Identification and cloning of human mitochondrial translational release factor 1 and the ribosome recycling factor.Zhang Y., Spremulli L.L.View abstractAnnotationPathwayCategoryFunctionSourceReactome: R-HSA-5368254PubMedEurope PMCBiochim. Biophys. Acta 1443:245-250 (1998)Cited in2Mapped to86
Mechanistic studies of the translational elongation cycle in mammalian mitochondria.Woriax V.L., Bullard J.M., Ma L., Yokogawa T., Spremulli L.L.View abstractAnnotationPathwayCategoryFunctionSourceReactome: R-HSA-5368254PubMedEurope PMCBiochim Biophys Acta 1352:91-101 (1997)Mapped to86
Structural basis of LRPPRC-SLIRP-dependent translation by the mitoribosome.Singh V., Moran J.C., Itoh Y., Soto I.C., Fontanesi F., Couvillion M., Huynen M.A., Churchman L.S., Barrientos A., Amunts A.View abstractCategoryStructureSourcePDB: 8ANYPubMedEurope PMCNat Struct Mol Biol 0:0-0 (2024)Mapped to84
GTPBP8 plays a role in mitoribosome formation in human mitochondria.Cipullo M., Valentin Gese G., Gopalakrishna S., Krueger A., Lobo V., Pirozhkova M.A., Marks J., Palenikova P., Shiriaev D.[...], Rorbach J.View abstractCategoryStructureSourcePDB: 8QRK, PDB: 8QRL, PDB: 8QRM, PDB: 8QRNPubMedEurope PMCNat Commun 15:5664-5664 (2024)Mapped to85
Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline.Li X., Wang M., Denk T., Buschauer R., Li Y., Beckmann R., Cheng J.View abstractCategoryStructureSourcePDB: 8K2A, PDB: 8XT0, PDB: 8XT2PubMedEurope PMCNat Commun 15:5481-5481 (2024)Cited in3Mapped to99+
Mitoribosome structure with cofactors and modifications reveals mechanism of ligand binding and interactions with L1 stalk.Singh V., Itoh Y., Del'Olio S., Hassan A., Naschberger A., Flygaard R.K., Nobe Y., Izumikawa K., Aibara S.[...], Amunts A.View abstractCategoryStructureSourcePDB: 7QI4, PDB: 7QI5, PDB: 7QI6PubMedEurope PMCNat Commun 15:4272-4272 (2024)Cited in1Mapped to81
Structure of mitoribosome reveals mechanism of mRNA binding, tRNA interactions with L1 stalk, roles of cofactors and rRNA modifications.Singh V., Itoh Y., Del'Olio S., Hassan A., Naschberger A., Flygaard R.K., Nobe Y., Izumikawa K., Aibara S.[...], Amunts A.View abstractCategoryStructureSourcePDB: 7QI4, PDB: 7QI5, PDB: 7QI6PubMedEurope PMCbioRxiv 0:2023.05.24.542018-2023.05.24.542018 (2023)Mapped to82
Molecular basis of translation termination at noncanonical stop codons in human mitochondria.Saurer M., Leibundgut M., Nadimpalli H.P., Scaiola A., Schoenhut T., Lee R.G., Siira S.J., Rackham O., Dreos R.[...], Ban N.View abstractCategoryStructureSourcePDB: 8OIR, PDB: 8OISPubMedEurope PMCScience 380:531-536 (2023)Cited in384Mapped to84
Principles of mitoribosomal small subunit assembly in eukaryotes.Harper N.J., Burnside C., Klinge S.View abstractCategoryStructureSourcePDB: 8CSP, PDB: 8CSQ, PDB: 8CSR, PDB: 8CSS, PDB: 8CST, PDB: 8CSUPubMedEurope PMCNature 614:175-181 (2023)Cited in5Mapped to64
Mechanism of mitoribosomal small subunit biogenesis and preinitiation.Itoh Y., Khawaja A., Laptev I., Cipullo M., Atanassov I., Sergiev P., Rorbach J., Amunts A.View abstractCategoryStructureSourcePDB: 7PNX, PDB: 7PNY, PDB: 7PNZ, PDB: 7PO0, PDB: 7PO1, PDB: 7PO2, PDB: 7PO3PubMedEurope PMCNature 606:603-608 (2022)Cited in1Mapped to99+
Distinct mechanisms of the human mitoribosome recycling and antibiotic resistance.Koripella R.K., Deep A., Agrawal E.K., Keshavan P., Banavali N.K., Agrawal R.K.View abstractCategoryStructureSourcePDB: 7L08PubMedEurope PMCNat Commun 12:3607-3607 (2021)Cited in3Mapped to80
Mechanism of membrane-tethered mitochondrial protein synthesis.Itoh Y., Andrell J., Choi A., Richter U., Maiti P., Best R.B., Barrientos A., Battersby B.J., Amunts A.View abstractCategoryStructureSourcePDB: 6ZM5, PDB: 6ZM6PubMedEurope PMCScience 371:846-849 (2021)Cited in2Mapped to84
