P92558 · NU1M_ARATH

Function

function

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).

Miscellaneous

A stretch of 270 kb of the mitochondrial genome is duplicated within the centromere of chromosome 2 resulting in the duplication of the gene. The expression of the duplicated genes (At2g07785 and At2g07786) is not demonstrated. They are also probably not RNA edited and therefore differs in all the positions known to be edited.

Catalytic activity

GO annotations

all annotationsall molecular functionnucleotide bindingmolecular_functionnucleic acid bindingdna bindingchromatin bindingdna-binding transcription factor activityrna bindingcytoskeletal motor activitycatalytic activitynuclease activitysignaling receptor bindingstructural molecule activitytransporter activitybindingprotein bindingtranslation factor activity, rna bindinglipid bindingkinase activitytransferase activityhydrolase activityoxygen bindingenzyme regulator activitycarbohydrate bindingsignaling receptor activitytranslation regulator activitytranscription regulator activityother molecular functionall biological processcarbohydrate metabolic processgeneration of precursor metabolites and energynucleobase-containing compound metabolic processdna metabolic processtranslationlipid metabolic processtransportresponse to stresscell cyclecell communicationsignal transductioncell-cell signalingmulticellular organism developmentcircadian rhythmbiological_processmetabolic processcatabolic processbiosynthetic processresponse to light stimulusresponse to external stimulustropismresponse to biotic stimulusresponse to abiotic stimulusresponse to endogenous stimulusembryo developmentpost-embryonic developmentfruit ripeningabscissionpollinationflower developmentcellular processprogrammed cell deathphotosynthesiscellular component organizationcell growthprotein metabolic processcellular homeostasissecondary metabolic processreproductive processcell differentiationprotein modification processgrowthepigenetic regulation of gene expressionresponse to chemicalanatomical structure developmentregulation of molecular functionother biological processall cellular componentcellular_componentextracellular regioncell wallintracellular anatomical structurenucleusnuclear envelopenucleoplasmnucleoluscytoplasmmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuscytosolribosomecytoskeletonplasma membranechloroplastplastidthylakoidmembraneexternal encapsulating structureother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentmitochondrial respiratory chain complex I
Molecular FunctionNADH dehydrogenase (ubiquinone) activity
Biological Processaerobic respiration

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    NADH-ubiquinone oxidoreductase chain 1
  • EC number
  • Alternative names
    • NADH dehydrogenase subunit 1

Gene names

    • Name
      ND1
    • Synonyms
      NAD1
    • Ordered locus names
      AtMg00516/AtMg01120/AtMg01275
    • Ordered locus names
      At2g07785
    • Ordered locus names
      At2g07786

Encoded on

  • Mitochondrion

Organism names

  • Taxonomic identifier
  • Strains
    • cv. C24
    • cv. Columbia
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis

Accessions

  • Primary accession
    P92558
  • Secondary accessions
    • A0A2P2CLC3
    • Q42576

Proteomes

    • Identifier
    • Component
      Chromosome 2, Mitochondrion MT

Organism-specific databases

Subcellular Location

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane5-25Helical
Transmembrane68-88Helical
Transmembrane105-125Helical
Transmembrane144-164Helical
Transmembrane177-197Helical
Transmembrane227-247Helical
Transmembrane263-283Helical
Transmembrane302-322Helical

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00001173441-325NADH-ubiquinone oxidoreductase chain 1

Proteomic databases

Expression

Gene expression databases

Interaction

Subunit

Complex I is composed of at least 49 different subunits.

Protein-protein interaction databases

Family & Domains

Sequence similarities

Belongs to the complex I subunit 1 family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    325
  • Mass (Da)
    36,009
  • Last updated
    2023-09-13 v5
  • Checksum
    9659CCF300B7F926
MYIAVPAEILGIILPLLLGVAFLVLAERKVMAFVQRRKGPDVVGSFGLLQPLADGLKLILKEPISPSSANFFLFRMAPVATFMLSLVAWAVVPFDYGMVLSDLNIGLLYLFAISSLGVYGIIIAGWSSISKYAFLGALRSAAQMVSYEVSIGLILITVLICVGSCNLSEIVMAQKQIWFGIPLFPVLVMFFISCLAETNRAPFDLPEAEAELVAGYNVEYSSMGFALFFLGEYANMILMSGLCTLFFLGGWLPILDLPIFKKIPGSIWFSIKVLFFLFLYIWVRAAFPRYRYDQLMGLGWKVFLPLSLARVVPVSGLLVTFQWLP

Computationally mapped potential isoform sequences

There is 1 potential isoform mapped to this entry

View all
EntryEntry nameGene nameLength
Q3EC42Q3EC42_ARATHAt2g0778599

Features

Showing features for sequence conflict.

TypeIDPosition(s)Description
Sequence conflict129in Ref. 1; CAA57940

RNA Editing

Edited at positions 1
56
89
103
126
164
165
167
179
191
194
212
225
242
248
252
275
300
310
313
The initiator methionine is created by RNA editing

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
X82618
EMBL· GenBank· DDBJ
CAA57940.1
EMBL· GenBank· DDBJ
mRNA Sequence problems.
Y08501
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
BK010421
EMBL· GenBank· DDBJ
DAB41492.2
EMBL· GenBank· DDBJ
Genomic DNA
AC007729
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
CP002685
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.

Similar Proteins

Disclaimer

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