Q02892 · NOG1_YEAST
- ProteinNucleolar GTP-binding protein 1
- GeneNOG1
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids647 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score5/5
Function
function
Involved in the biogenesis of the 60S ribosomal subunit.
Miscellaneous
Present with 28000 molecules/cell in log phase SD medium.
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Cellular Component | nucleolus | |
Cellular Component | preribosome, large subunit precursor | |
Molecular Function | GTP binding | |
Molecular Function | GTPase activity | |
Molecular Function | RNA binding | |
Biological Process | assembly of large subunit precursor of preribosome | |
Biological Process | ribosomal large subunit biogenesis | |
Biological Process | ribosomal subunit export from nucleus | |
Biological Process | rRNA processing |
Keywords
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameNucleolar GTP-binding protein 1
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Ascomycota > Saccharomycotina > Saccharomycetes > Saccharomycetales > Saccharomycetaceae > Saccharomyces
Accessions
- Primary accessionQ02892
- Secondary accessions
Proteomes
Organism-specific databases
Subcellular Location
PTM/Processing
Features
Showing features for chain, modified residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000195035 | 1-647 | Nucleolar GTP-binding protein 1 | |||
Sequence: MQLSWKDIPTVAPANDLLDIVLNRTQRKTPTVIRPGFKITRIRAFYMRKVKYTGEGFVEKFEDILKGFPNINDVHPFHRDLMDTLYEKNHYKISLAAISRAKSLVEQVARDYVRLLKFGQSLFQCKQLKRAALGRMATIVKKLRDPLAYLEQVRQHIGRLPSIDPNTRTLLICGYPNVGKSSFLRCITKSDVDVQPYAFTTKSLYVGHFDYKYLRFQAIDTPGILDRPTEEMNNIEMQSIYAIAHLRSCVLYFMDLSEQCGFTIEAQVKLFHSIKPLFANKSVMVVINKTDIIRPEDLDEERAQLLESVKEVPGVEIMTSSCQLEENVMEVRNKACEKLLASRIENKLKSQSRINNVLNKIHVAQPQARDDVKRTPFIPESVKNLKKYDPEDPNRRKLARDIEAENGGAGVFNVNLKDKYLLEDDEWKNDIMPEILDGKNVYDFLDPEIAAKLQALEEEEEKLENEGFYNSDDEEEIYDGFEASEVDDIKEKAAWIRNRQKTMIAEARNRKSLKNKAIMPRSKLTKSFGKMEEHMSTLGHDMSALQDKQNRAARKNRYVERGSDVVFGDQDALTASTENGVKLRQTDRLLDGVADGSMRSKADRMAKMERRERNRHAKQGESDRHNAVSLSKHLFSGKRGVGKTDFR | ||||||
Modified residue | 563 | Phosphoserine | ||||
Sequence: S |
Keywords
- PTM
Proteomic databases
PTM databases
Interaction
Subunit
Associated with nucleolar and cytoplasmic pre-60S particles. Directly interacts with RLP24.
Binary interactions
Type | Entry 1 | Entry 2 | Number of experiments | Intact | |
---|---|---|---|---|---|
BINARY | Q02892 | DBP10 Q12389 | 3 | EBI-12105, EBI-5644 | |
BINARY | Q02892 | ERB1 Q04660 | 5 | EBI-12105, EBI-28098 | |
BINARY | Q02892 | HAS1 Q03532 | 3 | EBI-12105, EBI-8170 | |
BINARY | Q02892 | LOC1 P43586 | 5 | EBI-12105, EBI-22906 | |
BINARY | Q02892 | MAK21 Q12176 | 3 | EBI-12105, EBI-10944 | |
BINARY | Q02892 | NOP2 P40991 | 3 | EBI-12105, EBI-12110 | |
BINARY | Q02892 | NOP4 P37838 | 4 | EBI-12105, EBI-12122 | |
BINARY | Q02892 | NOP7 P53261 | 5 | EBI-12105, EBI-13145 | |
BINARY | Q02892 | NSA1 P53136 | 5 | EBI-12105, EBI-23920 | |
BINARY | Q02892 | NSA2 P40078 | 5 | EBI-12105, EBI-22681 | |
BINARY | Q02892 | RLP7 P40693 | 4 | EBI-12105, EBI-15415 | |
BINARY | Q02892 | RPF2 P36160 | 7 | EBI-12105, EBI-15881 | |
BINARY | Q02892 | RPL20B P0C2I0 | 2 | EBI-12105, EBI-15298 | |
BINARY | Q02892 | RPL2B P05736 | 2 | EBI-12105, EBI-15328 | |
BINARY | Q02892 | RPL5 P26321 | 2 | EBI-12105, EBI-15398 |
Protein-protein interaction databases
Miscellaneous
Structure
Family & Domains
Features
Showing features for domain, region, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 168-340 | OBG-type G | ||||
Sequence: RTLLICGYPNVGKSSFLRCITKSDVDVQPYAFTTKSLYVGHFDYKYLRFQAIDTPGILDRPTEEMNNIEMQSIYAIAHLRSCVLYFMDLSEQCGFTIEAQVKLFHSIKPLFANKSVMVVINKTDIIRPEDLDEERAQLLESVKEVPGVEIMTSSCQLEENVMEVRNKACEKLL | ||||||
Region | 594-647 | Disordered | ||||
Sequence: ADGSMRSKADRMAKMERRERNRHAKQGESDRHNAVSLSKHLFSGKRGVGKTDFR | ||||||
Compositional bias | 597-628 | Basic and acidic residues | ||||
Sequence: SMRSKADRMAKMERRERNRHAKQGESDRHNAV |
Sequence similarities
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length647
- Mass (Da)74,410
- Last updated1996-11-01 v1
- Checksum640324779AE4D716
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 597-628 | Basic and acidic residues | ||||
Sequence: SMRSKADRMAKMERRERNRHAKQGESDRHNAV |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
U43281 EMBL· GenBank· DDBJ | AAB68206.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
BK006949 EMBL· GenBank· DDBJ | DAA11340.1 EMBL· GenBank· DDBJ | Genomic DNA |