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Q041L3 · RTPR_LACGA

Function

Catalytic activity

Cofactor

adenosylcob(III)alamin (UniProtKB | Rhea| CHEBI:18408 )

Activity regulation

Allosterically regulated by ATP and dNTP.

Features

Showing features for active site.

TypeIDPosition(s)Description
Active site413
Active site415

GO annotations

AspectTerm
Molecular Functioncobalamin binding
Molecular Functionnucleotide binding
Molecular Functionribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
Molecular Functionribonucleoside-triphosphate reductase (thioredoxin) activity
Biological ProcessDNA replication

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Adenosylcobalamin-dependent ribonucleoside-triphosphate reductase
  • EC number
  • Short names
    RTPR

Gene names

    • Name
      rtpR
    • Ordered locus names
      LGAS_1503

Organism names

Accessions

  • Primary accession
    Q041L3

Proteomes

PTM/Processing

Features

Showing features for chain, disulfide bond.

Type
IDPosition(s)Description
ChainPRO_00003265411-744Adenosylcobalamin-dependent ribonucleoside-triphosphate reductase
Disulfide bond120↔424Redox-active

Keywords

Interaction

Subunit

Monomer.

Structure

Family & Domains

Features

Showing features for region.

TypeIDPosition(s)Description
Region148-159Effector region-1
Region169-318Effector region-2
Region570-631Adenosylcobalamin-binding-1
Region690-729Adenosylcobalamin-binding-2

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    744
  • Mass (Da)
    83,638
  • Last updated
    2008-04-08 v2
  • MD5 Checksum
    C9688081E6146BE896F30972D79506BB
MSDLRITLDPDFIAQTKKEVTPHWGELGWVTYKRTYARWLDDKNRSENWDETVKRVIEGNINLDPRLKNNPSKKTIHELTAEAKQLFRLVYGLAATPSGRNLWISGTDYQKRNGDSLNNCWFISIRPQKYGNSHIVPAYLTQDQVAPSMPFSFLFDQLMKGGGVGFSVVDENINQIPKLDQKVDLTIVIDKQSKSYDASLKLGATDLDEWKKTNQEKEDYIYYKLPDTREGWVLANARLIDMHFNSTNPENKKKLVLDISDIRPYGAKIHGFGGTASGPMPLIEMLFDINQILNERAGQKLTAVDATDICNLIGKTVVAGNVRRSAELALGSSNNQDFITMKQDKKKLYHHRWASNNSVAINSEFDNYQPIADSILHNGEPGVVNLELSRNYGRIKDGYQAGIDGEVEGTNPCGEISLANGEPCNLFEVFPFIAQKQGWDLKEAFKLAARYTKRVTFSPYDWEVSRKIINKNRRIGVSMSGIQDWILSTFGHRVVTGFKTATDSETGKEIKDPVYDPEIIKTVDGLYQAVVDADKDYSQELNCNTSIKHTTVKPSGTVAKLAGVSEGMHFHYSGYLIQRIRFQETDPLLPALKDCGYRTEPDIYTPHTICVEFPIKAANADSDNFASAGTVSIAEQFATQAFLQTYWSDNAVSCTITFQNDESDQIAPLLHQYRYAIKSTSLLPYYGGSLKQAPKEPISKEKYEKADNHITGNVEIVFEQTNEDQKGLELVDQSDCDNGACPIK

Sequence caution

The sequence ABJ60859.1 differs from that shown. Reason: Erroneous initiation

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP000413
EMBL· GenBank· DDBJ
ABJ60859.1
EMBL· GenBank· DDBJ
Genomic DNA Different initiation

Genome annotation databases

Similar Proteins

Disclaimer

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