P79001 · PGPS1_SACPS

Function

function

Essential for the viability of mitochondrial petite mutant. Catalyzes the committed step to the synthesis of the acidic phospholipids (By similarity).

Catalytic activity

Pathway

Phospholipid metabolism; phosphatidylglycerol biosynthesis; phosphatidylglycerol from CDP-diacylglycerol: step 1/2.

Features

Showing features for binding site, active site.

152150100150200250300350400450500
TypeIDPosition(s)Description
Binding site91-98ATP (UniProtKB | ChEBI)
Active site182
Active site184
Active site189

GO annotations

AspectTerm
Cellular Componentmitochondrion
Molecular FunctionATP binding
Molecular FunctionCDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity
Biological Processcardiolipin biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase
  • EC number
  • Alternative names
    • Phosphatidylglycerophosphate synthase (PGP synthase)

Gene names

    • Name
      PGS1
    • Synonyms
      PEL1, YCLUN3W

Organism names

Accessions

  • Primary accession
    P79001

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00000568261-521CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase

Structure

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain177-203PLD phosphodiesterase 1
Domain419-457PLD phosphodiesterase 2

Sequence similarities

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    521
  • Mass (Da)
    59,354
  • Last updated
    1997-05-01 v1
  • Checksum
    1E28ABDDB2231302
MTTRLLQLTRPHYRLLSSPFRKSSIIQRQMSASSPSPANSYLNMITKSLQHNLQTWFHFEPNEIDIIESPSHFYDLLKSKISSSQKRIFIASLYLGKSETELIDCISQALSKNPDLKVSFLLDGLRGTRELPSTCSATLLSSLVAKYGSERVDCRLYKTPAYHGWKKIVVPKRFNEGLGLQHMKIYGFDNEIILSGANLSNDYFTNRQDRYYLFKSANFANYYFKLHQLISSFSYQIVKPKVAGNVNIIWPDSNPTIEPMKNKRKFLREASQLLENFLQISKHNQPISPPGQFSTIVYPISQFTPLFPKYNDKSTEKSTILSLLSNIKNTSISWTFTAGYFNILPEIKANLLATPVTEANVITASPFANGFYQSKGVSSNLPGAYLYLSKKFLQDVSRYNKDQAITLREWQRGVVNKPNGWSYHAKGIWISSRDNNDSDSWKPFITVIGSSNYTRRAYSLDLESNALIITKDEELRNKMKGELNDLLQYTKPVTLEDFKSDPERHVGTGVKIATSVLGKKL

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
Z86109
EMBL· GenBank· DDBJ
CAB06796.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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