHHFIALKLKAESVKEELAFGGFFESRIRQLVQILEKNQVIQVAQINPRKFKDVKDPKKSIWFIGLEFVANVKNVDLTSDIQQFKMNIDRQSMSVKEIAAGCQVETDFTYEKRSNLINIISKKDLSCQRIMKKTEVSVPVTKDSRNLKRHILDEAPTVQKKHKLDVLEKSTVDSLLSTLKKNTSHA

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
BX284602
EMBL· GenBank· DDBJ
CAA87419.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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