Q09477 · DPFF1_CAEEL

  • Protein
    Zinc finger protein dpff-1
  • Gene
    dpff-1
  • Status
    UniProtKB reviewed (Swiss-Prot)
  • Amino acids
  • Protein existence
    Evidence at transcript level
  • Annotation score
    5/5

Function

function

Probable transcription factor, involved in meiosis and stress protection.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytoplasm
Cellular ComponentnBAF complex
Cellular Componentnucleus
Molecular Functionmetal ion binding
Biological Processapoptotic process
Biological Processchromatin remodeling
Biological Processmeiotic cell cycle
Biological Processnervous system development
Biological Processpositive regulation of double-strand break repair
Biological Processregulation of G1/S transition of mitotic cell cycle
Biological Processregulation of mitotic metaphase/anaphase transition
Biological Processregulation of nucleotide-excision repair
Biological Processresponse to heat

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Zinc finger protein dpff-1

Gene names

    • Name
      dpff-1
    • ORF names
      C28H8.9

Organism names

  • Taxonomic identifier
  • Strain
    • Bristol N2
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Nematoda > Chromadorea > Rhabditida > Rhabditina > Rhabditomorpha > Rhabditoidea > Rhabditidae > Peloderinae > Caenorhabditis

Accessions

  • Primary accession
    Q09477
  • Secondary accessions
    • A8WFG1
    • H2KZ28
    • Q09247

Proteomes

Organism-specific databases

Subcellular Location

Nucleus
Cytoplasm
Note: Expressed at higher level in nuclei.

Keywords

Phenotypes & Variants

Disruption phenotype

RNAi-mediated knockdown reduces expression of sod-3 (PubMed:28940692).
RNAi-mediated knockdown on a cep-1 mutant background increases germ cell apoptosis (PubMed:28940692).

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00001681571-372Zinc finger protein dpff-1

Proteomic databases

Expression

Developmental stage

Expressed throughout all embryonic and post-embryonic stages.

Gene expression databases

    • WBGene00016200Expressed in pharyngeal muscle cell (C elegans) and 4 other cell types or tissues

Interaction

Complex viewer

View interactors in UniProtKB
View CPX-1031 in Complex Portal

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for compositional bias, region, zinc finger.

Type
IDPosition(s)Description
Compositional bias108-130Polar residues
Region108-204Disordered
Compositional bias171-197Polar residues
Zinc finger212-235C2H2-type
Zinc finger256-314PHD-type 1
Zinc finger316-361PHD-type 2

Sequence similarities

Belongs to the requiem/DPF family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence & Isoforms

Align isoforms (3)
  • Sequence status
    Complete

This entry describes 3 isoforms produced by Alternative splicing.

Q09477-1

This isoform has been chosen as the canonical sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

  • Length
    372
  • Mass (Da)
    42,418
  • Last updated
    2002-08-02 v2
  • Checksum
    2A6DA04EDDC619B2
MISENGYMDLMRNCIKWNSRQMEDRKKRLRFPYYEHQTATAQRESRFTTRNVDHMYPSNDPNTVVQFATERWKKSKSQPPSDAVEMSMFLRENPSIQVAIDHLTPQVVGPTTESVSDSSNDSTTIRPSRQTQIKEEYRDDYVLDDELSPDEFGSDEDDWSSRKRRKGNLGPVQKATSSRKKVPTTRSSVSRLTPSRSIVKETKYEEPEEKTYPCDKCSAKYKSLAGLSYHQSYLHDQKSSQPLVKLLSPSIEISTSCDFCSGTAFMNKNTKLPEDLVSCHDCGRSGHPSCLNFNQNVTKIIKRSGWQCLECKSCTICGTSENDDKLLFCDDCDRGYHLYCLTPALEKAPDDEYSCRLCQVEFGDKASAPAKK

Q09477-2

  • Name
    b
  • See also
    sequence in UniParc or sequence clusters in UniRef
  • Differences from canonical

Q09477-3

Features

Showing features for compositional bias, alternative sequence.

Type
IDPosition(s)Description
Compositional bias108-130Polar residues
Alternative sequenceVSP_057651112in isoform c
Compositional bias171-197Polar residues
Alternative sequenceVSP_057652182-192in isoform b and isoform c
Alternative sequenceVSP_057653193-372in isoform b and isoform c

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
FO080703
EMBL· GenBank· DDBJ
CCD65970.1
EMBL· GenBank· DDBJ
Genomic DNA
FO080703
EMBL· GenBank· DDBJ
CCD65971.1
EMBL· GenBank· DDBJ
Genomic DNA
FO080703
EMBL· GenBank· DDBJ
CCD65978.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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