P93047 · HMGB3_ARATH
- ProteinHigh mobility group B protein 3
- GeneHMGB3
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids141 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score5/5
Function
function
Binds preferentially double-stranded DNA.
Features
Showing features for dna binding.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
DNA binding | 35-104 | HMG box | |||
GO annotations
all annotations | all molecular function | nucleotide binding | molecular_function | nucleic acid binding | dna binding | chromatin binding | dna-binding transcription factor activity | rna binding | cytoskeletal motor activity | catalytic activity | nuclease activity | signaling receptor binding | structural molecule activity | transporter activity | binding | protein binding | translation factor activity, rna binding | lipid binding | kinase activity | transferase activity | hydrolase activity | oxygen binding | enzyme regulator activity | carbohydrate binding | signaling receptor activity | translation regulator activity | transcription regulator activity | other molecular function | all biological process | carbohydrate metabolic process | generation of precursor metabolites and energy | nucleobase-containing compound metabolic process | dna metabolic process | translation | lipid metabolic process | transport | response to stress | cell cycle | cell communication | signal transduction | cell-cell signaling | multicellular organism development | circadian rhythm | biological_process | metabolic process | catabolic process | biosynthetic process | response to light stimulus | response to external stimulus | tropism | response to biotic stimulus | response to abiotic stimulus | response to endogenous stimulus | embryo development | post-embryonic development | fruit ripening | abscission | pollination | flower development | cellular process | programmed cell death | photosynthesis | cellular component organization | cell growth | protein metabolic process | cellular homeostasis | secondary metabolic process | reproductive process | cell differentiation | protein modification process | growth | epigenetic regulation of gene expression | response to chemical | anatomical structure development | regulation of molecular function | other biological process | all cellular component | cellular_component | extracellular region | cell wall | intracellular anatomical structure | nucleus | nuclear envelope | nucleoplasm | nucleolus | cytoplasm | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | cytosol | ribosome | cytoskeleton | plasma membrane | chloroplast | plastid | thylakoid | membrane | external encapsulating structure | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | chromatin | |
Cellular Component | cytosol | |
Cellular Component | nucleus | |
Molecular Function | chromatin binding | |
Molecular Function | DNA binding | |
Molecular Function | DNA-binding transcription factor activity | |
Molecular Function | structural constituent of chromatin | |
Biological Process | chromatin organization |
Keywords
- Molecular function
Names & Taxonomy
Protein names
- Recommended nameHigh mobility group B protein 3
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis
Accessions
- Primary accessionP93047
- Secondary accessions
Proteomes
Organism-specific databases
Genome annotation databases
Subcellular Location
PTM/Processing
Features
Showing features for chain, modified residue.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000399929 | 1-141 | High mobility group B protein 3 | ||
Modified residue | 122 | Phosphoserine | |||
Keywords
- PTM
Proteomic databases
PTM databases
Expression
Tissue specificity
Expressed in lateral roots, root tips, stems, cotyledons, leaves and flowers (excluding ovary and pedicels).
Induction
Up-regulated by cold stress, but down-regulated by drought and salt stress.
Gene expression databases
Structure
Family & Domains
Features
Showing features for compositional bias, region.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 1-16 | Basic and acidic residues | |||
Region | 1-40 | Disordered | |||
Region | 54-141 | Disordered | |||
Compositional bias | 74-119 | Basic and acidic residues | |||
Compositional bias | 120-141 | Acidic residues | |||
Sequence similarities
Belongs to the HMGB family.
Phylogenomic databases
Family and domain databases
Sequence & Isoforms
- Sequence statusComplete
This entry describes 3 isoforms produced by Alternative splicing.
P93047-1
This isoform has been chosen as the canonical sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.
- Name1
- Length141
- Mass (Da)15,681
- Last updated1997-05-01 v1
- MD5 Checksum029E80032BDF9C3F21F48B282357AC99
P93047-2
- Name2
- Differences from canonical
- 137-141: EEDDD → VRRR
P93047-3
- Name3
- Differences from canonical
- 108-141: EEGPKEDEESDKSVSEVNDEDDAEDGSEEEEDDD → VIALRKMRNLTSQFQRLTMRMMLRMAVKRRKTMIKKLKLW
Computationally mapped potential isoform sequences
There are 3 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A1P8ATG5 | A0A1P8ATG5_ARATH | HMGB3 | 133 | ||
A0A1P8ATJ7 | A0A1P8ATJ7_ARATH | HMGB3 | 99 | ||
A0A2H1ZEC3 | A0A2H1ZEC3_ARATH | HMGB3 | 98 |
Features
Showing features for compositional bias, alternative sequence.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 1-16 | Basic and acidic residues | |||
Compositional bias | 74-119 | Basic and acidic residues | |||
Alternative sequence | VSP_039942 | 108-141 | in isoform 3 | ||
Compositional bias | 120-141 | Acidic residues | |||
Alternative sequence | VSP_039943 | 137-141 | in isoform 2 | ||
Keywords
- Coding sequence diversity
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
Y14073 EMBL· GenBank· DDBJ | CAA74402.1 EMBL· GenBank· DDBJ | mRNA | ||
Y09482 EMBL· GenBank· DDBJ | CAA70691.1 EMBL· GenBank· DDBJ | mRNA | ||
AC069251 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
CP002684 EMBL· GenBank· DDBJ | AEE30009.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CP002684 EMBL· GenBank· DDBJ | AEE30010.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AF411789 EMBL· GenBank· DDBJ | AAL06479.1 EMBL· GenBank· DDBJ | mRNA | ||
AY097385 EMBL· GenBank· DDBJ | AAM19901.1 EMBL· GenBank· DDBJ | mRNA | ||
AY136309 EMBL· GenBank· DDBJ | AAM96975.1 EMBL· GenBank· DDBJ | mRNA | ||
BT000420 EMBL· GenBank· DDBJ | AAN15739.1 EMBL· GenBank· DDBJ | mRNA | ||
AY084848 EMBL· GenBank· DDBJ | AAM61413.1 EMBL· GenBank· DDBJ | mRNA |