P74250 · GPX1_SYNY3

Function

function

Hydroperoxy fatty acid reductase essential for the removal of lipid hydroperoxides under normal and stress conditions, leading to the protection of membrane integrity.

Catalytic activity

Activity regulation

Mercaptosuccinate, pCMB, and nethylmaleimide act as inhibitors of the catalytic activity.

Kinetics

KM SUBSTRATE pH TEMPERATURE[C] NOTES EVIDENCE
83.1 μMNADPH
215 μMalpha-linolenic acid hydroperoxide

pH Dependence

Optimum pH is 8.2.

Temperature Dependence

Optimum temperature is 37 degrees Celsius.

Features

Showing features for active site.

TypeIDPosition(s)Description
Active site41

GO annotations

AspectTerm
Molecular Functionperoxidase activity
Biological Processcellular response to oxidative stress

Keywords

Enzyme and pathway databases

Protein family/group databases

Names & Taxonomy

Protein names

  • Recommended name
    Hydroperoxy fatty acid reductase gpx1
  • EC number

Gene names

    • Name
      gpx1
    • Ordered locus names
      slr1171

Organism names

Accessions

  • Primary accession
    P74250

Proteomes

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00000666631-169Hydroperoxy fatty acid reductase gpx1

Proteomic databases

Expression

Induction

High light, methylviologen, t-butyl hydroperoxide, and salt stress conditions increase the expression level.

Interaction

Subunit

Monomer.

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the glutathione peroxidase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    169
  • Mass (Da)
    18,452
  • Last updated
    1997-02-01 v1
  • Checksum
    0DC382089FCE39E2
MTAQANNTIYGFSANALDGSPVALRDFEGKVLLIVNTASQCGFTPQYQGLQALYNRFGDRGFTVLGFPCNQFGQQEPGGSGEIKNFCETRYGVTFPLFEKVEVNGPNAHPLFKFLTAASPGMAIPFLGGAEDIKWNFTKFLVDRQGKVVKRYGSIAKPDEIAADIEKLL

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
BA000022
EMBL· GenBank· DDBJ
BAA18344.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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