C. elegans midbodies are released, phagocytosed and undergo LC3-dependent degradation independent of macroautophagy.Fazeli G., Trinkwalder M., Irmisch L., Wehman A.M.View abstractCategoryPhenotypes & VariantsSourceWormBase: WBGene00004268PubMedEurope PMCJ Cell Sci 129:3721-3731 (2016)Mapped to17
DLK-1, SEK-3 and PMK-3 Are Required for the Life Extension Induced by Mitochondrial Bioenergetic Disruption in C. elegans.Munkacsy E., Khan M.H., Lane R.K., Borror M.B., Park J.H., Bokov A.F., Fisher A.L., Link C.D., Rea S.L.View abstractCategoryPhenotypes & VariantsSourceWormBase: WBGene00004268PubMedEurope PMCPLoS Genet 12:e1006133-e1006133 (2016)Mapped to99+
Small GTPases promote actin coat formation on microsporidian pathogens traversing the apical membrane of Caenorhabditis elegans intestinal cells.Szumowski S.C., Estes K.A., Popovich J.J., Botts M.R., Sek G., Troemel E.R.View abstractCategoryPhenotypes & VariantsSourceWormBase: WBGene00004268PubMedEurope PMCCell Microbiol 18:30-45 (2016)Mapped to4
Spatial and molecular cues for cell outgrowth during C. elegans uterine development.Ghosh S., Sternberg P.W.View abstractCategoryPhenotypes & VariantsSourceWormBase: WBGene00004268PubMedEurope PMCDev. Biol. 396:121-135 (2014)Cited in1Mapped to82
Inhibition of late endosomal maturation restores Wnt secretion in Caenorhabditis elegans vps-29 retromer mutants.Lorenowicz M.J., Macurkova M., Harterink M., Middelkoop T.C., de Groot R., Betist M.C., Korswagen H.C.View abstractCategoryPhenotypes & VariantsSourceWormBase: WBGene00004268PubMedEurope PMCCell Signal 26:19-31 (2014)Mapped to19
The million mutation project: a new approach to genetics in Caenorhabditis elegans.Thompson O., Edgley M., Strasbourger P., Flibotte S., Ewing B., Adair R., Au V., Chaudhry I., Fernando L.[...], Waterston R.H.View abstractCategoryPhenotypes & VariantsSourceWormBase: WBGene00004268PubMedEurope PMCGenome Res 23:1749-1762 (2013)Mapped to99+
Residual body removal during spermatogenesis in C. elegans requires genes that mediate cell corpse clearance.Huang J., Wang H., Chen Y., Wang X., Zhang H.View abstractCategoryExpression, Phenotypes & VariantsSourceWormBase: WBGene00004268, WormBase: WBGene00004268PubMedEurope PMCDevelopment 139:4613-4622 (2012)Mapped to4
Prediction of C. elegans longevity genes by human and worm longevity networks.Tacutu R., Shore D.E., Budovsky A., de Magalhaes J.P., Ruvkun G., Fraifeld V.E., Curran S.P.View abstractCategoryPhenotypes & VariantsSourceWormBase: WBGene00004268PubMedEurope PMCPLoS One 7:e48282-e48282 (2012)Mapped to99+
Caenorhabditis elegans screen reveals role of PAR-5 in RAB-11-recycling endosome positioning and apicobasal cell polarity.Winter J.F., Hoepfner S., Korn K., Farnung B.O., Bradshaw C.R., Marsico G., Volkmer M., Habermann B., Zerial M.View abstractCategoryPhenotypes & VariantsSourceWormBase: WBGene00004268PubMedEurope PMCNat. Cell Biol. 14:666-676 (2012)Cited in3Mapped to99+
Two PI 3-kinases and one PI 3-phosphatase together establish the cyclic waves of phagosomal PtdIns(3)P critical for the degradation of apoptotic cells.Lu N., Shen Q., Mahoney T.R., Neukomm L.J., Wang Y., Zhou Z.View abstractCategoryPhenotypes & VariantsSourceWormBase: WBGene00004268PubMedEurope PMCPLoS Biol. 10:E1001245-E1001245 (2012)Cited in4Mapped to2
A fitness assay for comparing RNAi effects across multiple C. elegans genotypes.Elvin M., Snoek L.B., Frejno M., Klemstein U., Kammenga J.E., Poulin G.B.View abstractCategoryPhenotypes & VariantsSourceWormBase: WBGene00004268PubMedEurope PMCBMC Genomics 12:510-510 (2011)Mapped to62
Disruption of endocytic pathway regulatory genes activates autophagy in C. elegans.Dwivedi M., Sung H., Shen H., Park B.J., Lee S.View abstractCategoryPhenotypes & VariantsSourceWormBase: WBGene00004268PubMedEurope PMCMol Cells 31:477-481 (2011)Mapped to14
The Arf GAP CNT-2 regulates the apoptotic fate in C. elegans asymmetric neuroblast divisions.Singhvi A., Teuliere J., Talavera K., Cordes S., Ou G., Vale R.D., Prasad B.C., Clark S.G., Garriga G.View abstractCategoryPhenotypes & VariantsSourceWormBase: WBGene00004268PubMedEurope PMCCurr. Biol. 21:948-954 (2011)Cited in2Mapped to16
