Q02335 · TOM70_CAEEL

  • Protein
    Mitochondrial import receptor subunit tomm-70
  • Gene
    tomm-70
  • Status
    UniProtKB reviewed (Swiss-Prot)
  • Amino acids
  • Protein existence
    Evidence at transcript level
  • Annotation score
    4/5

Function

function

Receptor that accelerates the import of all mitochondrial precursor proteins.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentmitochondrial outer membrane
Cellular Componentmitochondrion
Molecular Functionmitochondrion targeting sequence binding
Biological Processactivation of innate immune response
Biological Processcellular response to virus
Biological Processpositive regulation of defense response to virus by host
Biological Processpositive regulation of interferon-beta production
Biological Processprotein import into mitochondrial matrix
Biological Processprotein insertion into mitochondrial inner membrane
Biological Processregulation of apoptotic process

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Mitochondrial import receptor subunit tomm-70
  • Alternative names
    • Translocase of outer mitochondrial membrane 70

Gene names

    • Name
      tomm-70
    • ORF names
      ZK370.8

Organism names

  • Taxonomic identifier
  • Strain
    • Bristol N2
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Nematoda > Chromadorea > Rhabditida > Rhabditina > Rhabditomorpha > Rhabditoidea > Rhabditidae > Peloderinae > Caenorhabditis

Accessions

  • Primary accession
    Q02335

Proteomes

Organism-specific databases

Subcellular Location

Features

Showing features for topological domain, transmembrane.

TypeIDPosition(s)Description
Topological domain1-12Mitochondrial intermembrane
Transmembrane13-32Helical
Topological domain33-569Cytoplasmic

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00001064241-569Mitochondrial import receptor subunit tomm-70

Proteomic databases

Expression

Tissue specificity

Expressed in body wall muscle cells, the pharynx and structures in the tail.

Gene expression databases

Interaction

Subunit

Forms part of the preprotein translocase complex of the outer mitochondrial membrane (TOM complex).

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for repeat.

TypeIDPosition(s)Description
Repeat44-77TPR 1
Repeat119-152TPR 2
Repeat221-254TPR 3
Repeat510-544TPR 4

Sequence similarities

Belongs to the Tom70 family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    569
  • Mass (Da)
    64,867
  • Last updated
    2005-05-10 v3
  • Checksum
    E077B97655DEE902
MVETTGISDQTKKVLIGVAAAATVAGVGYLVYKSFGGSDLERDLEEIKALGNLKFKEKQYDSALEAFTKGVEKAGPNSSDQIVAMLYQNRAACREKVGHSPFDILNDCMAALKVDKKYTKAYLRAAKALNDVGKKQDALAYLLAAFTLDSSLNKTNFEFFGKLLAIEPMSDCHIGKPLKIEDVKPQPVALFRIQQWCDTWDILDLFKTDLTRFEPEVLSEDQKQYQLALEKFKKGKYEELIDLLTEENSYPPAMILRGKMLSYSTDPNEATRYIDKVGAKINELIGSEEDEERKKLMRDAFDILKIELMYTMADLDKFLESVPKDDKERLFKLYSFASIFVVIRLNHFYSLKIWFQYNGCVLDTAVTNHEQQMMADTNNANRLLTEAEKNGTLTPHLSMIVTFLKLCTSEDYADVHRRIREMEELAESRSTHFNLVLMSKVYMMTNNEESSKKLLEEAARITTRYLVPSRHLQTADLHVHKPEAERLRLTTESANAAIAVDPFNFSAHVLHLLGTNGPEPMIKKENYERAMESIRNAALFAPPRELLMLKRMIPLMNAKKRAAEMLDMY

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
BX284603
EMBL· GenBank· DDBJ
CCD61727.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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