P93157 · ANX1_GOSHI
- ProteinAnnexin Gh1
- GeneAnnGh1
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids315 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score5/5
Function
function
Binds to phospholipid vesicles in a calcium-dependent manner in vitro (PubMed:16331990, PubMed:18441010).
Prefers phosphatidyl-serine containing membranes. May have a role in the membrane cytoskeleton scaffolding or exocytotic processes (PubMed:16331990).
May be involved in oxidative stress response (Probable)
Prefers phosphatidyl-serine containing membranes. May have a role in the membrane cytoskeleton scaffolding or exocytotic processes (PubMed:16331990).
May be involved in oxidative stress response (Probable)
Features
Showing features for binding site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 23 | Ca2+ 1 (UniProtKB | ChEBI) | ||||
Sequence: F | ||||||
Binding site | 25 | Ca2+ 1 (UniProtKB | ChEBI) | ||||
Sequence: G | ||||||
Binding site | 27 | Ca2+ 1 (UniProtKB | ChEBI) | ||||
Sequence: G | ||||||
Binding site | 67 | Ca2+ 1 (UniProtKB | ChEBI) | ||||
Sequence: E | ||||||
Binding site | 253 | Ca2+ 2 (UniProtKB | ChEBI) | ||||
Sequence: I | ||||||
Binding site | 255 | Ca2+ 2 (UniProtKB | ChEBI) | ||||
Sequence: R | ||||||
Binding site | 257 | Ca2+ 2 (UniProtKB | ChEBI) | ||||
Sequence: G | ||||||
Binding site | 295 | Ca2+ 3 (UniProtKB | ChEBI) | ||||
Sequence: V | ||||||
Binding site | 297 | Ca2+ 2 (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 298 | Ca2+ 3 (UniProtKB | ChEBI) | ||||
Sequence: T | ||||||
Binding site | 303 | Ca2+ 3 (UniProtKB | ChEBI) | ||||
Sequence: E |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Cellular Component | exocytic vesicle | |
Cellular Component | membrane | |
Cellular Component | plasma membrane | |
Molecular Function | calcium ion binding | |
Molecular Function | calcium-dependent phospholipid binding | |
Molecular Function | phosphatidylserine binding | |
Biological Process | calcium-ion regulated exocytosis | |
Biological Process | fruit ripening | |
Biological Process | protein trimerization | |
Biological Process | regulation of cellulose biosynthetic process | |
Biological Process | response to cold | |
Biological Process | response to heat | |
Biological Process | response to oxidative stress | |
Biological Process | response to salt stress | |
Biological Process | response to water deprivation | |
Biological Process | secretion by cell |
Keywords
- Ligand
Names & Taxonomy
Protein names
- Recommended nameAnnexin Gh1
- Short namesAnx(Gh1)
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Malvales > Malvaceae > Malvoideae > Gossypium
Accessions
- Primary accessionP93157
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000450599 | 1-315 | Annexin Gh1 | |||
Sequence: ATLTVPTTVPSVSEDCEQLRKAFSGWGTNEGLIIDILGHRNAEQRNLIRKTYAETYGEDLLKALDKELSNDFERLVLLWALDPAERDALLANEATKRWTSSNQVLMEIACTRSANQLLHARQAYHARYKKSLEEDVAHHTTGDFHKLLLPLVSSYRYEGEEVNMTLAKTEAKLLHEKISNKAYSDDDVIRVLATRSKAQINATLNHYKNEYGNDINKDLKADPKDEFLALLRSTVKCLVYPEKYFEKVLRLAINRRGTDEGALTRVVCTRAEVDLKVIADEYQRRNSVPLTRAIVKDTHGDYEKLLLVLAGHVEN |
Structure
Family & Domains
Features
Showing features for repeat.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Repeat | 10-81 | Annexin 1 | ||||
Sequence: PSVSEDCEQLRKAFSGWGTNEGLIIDILGHRNAEQRNLIRKTYAETYGEDLLKALDKELSNDFERLVLLWAL | ||||||
Repeat | 82-153 | Annexin 2 | ||||
Sequence: DPAERDALLANEATKRWTSSNQVLMEIACTRSANQLLHARQAYHARYKKSLEEDVAHHTTGDFHKLLLPLVS | ||||||
Repeat | 165-236 | Annexin 3 | ||||
Sequence: TLAKTEAKLLHEKISNKAYSDDDVIRVLATRSKAQINATLNHYKNEYGNDINKDLKADPKDEFLALLRSTVK | ||||||
Repeat | 240-311 | Annexin 4 | ||||
Sequence: YPEKYFEKVLRLAINRRGTDEGALTRVVCTRAEVDLKVIADEYQRRNSVPLTRAIVKDTHGDYEKLLLVLAG |
Domain
A pair of annexin repeats may form one binding site for calcium and phospholipid.
Sequence similarities
Belongs to the annexin family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusFragment
- Length315
- Mass (Da)35,824
- Last updated2001-10-01 v2
- Checksum653113C77AAAE980
Features
Showing features for non-terminal residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Non-terminal residue | 1 | |||||
Sequence: A |
Keywords
- Technical term