Sequence and chromosomal mapping of the mouse homolog (Madh4) of the human DPC4/MADH4 gene.Anna C.H., Devereux T.R.Cited forNUCLEOTIDE SEQUENCE [MRNA]StrainA/JTissueLungCategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCMamm. Genome 8:443-444 (1997)Cited in1Mapped to4
No title available.Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.Cited forNUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]CategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)Submission Submitted to EMBL/GenBank/DDBJ databases (JUL-2005)Cited in99+20
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).The MGC Project TeamView abstractCited forNUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]TissueOlfactory epitheliumCategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCGenome Res. 14:2121-2127 (2004)Cited in99+99+
The transcriptional landscape of the mammalian genome.Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B.[...], Hayashizaki Y.View abstractCited forNUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 67-551StrainC57BL/6JTissueLungCategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCScience 309:1559-1563 (2005)Cited in99+16Mapped to99+
Identification of mZnf8, a mouse Kruppel-like transcriptional repressor, as a novel nuclear interaction partner of Smad1.Jiao K., Zhou Y., Hogan B.L.M.View abstractCited forINTERACTION WITH ZNF8CategoriesInteractionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCMol. Cell. Biol. 22:7633-7644 (2002)Cited in10Mapped to14
SMAD-mediated modulation of YY1 activity regulates the BMP response and cardiac-specific expression of a GATA4/5/6-dependent chick Nkx2.5 enhancer.Lee K.H., Evans S., Ruan T.Y., Lassar A.B.View abstractCited forFUNCTION, DNA-BINDING, IDENTIFICATION IN A COMPLEX WITH SMAD1 AND YY1CategoriesFunction, InteractionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCDevelopment 131:4709-4723 (2004)Cited in7
Smicl is a novel Smad interacting protein and cleavage and polyadenylation specificity factor associated protein.Collart C., Remacle J.E., Barabino S., van Grunsven L.A., Nelles L., Schellens A., Van de Putte T., Pype S., Huylebroeck D., Verschueren K.View abstractCited forINTERACTION WITH ZC3H3CategoriesInteractionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCGenes Cells 10:897-906 (2005)Cited in6Mapped to54
A tissue-specific atlas of mouse protein phosphorylation and expression.Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R., Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.View abstractCited forIDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]TissueLungCategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCCell 143:1174-1189 (2010)Cited in99+99+Mapped to6
The Crumbs complex couples cell density sensing to Hippo-dependent control of the TGF-beta-SMAD pathway.Varelas X., Samavarchi-Tehrani P., Narimatsu M., Weiss A., Cockburn K., Larsen B.G., Rossant J., Wrana J.L.View abstractCited forINTERACTION WITH SMAD2 AND SMAD3CategoriesInteractionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCDev. Cell 19:831-844 (2010)Cited in16Mapped to67
BMP signaling controls muscle mass.Sartori R., Schirwis E., Blaauw B., Bortolanza S., Zhao J., Enzo E., Stantzou A., Mouisel E., Toniolo L.[...], Sandri M.View abstractCited forFUNCTION, DISRUPTION PHENOTYPECategoriesFunction, Phenotypes & VariantsSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCNat. Genet. 45:1309-1318 (2013)Cited in5Mapped to15
Structure of Smad1 MH1/DNA complex reveals distinctive rearrangements of BMP and TGF-beta effectors.Baburajendran N., Palasingam P., Narasimhan K., Sun W., Prabhakar S., Jauch R., Kolatkar P.R.View abstractCited forX-RAY CRYSTALLOGRAPHY (2.71 ANGSTROMS) OF 9-140 IN COMPLEX WITH DNA, ZINC_BINDING SITES, SUBUNITCategoriesFunction, Interaction, StructureSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCNucleic Acids Res. 38:3477-3488 (2010)Cited in2Mapped to7
Genome-wide mapping of unselected transcripts from extraembryonic tissue of 7.5-day mouse embryos reveals enrichment in the t-complex and under- representation on the X chromosome.Ko M.S., Threat T.A., Wang X., Horton J.H., Cui Y., Wang X., Pryor E., Paris J., Wells-Smith J.[...], Nakashima H.View abstractCategoriesSequencesSourceMGI: 894293PubMedEurope PMCHum Mol Genet 7:1967-1978 (1998)Mapped to99+
