Q03123 · T2FB_XENLA

Function

function

TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componenttranscription factor TFIIF complex
Molecular FunctionDNA binding
Biological Processtranscription by RNA polymerase II
Biological Processtranscription initiation at RNA polymerase II promoter

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    General transcription factor IIF subunit 2
  • Alternative names
    • Transcription initiation factor IIF subunit beta (TFIIF-beta)
    • Transcription initiation factor RAP30

Gene names

    • Name
      gtf2f2
    • Synonyms
      rap30

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Amphibia > Batrachia > Anura > Pipoidea > Pipidae > Xenopodinae > Xenopus > Xenopus

Accessions

  • Primary accession
    Q03123
  • Secondary accessions
    • Q6GN43

Proteomes

Organism-specific databases

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00002112381-264General transcription factor IIF subunit 2

Expression

Gene expression databases

    • 398333Expressed in gastrula and 19 other cell types or tissues

Interaction

Subunit

Heterodimer of an alpha and a beta subunit.

Structure

Family & Domains

Sequence similarities

Belongs to the TFIIF beta subunit family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    264
  • Mass (Da)
    30,140
  • Last updated
    1994-02-01 v1
  • Checksum
    A26320BA82CC4DD1
MSAEKGELDLNGAKQNTGMWLVKLPKYLAQQWAKATGRGEVGKLRIVKNQGKTEVSFTLNEELASIQDIGGKPASSLVSTPREHPFLLQSVGGQTLTVLTESLSGQSEDKSENRVIDKLALEGIVVHRAECRPAASDNYMQMKRKQIEESSKPKRQSQQLEKAVTSNYKPVSNHQYNIEYEKKKKDDGKRARVDKHQVLDMLFSAFEKHQYYNIKDLVDITKQPVTYLKEILRDIGIYNMKGTHKNTWELKPEYRHYQGEDKSD

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
Z15132
EMBL· GenBank· DDBJ
CAA78835.1
EMBL· GenBank· DDBJ
mRNA
BC073677
EMBL· GenBank· DDBJ
AAH73677.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

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