P86934 · EF1A1_TRYB2

Function

function

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

Miscellaneous

The Kennedy pathway is the major route for phosphatidylethanolamine (PE) synthesis, as shown by reduced levels after using RNAi against the first two enzymes of the Kennedy pathway.

Features

Showing features for binding site.

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TypeIDPosition(s)Description
Binding site14-21GTP (UniProtKB | ChEBI)
Binding site91-95GTP (UniProtKB | ChEBI)
Binding site153-156GTP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functioncalmodulin binding
Molecular FunctionGTP binding
Molecular FunctionGTPase activity
Molecular FunctionmRNA binding
Molecular Functiontranslation elongation factor activity
Biological Processcalcium-mediated signaling
Biological Processmicrotubule-based process
Biological Processtranslation
Biological Processtranslational elongation

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Elongation factor 1-alpha 1
  • Short names
    EF-1-alpha 1

Gene names

    • Name
      TEF1
    • ORF names
      Tb10.70.5650

Organism names

Accessions

  • Primary accession
    P86934
  • Secondary accessions
    • P41166
    • Q38C32

Proteomes

Organism-specific databases

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain, modified residue.

TypeIDPosition(s)Description
ChainPRO_00004121201-449Elongation factor 1-alpha 1
Modified residue3625-glutamyl glycerylphosphorylethanolamine

Post-translational modification

Phosphatidylethanolamine (PE) is a direct precursor of the ethanolamine-phosphoglycerol (EPG) moiety.

Keywords

Proteomic databases

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for domain, region.

TypeIDPosition(s)Description
Domain5-230tr-type G
Region14-21G1
Region70-74G2
Region91-94G3
Region153-156G4
Region194-196G5

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    449
  • Mass (Da)
    49,106
  • Last updated
    2011-07-27 v1
  • Checksum
    D597D39CE436660D
MGKEKVHMNLVVVGHVDAGKSTATGHLIYKCGGIDKRTIEKFEKEAADIGKASFKYAWVLDKLKAERERGITIDIALWKFESPKSVFTIIDAPGHRDFIKNMITGTSQADAAILIIASAQGEFEAGISKDGQTREHALLAFTLGVKQMVVCCNKMDDKTVNYGQERYDEIVKEVSAYIKKVGYNVEKVRFVPISGWQGDNMIEKSEKMPWYKGPTLLEALDMLEPPVRPSDKPLRLPLQDVYKIGGIGTVPVGRVETGVMKPGDVVTFAPANVTTEVKSIEMHHEQLAEATPGDNVGFNVKNVSVKDIRRGNVCGNTKNDPPKEAADFTAQVIILNHPGQIGNGYAPVLDCHTSHIACKFAEIESKIDRRSGKELEKAPKSIKSGDAAIVRMVPQKPMCVEVFNDYAPLGRFAVRDMRQTVAVGIIKAVTKKDGSGGKVTKAAVKASKK

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CM000208
EMBL· GenBank· DDBJ
EAN77638.1
EMBL· GenBank· DDBJ
Genomic DNA
L25868
EMBL· GenBank· DDBJ
AAA16602.1
EMBL· GenBank· DDBJ
Unassigned DNA

Genome annotation databases

Similar Proteins

Disclaimer

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