Smad2 and Smad3 positively and negatively regulate TGF beta-dependent transcription through the forkhead DNA-binding protein FAST2.Labbe E., Silvestri C., Hoodless P.A., Wrana J.L., Attisano L.View abstractCategoriesInteractionSourceMGI: 894293PubMedEurope PMCMol. Cell 2:109-120 (1998)Cited in1Mapped to23
Smad2 signaling in extraembryonic tissues determines anterior-posterior polarity of the early mouse embryo.Waldrip W.R., Bikoff E.K., Hoodless P.A., Wrana J.L., Robertson E.J.View abstractCategoriesFunction, Expression, Subcellular LocationSourceMGI: 894293PubMedEurope PMCCell 92:797-808 (1998)Mapped to47
The tumor suppressor SMAD4/DPC4 is essential for epiblast proliferation and mesoderm induction in mice.Yang X., Li C., Xu X., Deng C.View abstractCategoriesPhenotypes & VariantsSourceMGI: 894293PubMedEurope PMCProc Natl Acad Sci U S A 95:3667-3672 (1998)Mapped to25
Intestinal tumorigenesis in compound mutant mice of both Dpc4 (Smad4) and Apc genes.Takaku K., Oshima M., Miyoshi H., Matsui M., Seldin M.F., Taketo M.M.View abstractCategoriesPhenotypes & VariantsSourceMGI: 894293PubMedEurope PMCCell 92:645-656 (1998)Mapped to20
The tumor suppressor gene Smad4/Dpc4 is required for gastrulation and later for anterior development of the mouse embryo.Sirard C., de la Pompa J.L., Elia A., Itie A., Mirtsos C., Cheung A., Hahn S., Wakeham A., Schwartz L.[...], Mak T.W.View abstractCategoriesPhenotypes & VariantsSourceMGI: 894293PubMedEurope PMCGenes Dev 12:107-119 (1998)Mapped to46
TGF-beta signalling from cell membrane to nucleus through SMAD proteins.Heldin C.H., Miyazono K., ten Dijke P.View abstractCategoriesPTM / Processing, Subcellular LocationSourceMGI: 894293PubMedEurope PMCNature 390:465-471 (1997)Mapped to31
Smad4 (homolog of human DPC4) and Smad2 (homolog of human JV18-1): candidates for murine lung tumor resistance and suppressor genes.Devereux T.R., Anna C.H., Patel A.C., White C.M., Festing M.F., You M.View abstractCategoriesSequencesSourceMGI: 894293PubMedEurope PMCCarcinogenesis 18:1751-1755 (1997)Cited in1Mapped to10
Smad4 and FAST-1 in the assembly of activin-responsive factor.Chen X., Weisberg E., Fridmacher V., Watanabe M., Naco G., Whitman M.View abstractCategoriesInteractionSourceMGI: 894293PubMedEurope PMCNature 389:85-89 (1997)Cited in1Mapped to10
Progenitor-like cells contributing to cellular heterogeneity in the nucleus pulposus are lost in intervertebral disc degeneration.Tan Z., Chen P., Dong X., Guo S., Leung V.Y.L., Cheung J.P.Y., Chan D., Richardson S.M., Hoyland J.A.[...], Cheah K.S.E.View abstractSourceMGI: 894293PubMedEurope PMCCell Rep 43:114342-114342 (2024)Mapped to86
Smad4 is essential for epiblast scaling and morphogenesis after implantation, but nonessential before implantation.Kruger R.E., Frum T., Brumm A.S., Hickey S.L., Niakan K.K., Aziz F., Shammami M.A., Roberts J.G., Ralston A.View abstractSourceMGI: 894293PubMedEurope PMCDevelopment 151:dev202377-dev202377 (2024)Mapped to36
Smad4 deficiency inhibits lung metastases through enhancing phagocytosis of lung interstitial macrophages.Song Y., Gu D., Gao N., Sa H., Wang R., Fang L., Yuan Z.View abstractAnnotationSmad4 deficiency inhibits lung metastases through enhancing phagocytosis of lung interstitial macrophages.SourceGeneRif: 17128PubMedEurope PMCBiochem Biophys Res Commun 715:150007-150007 (2024)Mapped to6
Epidermal Growth Factor-Like Repeats and Discoidin I-Like Domains 3 Deficiency Attenuates Dilated Cardiomyopathy by Inhibiting Ubiquitin Specific Peptidase 10 Dependent Smad4 Deubiquitination.Zhao M., Zheng Z., Peng S., Xu Y., Zhang J., Liu J., Pan W., Yin Z., Xu S.[...], Qin J.J.View abstractAnnotationEpidermal Growth Factor-Like Repeats and Discoidin I-Like Domains 3 Deficiency Attenuates Dilated Cardiomyopathy by Inhibiting Ubiquitin Specific Peptidase 10 Dependent Smad4 Deubiquitination.SourceGeneRif: 17128PubMedEurope PMCJ Am Heart Assoc 13:e031283-e031283 (2024)Mapped to27
Smad4 restricts injury-provoked biliary proliferation and carcinogenesis.Alexander W.B., Wang W., Hill M.A., O'Dell M.R., Ruffolo L.I., Guo B., Jackson K.M., Ullman N., Friedland S.C.[...], Hezel A.F.View abstractAnnotationSmad4 restricts injury-provoked biliary proliferation and carcinogenesis.SourceGeneRif: 17128, MGI: 894293PubMedEurope PMCDis Model Mech 17:dmm050358-dmm050358 (2024)Mapped to6