Q01846 · MDM1_YEAST
- ProteinStructural protein MDM1
- GeneMDM1
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids1127 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score4/5
Function
function
Essential for mitotic growth. Mediates organelle inheritance.
Miscellaneous
Present with 784 molecules/cell in log phase SD medium.
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | cell periphery | |
Cellular Component | cytoplasm | |
Cellular Component | fungal-type vacuole | |
Cellular Component | intracellular membrane-bounded organelle | |
Cellular Component | nucleus-vacuole junction | |
Molecular Function | phosphatidylinositol binding | |
Molecular Function | phosphatidylinositol-3-phosphate binding | |
Biological Process | mitochondrion inheritance | |
Biological Process | piecemeal microautophagy of the nucleus | |
Biological Process | vacuole-ER tethering |
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameStructural protein MDM1
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Ascomycota > Saccharomycotina > Saccharomycetes > Saccharomycetales > Saccharomycetaceae > Saccharomyces
Accessions
- Primary accessionQ01846
- Secondary accessions
Proteomes
Organism-specific databases
Subcellular Location
PTM/Processing
Features
Showing features for chain, modified residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000096330 | 1-1127 | Structural protein MDM1 | |||
Sequence: MPKFPQFRLILVLFYLISMIQWSVITFSLGFFLNVCIFAYFVFFKSLPDLPKPQPRFVDIVPESSNTVDVDKELKSVEGLIQDGNAQIGKELESIVNLIIKDFVQPWFTKIDKNSDAEFLKVIKWRLLQTLLVVKDKLMKNDSASLIVLKLLPIFNKHFSTFCDAREAVLSDLTLERHKSANIDLQIAVEFNKNYKIHKSLSLKPNALQKEIEKSIRKTVIGLLPHLFDNDELDSLLVFTLMTEVLTTCIISPLIFKFTDPDSWNLRIVSLSQNYFEEKHKVHKIRRMLSKELQDHRKVMNDVANKDVGEPSSEKLELNAEYTGKQFEHYLNQLDSLLDLSDIKYVAYSLALKIYQLKENEHLTKENLKYKKRLLLSLNLIESKLSFPGSEIDTASKKLAREANYPDLNMDNGIVLKEMASFLTSITLKDIVDDSEFLPFFESFLGSVPETQGSTFLEYSQTIESFKNPLEDATSEDIISGYSGISTMQLQEISSKFFHNNNLQNMKLLDEGLVKNIILFRNSFQINNDEDTFILARKSVLLLQTEAIKYLDDRFLPLFKKTPSFLKMLSTSHIISTDIYAHFLSRIGGVNNPEQNKIIKDNVKTDFMNPVRIFANPGITDALDNIVNGSGSKPHKSRISSNPRYSQLFGSENDNIFKDKLFDDENDNTSEISVVEDQLDHPRNMEKVSVSSGNSGLNPSQFYGSNNFRDNIASLTISIDQIEKELELLRHLILKADLTNNQMQLKILKKSQRTLLKELEMKELLKQQYMVQENGNSLFRKTKIYIRSYFSENSSNGLKEITYYIINIHHFNNGQVSSWDMARRYNEFFELNTYLKKNFRDLMRQLQDLFPSKVKMSLKYHVTKTLLYEERKQKLEKYLRELLSISEICEDNIFRRFLTDPTPFKLNKEYMHDDILEEPLHEPIGSSNSTSNSSSVVDLQSSEDGGELNFYEDERHFFTDSGYPFYSQNKSFVKQICDLFISLFALNKANAGWLRGRAIITVLQQLLGSTIEKYIKVSIQKLRSEDQVFEAIVTFKNMLWGDNGLFERKRNETAEATRSEGERLRTEQLALTSLQRLFADTCGRVVGLRDSHEAAGRVHAMLQNPYLNASLLLEALDAILLDIICND | ||||||
Modified residue | 670 | Phosphoserine | ||||
Sequence: S | ||||||
Modified residue | 673 | Phosphoserine | ||||
Sequence: S | ||||||
Modified residue | 692 | Phosphoserine | ||||
Sequence: S |
Keywords
- PTM
Proteomic databases
PTM databases
Structure
Family & Domains
Features
Showing features for domain, coiled coil.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 85-273 | PXA | ||||
Sequence: NAQIGKELESIVNLIIKDFVQPWFTKIDKNSDAEFLKVIKWRLLQTLLVVKDKLMKNDSASLIVLKLLPIFNKHFSTFCDAREAVLSDLTLERHKSANIDLQIAVEFNKNYKIHKSLSLKPNALQKEIEKSIRKTVIGLLPHLFDNDELDSLLVFTLMTEVLTTCIISPLIFKFTDPDSWNLRIVSLSQ | ||||||
Coiled coil | 705-762 | |||||
Sequence: SNNFRDNIASLTISIDQIEKELELLRHLILKADLTNNQMQLKILKKSQRTLLKELEMK | ||||||
Domain | 782-905 | PX | ||||
Sequence: TKIYIRSYFSENSSNGLKEITYYIINIHHFNNGQVSSWDMARRYNEFFELNTYLKKNFRDLMRQLQDLFPSKVKMSLKYHVTKTLLYEERKQKLEKYLRELLSISEICEDNIFRRFLTDPTPFK |
Sequence similarities
Belongs to the sorting nexin family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,127
- Mass (Da)129,981
- Last updated2001-09-26 v3
- Checksum7C9177B87FDAF512
Sequence caution
Features
Showing features for sequence conflict.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Sequence conflict | 635 | in Ref. 3; CAA47014 | ||||
Sequence: H → D | ||||||
Sequence conflict | 772 | in Ref. 3; CAA47014 | ||||
Sequence: Q → R | ||||||
Sequence conflict | 899 | in Ref. 3; CAA47014 | ||||
Sequence: T → I | ||||||
Sequence conflict | 1063 | in Ref. 3; CAA47014 | ||||
Sequence: R → K | ||||||
Sequence conflict | 1081 | in Ref. 3; CAA47014 | ||||
Sequence: T → S | ||||||
Sequence conflict | 1096 | in Ref. 3; CAA47014 | ||||
Sequence: G → R |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
X80835 EMBL· GenBank· DDBJ | CAA56793.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
Z49210 EMBL· GenBank· DDBJ | CAA89114.1 EMBL· GenBank· DDBJ | Genomic DNA | Different initiation | |
X66371 EMBL· GenBank· DDBJ | CAA47014.1 EMBL· GenBank· DDBJ | Genomic DNA | Frameshift | |
X65783 EMBL· GenBank· DDBJ | CAA46664.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
BK006946 EMBL· GenBank· DDBJ | DAA09794.1 EMBL· GenBank· DDBJ | Genomic DNA |