P75510 · SYW_MYCPN
- ProteinTryptophan--tRNA ligase
- GenetrpS
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids346 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score3/5
Function
function
Catalyzes the attachment of tryptophan to tRNA(Trp).
Catalytic activity
- tRNA(Trp) + L-tryptophan + ATP = L-tryptophanyl-tRNA(Trp) + AMP + diphosphate + H+
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 10-12 | ATP (UniProtKB | ChEBI) | |||
Binding site | 18-19 | ATP (UniProtKB | ChEBI) | |||
Binding site | 140 | L-tryptophan (UniProtKB | ChEBI) | |||
Binding site | 152-154 | ATP (UniProtKB | ChEBI) | |||
Binding site | 191 | ATP (UniProtKB | ChEBI) | |||
Binding site | 200-204 | ATP (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | ATP binding | |
Molecular Function | tryptophan-tRNA ligase activity | |
Biological Process | tryptophanyl-tRNA aminoacylation |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameTryptophan--tRNA ligase
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Mycoplasmatota > Mycoplasmoidales > Mycoplasmoidaceae > Mycoplasmoides
Accessions
- Primary accessionP75510
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000136648 | 1-346 | Tryptophan--tRNA ligase | ||
Structure
Family & Domains
Features
Showing features for motif.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Motif | 11-19 | 'HIGH' region | |||
Motif | 200-204 | 'KMSKS' region | |||
Sequence similarities
Belongs to the class-I aminoacyl-tRNA synthetase family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length346
- Mass (Da)39,079
- Last updated1997-02-01 v1
- MD5 Checksum6F43C9B13579FD1FC92EF63CD9DB2B07
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
U00089 EMBL· GenBank· DDBJ | AAB96216.1 EMBL· GenBank· DDBJ | Genomic DNA |