Q07465 · RNI_AERHY
- ProteinRibonuclease
- StatusUniProtKB reviewed (Swiss-Prot)
- Organism
- Amino acids215 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score4/5
Function
function
One of the few RNases that cleave the phosphodiester bond between any two nucleotide. Shows a preference for adenylic acid.
Kinetics
KM | SUBSTRATE | pH | TEMPERATURE[C] | NOTES | EVIDENCE | |
---|---|---|---|---|---|---|
0.4 mM | ApA (periplasmic form) | |||||
0.08 mM | ApA (cytoplasmic form) | |||||
0.8 mM | GpA (periplasmic form) | |||||
0.2 mM | GpA (cytoplasmic form) | |||||
1 mM | CpA (periplasmic form) | |||||
0.2 mM | CpA (cytoplasmic form) | |||||
1 mM | UpA (periplasmic form) | |||||
0.3 mM | UpA (cytoplasmic form) |
Features
Showing features for active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Active site | 62 | |||||
Sequence: H | ||||||
Active site | 102 | |||||
Sequence: E | ||||||
Active site | 106 | |||||
Sequence: H |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Cellular Component | periplasmic space | |
Molecular Function | ribonuclease T2 activity | |
Molecular Function | RNA binding | |
Biological Process | RNA catabolic process |
Keywords
- Molecular function
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameRibonuclease
- EC number
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Aeromonadales > Aeromonadaceae > Aeromonas
Accessions
- Primary accessionQ07465
PTM/Processing
Features
Showing features for signal, chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Signal | 1-22 | |||||
Sequence: MKKIVVLLGMLLAPWFSSAVQA | ||||||
Chain | PRO_0000030962 | 23-215 | Ribonuclease | |||
Sequence: KGEAGEFDYYAMALSWSPEHCAIKPADRDQCSRQLGFVLHGLWPQYQRGYPSSCTRERLDPAMEQEFAGLYPSRFLYRHEWEKHGTCSGLSQHDFHQLASDLRQKREDPGRLSVSCRAAAQKPLPAQGGSGQCQRLAGPGQHHGGLRRRWRFLREVYICLNKEGTDAVTCSDEMQKRELPSCGQPDFLLRTVR |
Structure
Sequence
- Sequence statusComplete
- Sequence processingThe displayed sequence is further processed into a mature form.
- Length215
- Mass (Da)24,410
- Last updated1994-10-01 v1
- Checksum4442BCE5B0F67203