Unusual regulation of a STAT protein by an SLC6 family transporter in C. elegans epidermal innate immunity.Dierking K., Polanowska J., Omi S., Engelmann I., Gut M., Lembo F., Ewbank J.J., Pujol N.View abstractCategoryPhenotypes & VariantsSourceWormBase: WBGene00004268PubMedEurope PMCCell Host Microbe 9:425-435 (2011)Cited in2Mapped to3
A high-resolution C. elegans essential gene network based on phenotypic profiling of a complex tissue.Green R.A., Kao H.L., Audhya A., Arur S., Mayers J.R., Fridolfsson H.N., Schulman M., Schloissnig S., Niessen S.[...], Oegema K.View abstractCategoryPhenotypes & VariantsSourceWormBase: WBGene00004268PubMedEurope PMCCell 145:470-482 (2011)Mapped to99+
A conserved role for SNX9-family members in the regulation of phagosome maturation during engulfment of apoptotic cells.Almendinger J., Doukoumetzidis K., Kinchen J.M., Kaech A., Ravichandran K.S., Hengartner M.O.View abstractCategoryPhenotypes & VariantsSourceWormBase: WBGene00004268PubMedEurope PMCPLoS ONE 6:E18325-E18325 (2011)Cited in1Mapped to5
RAB-5- and RAB-11-dependent vesicle-trafficking pathways are required for plasma membrane repair after attack by bacterial pore-forming toxin.Los F.C., Kao C.Y., Smitham J., McDonald K.L., Ha C., Peixoto C.A., Aroian R.V.View abstractAnnotationRAB-5 and RAB-11 are required for plasma membrane repair after attack by bacterial pore-forming toxin.CategoriesFunction, Phenotypes & VariantsSourceGeneRif: 172755, WormBase: WBGene00004268PubMedEurope PMCCell Host Microbe 9:147-157 (2011)Cited in1Mapped to5
A novel mitochondrial outer membrane protein, MOMA-1, that affects cristae morphology in Caenorhabditis elegans.Head B.P., Zulaika M., Ryazantsev S., van der Bliek A.M.View abstractCategoryPhenotypes & VariantsSourceWormBase: WBGene00004268PubMedEurope PMCMol. Biol. Cell 22:831-841 (2011)Cited in5Mapped to36
Intracellular organelles mediate cytoplasmic pulling force for centrosome centration in the Caenorhabditis elegans early embryo.Kimura K., Kimura A.View abstractCategoryPhenotypes & VariantsSourceWormBase: WBGene00004268PubMedEurope PMCProc Natl Acad Sci U S A 108:137-142 (2011)Mapped to8
Whole genome sequencing highlights genetic changes associated with laboratory domestication of C. elegans.Weber K.P., De S., Kozarewa I., Turner D.J., Babu M.M., de Bono M.View abstractCategoryPhenotypes & VariantsSourceWormBase: WBGene00004268PubMedEurope PMCPLoS One 5:e13922-e13922 (2010)Mapped to99+
Sequential action of Caenorhabditis elegans Rab GTPases regulates phagolysosome formation during apoptotic cell degradation.Guo P., Hu T., Zhang J., Jiang S., Wang X.View abstractSourceWormBase: WBGene00004268, WormBase: WBGene00004268PubMedEurope PMCProc Natl Acad Sci U S A 107:18016-18021 (2010)Mapped to16
EHBP-1 functions with RAB-10 during endocytic recycling in Caenorhabditis elegans.Shi A., Chen C.C., Banerjee R., Glodowski D., Audhya A., Rongo C., Grant B.D.View abstractCategoryPhenotypes & VariantsSourceWormBase: WBGene00004268PubMedEurope PMCMol. Biol. Cell 21:2930-2943 (2010)Cited in1Mapped to4
ccz-1 mediates the digestion of apoptotic corpses in C. elegans.Nieto C., Almendinger J., Gysi S., Gomez-Orte E., Kaech A., Hengartner M.O., Schnabel R., Moreno S., Cabello J.View abstractCategoryPhenotypes & VariantsSourceWormBase: WBGene00004268PubMedEurope PMCJ Cell Sci 123:2001-2007 (2010)Mapped to11
Identification of two evolutionarily conserved genes regulating processing of engulfed apoptotic cells.Kinchen J.M., Ravichandran K.S.View abstractCategoryPhenotypes & VariantsSourceWormBase: WBGene00004268PubMedEurope PMCNature 464:778-782 (2010)Mapped to26
Life-span extension by dietary restriction is mediated by NLP-7 signaling and coelomocyte endocytosis in C. elegans.Park S.K., Link C.D., Johnson T.E.View abstractCategoryPhenotypes & VariantsSourceWormBase: WBGene00004268PubMedEurope PMCFASEB J. 24:383-392 (2010)Cited in1Mapped to22