Q06601 · APD14_APIME
- ProteinApidaecins type 14
- GeneAPID14
- StatusUniProtKB reviewed (Swiss-Prot)
- Organism
- Amino acids168 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score3/5
Function
function
Apidaecins have bactericidal activity; predominantly against Gram-negative bacteria (PubMed:2676519, PubMed:7929322).
They seem to interfere with cell propagation (PubMed:2676519).
They seem to interfere with cell propagation (PubMed:2676519).
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | extracellular region | |
Biological Process | defense response to bacterium | |
Biological Process | innate immune response |
Keywords
- Molecular function
- Biological process
Names & Taxonomy
Protein names
- Recommended nameApidaecins type 14
- Cleaved into 3 chains
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Hymenoptera > Apocrita > Aculeata > Apoidea > Anthophila > Apidae > Apis
Accessions
- Primary accessionQ06601
- Secondary accessions
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for signal, propeptide, peptide.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Signal | 1-19 | ||||
Propeptide | PRO_0000004910 | 20-42 | |||
Peptide | PRO_0000004911 | 43-60 | Apidaecin-2 | ||
Propeptide | PRO_0000004912 | 63-70 | |||
Peptide | PRO_0000004913 | 71-88 | Apidaecin-2 | ||
Propeptide | PRO_0000004914 | 91-98 | |||
Peptide | PRO_0000004915 | 99-116 | Apidaecin-1B | ||
Propeptide | PRO_0000004916 | 119-124 | |||
Peptide | PRO_0000004917 | 125-142 | Apidaecin-1B | ||
Propeptide | PRO_0000004918 | 145-150 | |||
Peptide | PRO_0000004919 | 151-168 | Apidaecin-1A | ||
Keywords
- PTM
Proteomic databases
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for region.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Region | 20-168 | Disordered | |||
Sequence similarities
Belongs to the apidaecin family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Sequence processingThe displayed sequence is further processed into a mature form.
- Length168
- Mass (Da)19,380
- Last updated1994-06-01 v1
- Checksum594B931254C04A37
Mass Spectrometry
Apidaecin-1B
Molecular mass is 2,110 Da. Determined by MALDI. Apidaecin-1B.Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
X72575 EMBL· GenBank· DDBJ | CAA51167.1 EMBL· GenBank· DDBJ | mRNA |