Q06738 · RD29A_ARATH

Function

function

Involved in responses to abiotic stresses (PubMed:21374086).
Regulates probably root elongation in cold conditions (PubMed:19470100).

Caution

An article reported induction by MKK1, MKK2 and MKK3 in response to drought and salt stresses; however, this paper was later retracted.

Biotechnology

The cold-inducible promoter of RD29A can be used to improve chill-resistance of crops by triggering the expression of given genes in low temperature conditions (e.g. potato low temperature sweetening).

GO annotations

all annotationsall molecular functionnucleotide bindingmolecular_functionnucleic acid bindingdna bindingchromatin bindingdna-binding transcription factor activityrna bindingcytoskeletal motor activitycatalytic activitynuclease activitysignaling receptor bindingstructural molecule activitytransporter activitybindingprotein bindingtranslation factor activity, rna bindinglipid bindingkinase activitytransferase activityhydrolase activityoxygen bindingenzyme regulator activitycarbohydrate bindingsignaling receptor activitytranslation regulator activitytranscription regulator activityother molecular functionall biological processcarbohydrate metabolic processgeneration of precursor metabolites and energynucleobase-containing compound metabolic processdna metabolic processtranslationlipid metabolic processtransportresponse to stresscell cyclecell communicationsignal transductioncell-cell signalingmulticellular organism developmentcircadian rhythmbiological_processmetabolic processcatabolic processbiosynthetic processresponse to light stimulusresponse to external stimulustropismresponse to biotic stimulusresponse to abiotic stimulusresponse to endogenous stimulusembryo developmentpost-embryonic developmentfruit ripeningabscissionpollinationflower developmentcellular processprogrammed cell deathphotosynthesiscellular component organizationcell growthprotein metabolic processcellular homeostasissecondary metabolic processreproductive processcell differentiationprotein modification processgrowthepigenetic regulation of gene expressionresponse to chemicalanatomical structure developmentregulation of molecular functionother biological processall cellular componentcellular_componentextracellular regioncell wallintracellular anatomical structurenucleusnuclear envelopenucleoplasmnucleoluscytoplasmmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuscytosolribosomecytoskeletonplasma membranechloroplastplastidthylakoidmembraneexternal encapsulating structureother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytoplasm
Cellular Componentcytosol
Cellular Componentplastid
Biological Processcircadian rhythm
Biological Processhyperosmotic salinity response
Biological Processleaf senescence
Biological Processregulation of root development
Biological Processresponse to abscisic acid
Biological Processresponse to cold
Biological Processresponse to mannitol
Biological Processresponse to osmotic stress
Biological Processresponse to reactive oxygen species
Biological Processresponse to salt
Biological Processresponse to salt stress
Biological Processresponse to symbiotic bacterium
Biological Processresponse to water deprivation
Biological Processresponse to wounding

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Low-temperature-induced 78 kDa protein
  • Alternative names
    • Desiccation-responsive protein 29A

Gene names

    • Name
      RD29A
    • Synonyms
      COR78
      , LTI140
      , LTI78
    • ORF names
      K24M7.4
    • Ordered locus names
      At5g52310

Organism names

  • Taxonomic identifier
  • Strains
    • cv. Columbia
    • cv. Landsberg erecta
    • cv. RLD
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis

Accessions

  • Primary accession
    Q06738
  • Secondary accessions
    • Q04981
    • Q39060
    • Q56Y03
    • Q93Y41

Proteomes

Organism-specific databases

Genome annotation databases

Subcellular Location

Keywords

Phenotypes & Variants

Disruption phenotype

Enhanced root growth, photosynthesis and water use efficiency (WUE) under salt stress.

Variants

We now provide the "Disease & Variants" viewer in its own tab.

The viewer provides 76 variants from UniProt as well as other sources including ClinVar and dbSNP.

Go to variant viewer

PTM/Processing

Features

Showing features for chain, modified residue.

TypeIDPosition(s)Description
ChainPRO_00000845111-710Low-temperature-induced 78 kDa protein
Modified residue626Phosphoserine

Keywords

Proteomic databases

PTM databases

Expression

Tissue specificity

Accumulates rapidly in leaves, stems, roots, flower petals, filaments, and sepals during cold-acclimation.

Induction

Levels follow a circadian cycle with higher levels during the day, in a calcium ion-dependent manner (PubMed:17227550).
Triggered by water stress, osmotic stress (e.g. salt and mannitol), diacylglycerol pyrophosphate (DGPP) and abscisic acid (ABA) (PubMed:12694590, PubMed:16463099, PubMed:16766676, PubMed:1830821, PubMed:21374086, PubMed:8148648, PubMed:8448363, PubMed:9418048).
Pretreatment with lanthanum, a calcium-channel blocker, prevents mannitol-mediated induction (PubMed:9418048).
Induced reversibly by low temperature; by both acute (2-24 hours at 4 degrees Celsius) and chronic (5-6 weeks at 10 degrees Celsius) cold treatments (PubMed:12694590, PubMed:17227550, PubMed:1830821, PubMed:19470100, PubMed:21374086, PubMed:8148648, PubMed:8290624, PubMed:8448363).
Levels are correlated with the rate of root elongation in the cold (PubMed:19470100).
Induced by the plant growth promoting rhizobacteria (PGPRs) Enterobacter sp. EJ01 (PubMed:24598995).
Triggered by WRKY8 during salt stress via direct promoter regulation in a pathway that involves PP2CG1 (PubMed:21374086, PubMed:22627139, PubMed:23451802).
Induction by salt is also ethylene-dependent, with the intervention of EIN3 that activates ESE1, the transcription regulator of the pathway (PubMed:21832142).
The salt-mediated accumulation involves reactive oxygen species (ROS), ROS-dependent induction being repressed by the NADPH oxidase inhibitor diphenylene iodonium (DPI) (PubMed:21677096).
Stimulated reversibly via histone modifications (e.g. enrichment of H3K9ac and H3K4me3) by wounding and water deprivation (PubMed:18779215, PubMed:22505693, PubMed:22983672).
Inactivated via histone modifications after rehydration (e.g. removal of H3K9ac and reduction of H3K4me3) (PubMed:22505693).
At 22 degrees Celsius, induced synergistically by osmotic stress and ABA. In cold conditions, however, impaired induction by osmotic stress but induced synergistically by cold and ABA (PubMed:9880362).