Elongational stalling activates mitoribosome-associated quality control.Desai N., Yang H., Chandrasekaran V., Kazi R., Minczuk M., Ramakrishnan V.View abstractCategoryStructureSourcePDB: 7A5F, PDB: 7A5G, PDB: 7A5I, PDB: 7A5KPubMedEurope PMCScience 370:1105-1110 (2020)Cited in43Mapped to86
Structural basis of mitochondrial translation.Aibara S., Singh V., Modelska A., Amunts A.View abstractCategoryStructureSourcePDB: 6ZS9, PDB: 6ZSA, PDB: 6ZSB, PDB: 6ZSC, PDB: 6ZSD, PDB: 6ZSE, PDB: 6ZSG, PDB: 7OG4PubMedEurope PMCElife 9:e58362-e58362 (2020)Cited in3Mapped to82
Structures of the human mitochondrial ribosome bound to EF-G1 reveal distinct features of mitochondrial translation elongation.Koripella R.K., Sharma M.R., Bhargava K., Datta P.P., Kaushal P.S., Keshavan P., Spremulli L.L., Banavali N.K., Agrawal R.K.View abstractCategoryStructureSourcePDB: 6VLZ, PDB: 6VMIPubMedEurope PMCNat Commun 11:3830-3830 (2020)Cited in3Mapped to84
Structural insights into unique features of the human mitochondrial ribosome recycling.Koripella R.K., Sharma M.R., Risteff P., Keshavan P., Agrawal R.K.View abstractCategoryStructureSourcePDB: 6NU2, PDB: 6NU3PubMedEurope PMCProc Natl Acad Sci U S A 116:8283-8288 (2019)Cited in1Mapped to81
A human interactome in three quantitative dimensions organized by stoichiometries and abundances.Hein M.Y., Hubner N.C., Poser I., Cox J., Nagaraj N., Toyoda Y., Gak I.A., Weisswange I., Mansfeld J.[...], Mann M.View abstractCategoryInteractionSourceIntAct: P82932PubMedEurope PMCCell 163:712-723 (2015)Mapped to99+
A proteome-scale map of the human interactome network.Rolland T., Tasan M., Charloteaux B., Pevzner S.J., Zhong Q., Sahni N., Yi S., Lemmens I., Fontanillo C.[...], Vidal M.View abstractCategoryInteractionSourceIntAct: P82932PubMedEurope PMCCell 159:1212-1226 (2014)Mapped to99+
Ribosome rescue and translation termination at non-standard stop codons by ICT1 in mammalian mitochondria.Akabane S., Ueda T., Nierhaus K.H., Takeuchi N.View abstractAnnotationPathwayCategoryFunctionSourceReactome: R-HSA-5368254PubMedEurope PMCPLoS Genet 10:e1004616-e1004616 (2014)Mapped to86
Cryo-EM structure of the small subunit of the mammalian mitochondrial ribosome.Kaushal P.S., Sharma M.R., Booth T.M., Haque E.M., Tung C.S., Sanbonmatsu K.Y., Spremulli L.L., Agrawal R.K.View abstractAnnotationPathwayCategoryFunctionSourceReactome: R-HSA-5368254PubMedEurope PMCProc. Natl. Acad. Sci. U.S.A. 111:7284-7289 (2014)Cited in252Mapped to91
Architecture of the large subunit of the mammalian mitochondrial ribosome.Greber B.J., Boehringer D., Leitner A., Bieri P., Voigts-Hoffmann F., Erzberger J.P., Leibundgut M., Aebersold R., Ban N.View abstractAnnotationPathwayCategoryFunctionSourceReactome: R-HSA-5368254PubMedEurope PMCNature 505:515-519 (2014)Cited in25Mapped to87
Codon-reading specificities of mitochondrial release factors and translation termination at non-standard stop codons.Lind C., Sund J., Aqvist J.View abstractAnnotationPathwayCategoryFunctionSourceReactome: R-HSA-5368254PubMedEurope PMCNat. Commun. 4:2940-2940 (2013)Cited in1Mapped to85
The protein interaction landscape of the human CMGC kinase group.Varjosalo M., Keskitalo S., Van Drogen A., Nurkkala H., Vichalkovski A., Aebersold R., Gstaiger M.View abstractCategoryInteractionSourceIntAct: P82932PubMedEurope PMCCell Rep 3:1306-1320 (2013)Mapped to99+
Structure based hypothesis of a mitochondrial ribosome rescue mechanism.Huynen M.A., Duarte I., Chrzanowska-Lightowlers Z.M., Nabuurs S.B.View abstractAnnotationPathwayCategoryFunctionSourceReactome: R-HSA-5368254PubMedEurope PMCBiol. Direct 7:14-14 (2012)Cited in1Mapped to86
Purification and characterization of elongation factor G from bovine liver mitochondria.Chung H.K., Spremulli L.L.View abstractAnnotationPathwayCategoryFunctionSourceReactome: R-HSA-5368254PubMedEurope PMCJ Biol Chem 265:21000-21004 (1990)Mapped to86