Q03TT0 · GUAC_LEVBA
- ProteinGMP reductase
- GeneguaC
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids328 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
Catalytic activity
- IMP + NH4+ + NADP+ = GMP + NADPH + 2 H+
Features
Showing features for active site, binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 177 | Thioimidate intermediate | |||
Binding site | 206-229 | NADP+ (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Cellular Component | GMP reductase complex | |
Molecular Function | GMP reductase activity | |
Biological Process | purine nucleotide metabolic process |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameGMP reductase
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Bacillota > Bacilli > Lactobacillales > Lactobacillaceae > Levilactobacillus
Accessions
- Primary accessionQ03TT0
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000292050 | 1-328 | GMP reductase | ||
Interaction
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length328
- Mass (Da)36,006
- Last updated2006-11-14 v1
- ChecksumDD7A0C66BF41F14B
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP000416 EMBL· GenBank· DDBJ | ABJ63392.1 EMBL· GenBank· DDBJ | Genomic DNA |