Gene expression databases

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for region, compositional bias, repeat.

TypeIDPosition(s)Description
Region1-198Disordered
Compositional bias11-30Basic and acidic residues
Compositional bias57-73Acidic residues
Compositional bias135-167Basic and acidic residues
Compositional bias168-186Polar residues
Region225-269Disordered
Repeat303-3161-1
Region303-3702 X 14 AA repeats of P-[MV]-G-F-G-[DS]-E-S-G-A-E-L-E-K
Region305-507Disordered
Compositional bias310-330Basic and acidic residues
Repeat317-3312-1
Region317-4123 X 15 AA repeats of [DN]-[FS]-P-[STV]-R-S-H-[DE]-[FL]-D-[LM]-K-[NT]-E-[ST]
Repeat336-3502-2
Repeat357-3701-2
Compositional bias366-382Basic and acidic residues
Repeat398-4122-3
Compositional bias404-422Basic and acidic residues
Compositional bias436-504Basic and acidic residues
Repeat510-5143-1
Region510-6005 X 5 AA repeats of [FV]-[ADT]-[EST]-[KM]-L
Repeat532-5363-2
Region537-577Disordered
Repeat550-5543-3
Repeat579-5833-4
Repeat596-6003-5
Compositional bias601-635Basic and acidic residues
Region601-710Disordered
Repeat648-6704-1
Region648-6962 X 23 AA repeats
Repeat674-6964-2

Sequence similarities

Belongs to the LTI78/LTI65 family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    710
  • Mass (Da)
    77,856
  • Last updated
    1995-11-01 v2
  • Checksum
    9C6C8ACAE6BDF334
MDQTEEPPLNTHQQHPEEVEHHENGATKMFRKVKARAKKFKNSLTKHGQSNEHEQDHDLVEEDDDDDELEPEVIDAPGVTGKPRETNVPASEEIIPPGTKVFPVVSSDYTKPTESVPVQEASYGHDAPAHSVRTTFTSDKEEKRDVPIHHPLSELSDREESRETHHESLNTPVSLLSGTEDVTSTFAPSGDDEYLDGQRKVNVETPITLEEESAVSDYLSGVSNYQSKVTDPTKEETGGVPEIAESFGNMEVTDESPDQKPGQFERDLSTRSKEFKEFDQDFDSVLGKDSPAKFPGESGVVFPVGFGDESGAELEKDFPTRSHDFDMKTETGMDTNSPSRSHEFDLKTESGNDKNSPMGFGSESGAELEKEFDQKNDSGRNEYSPESDGGLGAPLGGNFPVRSHELDLKNESDIDKDVPTGFDGEPDFLAKGRPGYGEASEEDKFPARSDDVEVETELGRDPKTETLDQFSPELSHPKERDEFKESRDDFEETRDEKTEEPKQSTYTEKFASMLGYSGEIPVGDQTQVAGTVDEKLTPVNEKDQETESAVTTKLPISGGGSGVEEQRGEDKSVSGRDYVAEKLTTEEEDKAFSDMVAEKLQIGGEEEKKETTTKEVEKISTEKAASEEGEAVEEEVKGGGGMVGRIKGWFGGGATDEVKPESPHSVEEAPKSSGWFGGGATEEVKPKSPHSVEESPQSLGSTVVPVQKEL

Features

Showing features for compositional bias, sequence conflict.

TypeIDPosition(s)Description
Compositional bias11-30Basic and acidic residues
Compositional bias57-73Acidic residues
Compositional bias135-167Basic and acidic residues
Compositional bias168-186Polar residues
Sequence conflict216in Ref. 2; BAA02376
Compositional bias310-330Basic and acidic residues
Compositional bias366-382Basic and acidic residues
Compositional bias404-422Basic and acidic residues
Compositional bias436-504Basic and acidic residues
Sequence conflict491in Ref. 2; BAA02376
Sequence conflict514in Ref. 8; CAA40826
Sequence conflict535in Ref. 3; AAA32776
Compositional bias601-635Basic and acidic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
X67671
EMBL· GenBank· DDBJ
CAA47903.1
EMBL· GenBank· DDBJ
Genomic DNA
D13044
EMBL· GenBank· DDBJ
BAA02376.1
EMBL· GenBank· DDBJ
Genomic DNA
L22567
EMBL· GenBank· DDBJ
AAA32775.1
EMBL· GenBank· DDBJ
mRNA
L22568
EMBL· GenBank· DDBJ
AAA32776.1
EMBL· GenBank· DDBJ
Genomic DNA
AB019226
EMBL· GenBank· DDBJ
BAB10528.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002688
EMBL· GenBank· DDBJ
AED96199.1
EMBL· GenBank· DDBJ
Genomic DNA
AY054465
EMBL· GenBank· DDBJ
AAK96657.1
EMBL· GenBank· DDBJ
mRNA
AK221520
EMBL· GenBank· DDBJ
BAD94805.1
EMBL· GenBank· DDBJ
mRNA
X57600
EMBL· GenBank· DDBJ
CAA40826.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

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