Q01468 · 4OT1_PSEPU
- Protein2-hydroxymuconate tautomerase
- GenexylH
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids
- Protein existenceEvidence at protein level
- Annotation score4/5
Function
function
Catalyzes the ketonization of 2-hydroxymuconate stereoselectively to yield 2-oxo-3-hexenedioate.
Catalytic activity
- (2Z,4E)-2-hydroxyhexa-2,4-dienedioate = (3E)-2-oxohex-3-enedioate
Pathway
Xenobiotic degradation; toluene degradation.
Xenobiotic degradation; xylene degradation.
Features
Showing features for active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Active site | 2 | Proton acceptor; via imino nitrogen | ||||
Sequence: P |
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | isomerase activity | |
Biological Process | toluene catabolic process | |
Biological Process | xylene catabolic process |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended name2-hydroxymuconate tautomerase
- EC number
- Alternative names
Gene names
Encoded on
- Plasmid TOL pWW0
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Pseudomonadales > Pseudomonadaceae > Pseudomonas
Accessions
- Primary accessionQ01468
Phenotypes & Variants
Chemistry
PTM/Processing
Features
Showing features for initiator methionine, chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Initiator methionine | 1 | Removed | ||||
Sequence: M | ||||||
Chain | PRO_0000209514 | 2-63 | 2-hydroxymuconate tautomerase | |||
Sequence: PIAQIHILEGRSDEQKETLIREVSEAISRSLDAPLTSVRVIITEMAKGHFGIGGELASKVRR |
Interaction
Subunit
Homohexamer.
Structure
Sequence
- Sequence statusComplete
- Length63
- Mass (Da)6,942
- Last updated2007-01-23 v2
- Checksum23804AB94A126802
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
M95650 EMBL· GenBank· DDBJ | AAA26046.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
M94186 EMBL· GenBank· DDBJ | AAA25694.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AJ344068 EMBL· GenBank· DDBJ | CAC86799.1 EMBL· GenBank· DDBJ | Genomic DNA |