Q08119 · ESC8_YEAST

Function

function

Involved in HMR and telomere silencing via the recruitment or stabilizing of the SIR (silent information regulators) complex.

Miscellaneous

Present with 432 molecules/cell in log phase SD medium.

GO annotations

AspectTerm
Cellular Componentcytoplasm
Cellular Componentnucleus
Biological Processheterochromatin formation
Biological Processsister chromatid cohesion

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Protein ESC8
  • Alternative names
    • Establishes silent chromatin protein 8

Gene names

    • Name
      ESC8
    • Ordered locus names
      YOL017W

Organism names

Accessions

  • Primary accession
    Q08119
  • Secondary accessions
    • D6W249

Proteomes

Organism-specific databases

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00002276941-714Protein ESC8

Proteomic databases

PTM databases

Interaction

Subunit

Interacts with GAL11 and SIR2.

Protein-protein interaction databases

Miscellaneous

Structure

Family & Domains

Features

Showing features for region, compositional bias.

Type
IDPosition(s)Description
Region598-674Disordered
Compositional bias628-649Acidic residues
Compositional bias650-674Basic and acidic residues
Region694-714Disordered

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    714
  • Mass (Da)
    82,189
  • Last updated
    1996-11-01 v1
  • MD5 Checksum
    596D540E7CAF7BED03F8B13A8779C141
MTEIIDLDLVDDFIKKPMVKQQKNQSSKPRVKRRGQLTFDDFRNIKIVEEPVVLSHNSSIDESLDAATQNTKKREKYEGTCDEEMKTKEMEANMASKYSNIKTHSNDTNKVESISEHTTSNNRPLNTLNWSPNIPLRYSDFAKFMSDETVTESNWAPPLCTPLPYAGDVMKILSFIVKFKWVFSDDLLNLSFQDVEIGLELKVAGHSAKNIRICQDKMNLLFCSLLRLLFCSEKRADNQTHRNFTLKRFLSLKNPYGKLVGKLRSLIQEWGLPKEWRGNSDILSTLNFNGGGLLTMEPLDRIILLRCMIDWNCSYSALFHNEIQRLTHLKGDTGFNHQTFHASRFAMCGANNILDSCEVLCSLMSQKLENRKKRKPSDKGKLSKINSQMKFLKGVRKSLSEKVTTDRLRAAVKINEEWGEYFANEFTHTPIDDPTVDEIYKLRTSEFMIARIPRVGDFYLPPFWIGNECSSVNTSYSFNDMSTYLNYFVKFKEEGTKILPAKTAQNENKCQLKLIYRNTPACIRNLQFNDVHFAEVPHWFEVAGDSNSLSNFIEYLESLSSLTENDTDDTKKGIDNLIEFLKIFSIFINETIQRITAAPTGSTEGRHLRTSSQRRTTVHYSSDVNGDVSEESENEVDIDVSDDYDSEYLSEENTLTRKGEDRTDKSFGKRELHNGAKDCDRNCDDIEIFSEPVRQLQDNSREKRSLRRNARKGL

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias628-649Acidic residues
Compositional bias650-674Basic and acidic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
Z74759
EMBL· GenBank· DDBJ
CAA99016.1
EMBL· GenBank· DDBJ
Genomic DNA
BK006948
EMBL· GenBank· DDBJ
DAA10765.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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