Q04688 · ELG_DROME
- ProteinDNA-binding protein Ets97D
- GeneEts97D
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids464 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score5/5
Function
function
May have a role in germline development.
Features
Showing features for dna binding.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
DNA binding | 346-426 | ETS | ||||
Sequence: VQLWQFLLEILTDCEHTDVIEWVGTEGEFKLTDPDRVARLWGEKKNKPAMNYEKLSRALRYYYDGDMISKVSGKRFAYKFD |
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | nucleus | |
Molecular Function | DNA-binding transcription factor activity, RNA polymerase II-specific | |
Molecular Function | sequence-specific DNA binding | |
Biological Process | cellular response to starvation | |
Biological Process | positive regulation of oxidative phosphorylation | |
Biological Process | positive regulation of transcription by RNA polymerase II | |
Biological Process | regulation of glutamine family amino acid metabolic process | |
Biological Process | regulation of mitochondrion organization | |
Biological Process | regulation of transcription by RNA polymerase II |
Keywords
- Molecular function
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameDNA-binding protein Ets97D
- Short namesD-elg
Gene names
Organism names
- Strains
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Diptera > Brachycera > Muscomorpha > Ephydroidea > Drosophilidae > Drosophila > Sophophora
Accessions
- Primary accessionQ04688
- Secondary accessions
Proteomes
Organism-specific databases
Subcellular Location
PTM/Processing
Features
Showing features for chain, modified residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000204094 | 1-464 | DNA-binding protein Ets97D | |||
Sequence: MNSSNDLSDELIRRLSVGGALEEVIASEMFEDSIDVETEAEPDDIIIVHMDIREPLSMLKSLVEQKIGVCLNYYTFWLQDAQELESHKNLVDQCVKGEGLVQINVQIQTIRKRINIADVLKPTEAALAALAEEVVGQLSPPETASQKSSSSESPIKTPLKRMHKEDSEEESVEGKDVKPVLNWVLDSKFKREQIRLKIPEAANEWTHAHVTYWLEWAVKQFELVGINMSDWQMNGQELCAMTHEEFNQKLPRDPGNIFWTHLQLLKECNFVSVVHKRAEEQRKPKQPRIMSANSISTNSGGSLSLEQRIMRKSYQSVKSSDSVESTTSSMNPSNYTTIGSGNNGQVQLWQFLLEILTDCEHTDVIEWVGTEGEFKLTDPDRVARLWGEKKNKPAMNYEKLSRALRYYYDGDMISKVSGKRFAYKFDCDLKLLIGYDANELSTLVSEGKTAPERVAATETITEDT | ||||||
Modified residue | 153 | Phosphoserine | ||||
Sequence: S | ||||||
Modified residue | 157 | Phosphothreonine | ||||
Sequence: T | ||||||
Modified residue | 167 | Phosphoserine | ||||
Sequence: S | ||||||
Modified residue | 171 | Phosphoserine | ||||
Sequence: S |
Keywords
- PTM
Proteomic databases
PTM databases
Expression
Tissue specificity
Uniform distribution throughout embryonic development, with slightly higher expression in pole cells.
Developmental stage
Expressed throughout development with lower levels during larval development.
Gene expression databases
Structure
Family & Domains
Features
Showing features for region, compositional bias, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 138-173 | Disordered | ||||
Sequence: LSPPETASQKSSSSESPIKTPLKRMHKEDSEEESVE | ||||||
Compositional bias | 139-156 | Polar residues | ||||
Sequence: SPPETASQKSSSSESPIK | ||||||
Compositional bias | 157-173 | Basic and acidic residues | ||||
Sequence: TPLKRMHKEDSEEESVE | ||||||
Domain | 184-269 | PNT | ||||
Sequence: VLDSKFKREQIRLKIPEAANEWTHAHVTYWLEWAVKQFELVGINMSDWQMNGQELCAMTHEEFNQKLPRDPGNIFWTHLQLLKECN | ||||||
Region | 281-300 | Disordered | ||||
Sequence: QRKPKQPRIMSANSISTNSG |
Sequence similarities
Belongs to the ETS family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length464
- Mass (Da)52,644
- Last updated2007-10-23 v2
- Checksum258A038E8DF427A2
Computationally mapped potential isoform sequences
There is 1 potential isoform mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A0B4KHY6 | A0A0B4KHY6_DROME | Ets97D | 484 |
Sequence caution
Features
Showing features for compositional bias, sequence conflict.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 139-156 | Polar residues | ||||
Sequence: SPPETASQKSSSSESPIK | ||||||
Compositional bias | 157-173 | Basic and acidic residues | ||||
Sequence: TPLKRMHKEDSEEESVE | ||||||
Sequence conflict | 454 | in Ref. 1; CAA48327 and 5; CAA41390 | ||||
Sequence: V → L |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
X68259 EMBL· GenBank· DDBJ | CAA48327.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AE014297 EMBL· GenBank· DDBJ | AAF56638.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AY070960 EMBL· GenBank· DDBJ | AAL48582.1 EMBL· GenBank· DDBJ | mRNA | Frameshift | |
BT025224 EMBL· GenBank· DDBJ | ABF17915.1 EMBL· GenBank· DDBJ | mRNA | ||
M88471 EMBL· GenBank· DDBJ | AAC34199.1 EMBL· GenBank· DDBJ | mRNA | ||
X58481 EMBL· GenBank· DDBJ | CAA41390.1 EMBL· GenBank· DDBJ | mRNA | Sequence problems. |