Q04809 · DPAA_BACSU

Function

function

Together with DpaB, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA), which constitutes up to 10% of the dry weight of the spore.

Catalytic activity

Features

Showing features for binding site.

129720406080100120140160180200220240260280
TypeIDPosition(s)Description
Binding site164-165NADP+ (UniProtKB | ChEBI)
Binding site185NADP+ (UniProtKB | ChEBI)
Binding site203NADP+ (UniProtKB | ChEBI)
Binding site242-244NADP+ (UniProtKB | ChEBI)
Binding site264-267NADP+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Functionoxidoreductase activity
Biological Processsporulation resulting in formation of a cellular spore

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Dipicolinate synthase subunit A
  • EC number
  • Short names
    DPA synthase subunit A
  • Alternative names
    • Spore dipicolinate synthase subunit A
    • Stage V sporulation protein FA

Gene names

    • Name
      dpaA
    • Synonyms
      spoVFA
    • ORF names
      orfY
    • Ordered locus names
      BSU16730

Organism names

Accessions

  • Primary accession
    Q04809

Proteomes

Phenotypes & Variants

Disruption phenotype

Disruption of this gene has no effect on vegetative growth but causes a sporulation defect, characterized by heat-sensitive spores devoid of DPA, which can be cured by supplementation with dipicolinate.

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00000720831-297Dipicolinate synthase subunit A

Proteomic databases

Expression

Induction

Is not expressed during vegetative growth; is expressed at stage 5 of sporulation specifically in the mother cell compartment, under the control of the sigma-K factor. Is repressed by GerE.

Interaction

Subunit

Dipicolinate synthase likely consists of DpaA and DpaB, since both proteins are required for DPA synthesis.

Protein-protein interaction databases

Family & Domains

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    297
  • Mass (Da)
    31,948
  • Last updated
    1993-10-01 v1
  • Checksum
    634B14D514B041B9
MLTGLKIAVIGGDARQLEIIRKLTEQQADIYLVGFDQLDHGFTGAVKCNIDEIPFQQIDSIILPVSATTGEGVVSTVFSNEEVVLKQDHLDRTPAHCVIFSGISNAYLENIAAQAKRKLVKLFERDDIAIYNSIPTVEGTIMLAIQHTDYTIHGSQVAVLGLGRTGMTIARTFAALGANVKVGARSSAHLARITEMGLVPFHTDELKEHVKDIDICINTIPSMILNQTVLSSMTPKTLILDLASRPGGTDFKYAEKQGIKALLAPGLPGIVAPKTAGQILANVLSKLLAEIQAEEGK

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
L08471
EMBL· GenBank· DDBJ
AAA22381.1
EMBL· GenBank· DDBJ
Genomic DNA
Z22554
EMBL· GenBank· DDBJ
CAA80274.1
EMBL· GenBank· DDBJ
Genomic DNA
AL009126
EMBL· GenBank· DDBJ
CAB13546.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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