P87677 · P87677_FMDVO

Function

function

Lies on the inner surface of the capsid shell. After binding to the host receptor, the capsid undergoes conformational changes. Capsid protein VP4 is released, capsid protein VP1 N-terminus is externalized, and together, they shape a pore in the host membrane through which the viral genome is translocated into the host cell cytoplasm. After genome has been released, the channel shrinks.

GO annotations

AspectTerm
Cellular Componentcytoplasm
Cellular Componenthost cell cytoplasm
Cellular ComponentT=pseudo3 icosahedral viral capsid
Molecular Functionstructural molecule activity
Biological Processsymbiont entry into host cell
Biological Processvirion attachment to host cell

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Genome polyprotein

Organism names

Accessions

  • Primary accession
    P87677

Subcellular Location

Keywords

Structure

Family & Domains

Features

Showing features for region, domain.

Type
IDPosition(s)Description
Region1-20Disordered
Domain1-84Capsid protein VP4 Picornavirus
Region36-64Disordered
Domain110-273Picornavirus capsid
Domain335-489Picornavirus capsid

Sequence similarities

Belongs to the picornaviruses polyprotein family.

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    736
  • Mass (Da)
    80,608
  • Last updated
    1997-05-01 v1
  • Checksum
    D0533C8CD6B53F4B
GAGQSSPATGSQNQSGNTGSIINNYYMQQYQNSMDTQLGDNAISGGSNEGSTDTTSTHTTNTQNNDWFSKLASSAFSGLFGALLADKKTEETTLLEDRILTTRNGHTISTTQSSVGVTYGYATAEDFVSGPNTSGLETRVVQAERFFKTHLFDWVTSDPFGRCHLLELPTDHKGVYGSLTDSYAYMRNGWDVEVTAVGNQFNGGCLLVAMVPELCSIQKRELYQLTLFPHQFINPRTNMTAHITVPYVGVNRYDQYKVHKPWTLVVMVVAPLTVNTEGAPQIKVYANIAPTNVHVAGEFPSKEGIFPVACSDGYGGLVTTDPKTADPVYGKVFNPPRNLLPGRFTNLLDVAEACPTFLRFEGDVPYVTTKTDSDRVLAQFDMSLAANDMXNTFLAGLAQYYTQYSGTINLHFMFTGPTDAKAXYMIAYAPPGMEPPQTPEAAAHCIHAEWDTGLNSKFTFSIPYLSAADYAYTASDVAETTNVQGWVCLFQITHGKADGDALVVLASAGKDFELRLPVDARTETTSMGESADPVTATVENYGGDTQVQRRQHTDVSFIMDRFVKVTPQSSINTLDLMQIPSHTLVGALLRASTYYFSDLEIVVKHEGDLTWVPNGAPVQALGNTTNPTAYYKKPLTRLALPYTAPHRVLATVYNGECKYSSKAVPNVRGDLNVLEQKAARTLPTSFNYGAIKATRVTELLYRMKRAETYCPRPLLAIHPTDARHKQKIVAPVKQTL

Features

Showing features for non-terminal residue.

TypeIDPosition(s)Description
Non-terminal residue1
Non-terminal residue736

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
U82271
EMBL· GenBank· DDBJ
AAB39993.1
EMBL· GenBank· DDBJ
mRNA

Similar Proteins

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