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Q04F24 · BGAL_OENOB

Function

Catalytic activity

  • Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.
    EC:3.2.1.23 (UniProtKB | ENZYME | Rhea)

Cofactor

Protein has several cofactor binding sites:
Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Note: Binds 2 magnesium ions per monomer.
Na+ (UniProtKB | Rhea| CHEBI:29101 )

Note: Binds 1 sodium ion per monomer.

Features

Showing features for binding site, site, active site.

110311002003004005006007008009001,000
Type
IDPosition(s)Description
Binding site98substrate
Binding site197Na+ (UniProtKB | ChEBI)
Binding site197substrate
Site353Transition state stabilizer
Site387Transition state stabilizer
Binding site412Mg2+ 1 (UniProtKB | ChEBI)
Binding site414Mg2+ 1 (UniProtKB | ChEBI)
Active site457Proton donor
Binding site457Mg2+ 1 (UniProtKB | ChEBI)
Binding site457substrate
Active site533Nucleophile
Binding site533-536substrate
Binding site593Mg2+ 2 (UniProtKB | ChEBI)
Binding site597Na+ (UniProtKB | ChEBI)
Binding site600Na+ (UniProtKB | ChEBI)
Binding site600substrate
Binding site1005substrate

GO annotations

AspectTerm
Cellular Componentbeta-galactosidase complex
Molecular Functionbeta-galactosidase activity
Molecular Functioncarbohydrate binding
Molecular Functionmagnesium ion binding
Biological Processlactose catabolic process

Keywords

Enzyme and pathway databases

Protein family/group databases

    • GH2Glycoside Hydrolase Family 2

Names & Taxonomy

Protein names

  • Recommended name
    Beta-galactosidase
  • EC number
  • Short names
    Beta-gal
  • Alternative names
    • Lactase

Gene names

    • Name
      lacZ
    • Ordered locus names
      OEOE_1044

Organism names

Accessions

  • Primary accession
    Q04F24

Proteomes

Subcellular Location

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00003670041-1031Beta-galactosidase

Interaction

Subunit

Homotetramer.

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the glycosyl hydrolase 2 family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,031
  • Mass (Da)
    118,758
  • Last updated
    2006-11-14 v1
  • MD5 Checksum
    35CCF21C7CA16A75BFB6811C1B8D1083
MTNKISFRDIINRKDWENPVITNWHRLPIHTEMNYSKSLNEDKQKTIQSLNGNWCFSYFSKVTDVPENWADRDLTKSNIMPVPSNWQLHGYDQPIYSNVAYPFPANPPYLPEENPTACYSRIFQLNDDWLQSGQNHVIFNGVGSAFHLWLNGQWIGYSEDSRLPAEFDLTKYLKSGKNRISVMVLRWSKGSYFEDQDMWRMSGIFRDVEVKHLPATYLQDYQLQTDLDDDLDQAKITIKAQVAGKNFSQNKLRTRLYFANEKVADQSSRLSTRAVDERGPLDNQFIAELNLKDPYLWSAELPYLYQLVIELLTDDGDILQVEKVNIGVRKVEIKNGLLKLNGKPLLIRGTNKHEFDSKKGYAVDEETMIQDIKAMKRNNFNAVRCSHYPNNRRWYELCDQYGLYVVDEANIETHGMVPMNRLTNDPVYLPLMSDRVTRMVTRDRNHPSIIIWSLGNESGYGRNHAALYNWIKQSDLSRPVQYEGGGANTAVTDIIVPMYARVEQDQIESVNSKWSLKKWIGLPGETRPLILCEYAHDMGNSLGGFGKYWQAFHKYPRLQGGFIWDWVDQGLLKKDVNGNDFYAYGGDFKDQPNDRQFCLDGLLFPDRTPKPAMHEVKYWQQYYLFNLQRNPLGQAESFTVTNDYSFKKSSNERLHYQIKSENEIVIDKYIDLVLNPGESLLIKLPKGRSSTSSLLDIDISLIKGNSWAPSGFKIASEQYVLAKKFGPTNAVTAATNKISLIENKDTNTFEIKLDDQKWQFAKNSGLLVSWSKSGNENLLDALRDQFTRAPLDNDIGVSKVDHIDPNAWYERWKSAGMYNLKTNLVSIDAEQLERAVLIRTEHSYSNHFQILFKSSKIYRIDANGTMTVTVDVSLAQGIPFPARIGLTCHLADQITDVSYTGLGPFENYPDRQSAAQYGHWQMELDDLYTPYIFPSENGSRGQVSQLEFGKQKISAYHEQNFSFNLSRFSKQQLARISHRNLLQAENGVWLSIDGYRMGVGGDDSWSPSVAPEYLLSNNYYHYAFQWCRKDI

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP000411
EMBL· GenBank· DDBJ
ABJ56948.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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