P96786 · FLID_HELPY

Function

function

Required for the morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end. Essential to colonize and establish infection in gastric mucosa as a result of its essential role in motility. Has effect on flaA gene transcription.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentbacterial-type flagellum
Cellular Componentbacterial-type flagellum filament cap
Cellular Componentbacterial-type flagellum hook
Cellular Componentextracellular region
Biological Processbacterial-type flagellum-dependent cell motility
Biological Processbacterial-type flagellum-dependent swarming motility
Biological Processcell adhesion

Names & Taxonomy

Protein names

  • Recommended name
    Flagellar hook-associated protein 2
  • Short names
    HAP2
  • Alternative names
    • Filament cap protein
    • Flagellar cap protein

Gene names

    • Name
      fliD
    • Ordered locus names
      HP_0752

Organism names

Accessions

  • Primary accession
    P96786

Proteomes

Phenotypes & Variants

Features

Showing features for natural variant.

TypeIDPosition(s)Description
Natural variant59in strain: KCTC 0217BP
Natural variant86in strain: KCTC 0217BP
Natural variant91in strain: KCTC 0217BP
Natural variant193in strain: KCTC 0217BP
Natural variant231in strain: KCTC 0217BP
Natural variant258in strain: KCTC 0217BP
Natural variant270in strain: KCTC 0217BP
Natural variant363in strain: KCTC 0217BP
Natural variant368in strain: KCTC 0217BP
Natural variant373in strain: KCTC 0217BP
Natural variant422in strain: KCTC 0217BP

Variants

We now provide the "Disease & Variants" viewer in its own tab.

The viewer provides 11 variants from UniProt as well as other sources including ClinVar and dbSNP.

Go to variant viewer

PTM/Processing

Features

Showing features for initiator methionine, chain.

TypeIDPosition(s)Description
Initiator methionine1Removed
ChainPRO_00001770192-685Flagellar hook-associated protein 2

Proteomic databases

Interaction

Subunit

Homopentamer.

Protein-protein interaction databases

Family & Domains

Features

Showing features for coiled coil.

TypeIDPosition(s)Description
Coiled coil618-647

Sequence similarities

Belongs to the FliD family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    685
  • Mass (Da)
    74,131
  • Last updated
    2007-01-23 v4
  • Checksum
    12D4F56473D047F6
MAIGSLSSLGLGSKVLNYDVIDKLKDADEKALIAPLDKKMEQNVEKQKALVEIKTLLSALKGPVKTLSDYSTYISRKSNVTGDALSASVGVGVPIQDIKVDVQNLAQGDINELGAKFSSRDDIFSQVDTTLKFYTQNKDYAVNIKAGMTLGDVAQSITDATNGEVMGIVMKTGGNDPYQLMVNTKNTGEDNRVYFGSHLQSTLTNKNALSLGVDGSGKSEVSLNLKGADGNMHEVPIMLELPESASIKQKNTAIQKAMEQALENDPNFKNLIANGDISIDTLHGGESLIINDRRGGNIEVKGSKAKELGFLQTTTQESDLLKSSRTIKEGKLEGVVSLNGQKLDLSALTKESNTSEENTDAIIQAINAKEGLSAFKNAEGKLVINSKTGMLTIKGEDALGKASLKDLGLNAGMVQSYEASQNTLFMSKNLQKASDSAFTYNGVSITRPTNEVNDVISGVNITLEQTTEPNKPAIISVSRDNQAIIDSLTEFVKAYNELIPKLDEDTRYDADTKIAGIFNGVGDIRAIRSSLNNVFSYSVHTDNGVESLMKYGLSLDDKGVMSLDEAKLSSALNSNPKATQDFFYGSDSKDMGGREIHQEGIFSKFNQVIANLIDGGNAKLKIYEDSLDRDAKSLTKDKENAQELLKTRYNIMAERFAAYDSQISKANQKFNSVQMMIDQAAAKKN

Features

Showing features for sequence conflict.

TypeIDPosition(s)Description
Sequence conflict654-685in Ref. 2; AAD07800

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
U82981
EMBL· GenBank· DDBJ
AAC35999.1
EMBL· GenBank· DDBJ
Genomic DNA
AE000511
EMBL· GenBank· DDBJ
AAD07800.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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