P77499 · SUFC_ECOLI

Function

function

Has low ATPase activity. The SufBCD complex acts synergistically with SufE to stimulate the cysteine desulfurase activity of SufS. The SufBCD complex contributes to the assembly or repair of oxygen-labile iron-sulfur clusters under oxidative stress. May facilitate iron uptake from extracellular iron chelators under iron limitation.

Kinetics

KM SUBSTRATE pH TEMPERATURE[C] NOTES EVIDENCE
0.29 mMATP
Vmax pH TEMPERATURE[C] NOTES EVIDENCE
4.45 μmol/min/mg

Features

Showing features for binding site.

124820406080100120140160180200220240
TypeIDPosition(s)Description
Binding site34-41ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytosol
Cellular Componentiron-sulfur cluster assembly complex
Molecular FunctionATP binding
Molecular FunctionATP hydrolysis activity
Biological Processiron-sulfur cluster assembly
Biological Processresponse to radiation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Probable ATP-dependent transporter SufC

Gene names

    • Name
      sufC
    • Synonyms
      ynhD
    • Ordered locus names
      b1682, JW1672

Organism names

  • Taxonomic identifier
  • Strains
    • K12 / W3110 / ATCC 27325 / DSM 5911
    • K12 / MG1655 / ATCC 47076
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Enterobacteriaceae > Escherichia

Accessions

  • Primary accession
    P77499

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00000929801-248Probable ATP-dependent transporter SufC

Proteomic databases

Interaction

Subunit

Part of the SufBCD complex that contains SufB, SufC and SufD. Interacts directly with SufB and SufD. Interacts with SufA (PubMed:19810706).

Binary interactions

TypeEntry 1Entry 2Number of experimentsIntAct
BINARY P77499sufA P776675EBI-561601, EBI-1125011
BINARY P77499sufB P7752215EBI-561601, EBI-562758
BINARY P77499sufD P776899EBI-561601, EBI-562751

Complex viewer

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain2-246ABC transporter

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    248
  • Mass (Da)
    27,582
  • Last updated
    1997-02-01 v1
  • Checksum
    78FB1108E1850DF9
MLSIKDLHVSVEDKAILRGLSLDVHPGEVHAIMGPNGSGKSTLSATLAGREDYEVTGGTVEFKGKDLLALSPEDRAGEGIFMAFQYPVEIPGVSNQFFLQTALNAVRSYRGQETLDRFDFQDLMEEKIALLKMPEDLLTRSVNVGFSGGEKKRNDILQMAVLEPELCILDESDSGLDIDALKVVADGVNSLRDGKRSFIIVTHYQRILDYIKPDYVHVLYQGRIVKSGDFTLVKQLEEQGYGWLTEQQ

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
U00096
EMBL· GenBank· DDBJ
AAC74752.1
EMBL· GenBank· DDBJ
Genomic DNA
AP009048
EMBL· GenBank· DDBJ
BAA15455.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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