BRD4 inhibition impairs DNA mismatch repair, induces mismatch repair mutation signatures and creates therapeutic vulnerability to immune checkpoint blockade in MMR-proficient tumors.
- AnnotationBRD4 inhibition impairs DNA mismatch repair induces mismatch repair mutation signatures and creates therapeutic vulnerability to immune checkpoint blockade in MMR-proficient tumors.
- CategoriesFunction, Expression
- SourceGeneRif: 23476