P9WNY4 · MMSB_MYCTO
- ProteinProbable 3-hydroxyisobutyrate dehydrogenase
- GenemmsB
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids294 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
Catalytic activity
- 3-hydroxy-2-methylpropanoate + NAD+ = 2-methyl-3-oxopropanoate + NADH + H+
Pathway
Amino-acid degradation; L-valine degradation.
Features
Showing features for binding site, active site.
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | 3-hydroxyisobutyrate dehydrogenase activity | |
Molecular Function | NAD binding | |
Molecular Function | NADP binding | |
Biological Process | valine catabolic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameProbable 3-hydroxyisobutyrate dehydrogenase
- EC number
- Short namesHIBADH
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Actinomycetota > Actinomycetes > Mycobacteriales > Mycobacteriaceae > Mycobacterium > Mycobacterium tuberculosis complex
Accessions
- Primary accessionP9WNY4
- Secondary accessions
Proteomes
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000427046 | 1-294 | Probable 3-hydroxyisobutyrate dehydrogenase | |||
Sequence: MTTIAFLGLGNMGAPMSANLVGAGHVVRGFDPAPTAASGAAAHGVAVFRSAPEAVAEADVVITMLPTGEVVRRCYTDVLAAARPATLFIDSSTISVTDAREVHALAESHGMLQLDAPVSGGVKGAAAATLAFMVGGDESTLRRARPVLEPMAGKIIHCGAAGAGQAAKVCNNMVLAVQQIAIAEAFVLAEKLGLSAQSLFDVITGATGNCWAVHTNCPVPGPVPTSPANNDFKPGFSTALMNKDLGLAMDAVAATGATAPLGSHAADIYAKFAADHADLDFSAVIHTLRARADA |
Structure
Sequence
- Sequence statusComplete
- Length294
- Mass (Da)29,679
- Last updated2014-04-16 v1
- Checksum68DEF129A8BA3E68
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AE000516 EMBL· GenBank· DDBJ | AAK45016.1 EMBL· GenBank· DDBJ | Genomic DNA |