P70478 · APC_RAT

  • Protein
    Adenomatous polyposis coli protein
  • Gene
    Apc
  • Status
    UniProtKB reviewed (Swiss-Prot)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    5/5

Function

function

Tumor suppressor. Promotes rapid degradation of CTNNB1 and participates in Wnt signaling as a negative regulator. APC activity is correlated with its phosphorylation state. Activates the GEF activity of SPATA13 and ARHGEF4. Plays a role in hepatocyte growth factor (HGF)-induced cell migration (By similarity).
Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells (By similarity).
Associates with both microtubules and actin filaments, components of the cytoskeleton (By similarity).
Plays a role in mediating the organization of F-actin into ordered bundles (By similarity).
Functions downstream of Rho GTPases and DIAPH1 to selectively stabilize microtubules (By similarity).
Acts as a mediator of ERBB2-dependent stabilization of microtubules at the cell cortex. It is required for the localization of MACF1 to the cell membrane and this localization of MACF1 is critical for its function in microtubule stabilization (By similarity).

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentadherens junction
Cellular Componentaxon
Cellular Componentaxonal growth cone
Cellular Componentbeta-catenin destruction complex
Cellular Componentbicellular tight junction
Cellular Componentcatenin complex
Cellular Componentcell body fiber
Cellular Componentcell cortex
Cellular Componentcell projection
Cellular Componentcell projection membrane
Cellular Componentcentrosome
Cellular Componentcytoplasm
Cellular Componentdendrite
Cellular Componentglutamatergic synapse
Cellular Componentgrowth cone
Cellular Componentkinetochore
Cellular Componentlamellipodium
Cellular Componentlateral plasma membrane
Cellular Componentmicrotubule
Cellular Componentmicrotubule cytoskeleton
Cellular Componentneuron projection terminus
Cellular Componentneuronal cell body
Cellular Componentnuclear membrane
Cellular Componentnucleus
Cellular Componentperinuclear region of cytoplasm
Cellular Componentplasma membrane
Cellular Componentpostsynapse
Cellular Componentprotein-containing complex
Cellular Componentruffle membrane
Cellular ComponentScrib-APC-beta-catenin complex
Cellular Componentsynaptic vesicle membrane
Molecular Functionbeta-catenin binding
Molecular Functiondynein complex binding
Molecular Functiongamma-catenin binding
Molecular Functionmicrotubule binding
Molecular Functionmicrotubule plus-end binding
Molecular Functionprotease binding
Molecular Functionprotein kinase binding
Molecular Functionprotein kinase regulator activity
Molecular Functionprotein-containing complex binding
Molecular Functionubiquitin protein ligase binding
Biological Processacinar cell proliferation
Biological Processanterior/posterior pattern specification
Biological Processapoptotic process
Biological Processaxis specification
Biological Processaxonogenesis
Biological Processcanonical Wnt signaling pathway
Biological Processcanonical Wnt signaling pathway involved in negative regulation of apoptotic process
Biological Processcanonical Wnt signaling pathway involved in positive regulation of apoptotic process
Biological Processcell adhesion
Biological Processcell division
Biological Processcell fate specification
Biological Processcell migration
Biological Processcell population proliferation
Biological Processcellular response to nerve growth factor stimulus
Biological Processchromosome organization
Biological Processcytoplasmic microtubule organization
Biological ProcessDNA damage response
Biological Processdorsal/ventral pattern formation
Biological Processendothelial cell proliferation
Biological Processepithelial cell apoptotic process
Biological Processepithelial cell proliferation
Biological Processepithelial cell proliferation involved in prostate gland development
Biological Processestablishment or maintenance of cell polarity
Biological Processfibroblast apoptotic process
Biological Processfibroblast migration
Biological Processhair follicle development
Biological Processinsulin receptor signaling pathway
Biological Processkidney development
Biological ProcessMAPK cascade
Biological Processmetaphase/anaphase transition of mitotic cell cycle
Biological Processmicrotubule depolymerization
Biological Processmicrotubule polymerization
Biological Processmitotic cytokinesis
Biological Processmitotic spindle assembly checkpoint signaling
Biological Processmuscle cell cellular homeostasis
Biological Processnegative regulation of acinar cell proliferation
Biological Processnegative regulation of apoptotic process
Biological Processnegative regulation of canonical Wnt signaling pathway
Biological Processnegative regulation of cardiac muscle cell proliferation
Biological Processnegative regulation of cell cycle G1/S phase transition
Biological Processnegative regulation of cell population proliferation
Biological Processnegative regulation of cyclin-dependent protein serine/threonine kinase activity
Biological Processnegative regulation of endothelial cell proliferation
Biological Processnegative regulation of epithelial cell apoptotic process
Biological Processnegative regulation of epithelial cell proliferation
Biological Processnegative regulation of epithelial cell proliferation involved in prostate gland development
Biological Processnegative regulation of G1/S transition of mitotic cell cycle
Biological Processnegative regulation of MAPK cascade
Biological Processnegative regulation of microtubule depolymerization
Biological Processnegative regulation of odontogenesis
Biological Processnegative regulation of Wnt signaling pathway
Biological Processnervous system development
Biological Processneuron projection development
Biological Processodontogenesis
Biological Processpancreas development
Biological Processpattern specification process
Biological Processpositive regulation of apoptotic process
Biological Processpositive regulation of cell adhesion
Biological Processpositive regulation of cell differentiation
Biological Processpositive regulation of cell division
Biological Processpositive regulation of cell migration
Biological Processpositive regulation of cold-induced thermogenesis
Biological Processpositive regulation of fibroblast apoptotic process
Biological Processpositive regulation of fibroblast migration
Biological Processpositive regulation of microtubule polymerization
Biological Processpositive regulation of protein catabolic process
Biological Processpositive regulation of protein localization to centrosome
Biological Processpositive regulation of pseudopodium assembly
Biological Processprotein catabolic process
Biological Processprotein-containing complex assembly
Biological Processproximal/distal pattern formation
Biological Processregulation of attachment of spindle microtubules to kinetochore
Biological Processregulation of cell cycle
Biological Processregulation of cell differentiation
Biological Processregulation of cell migration
Biological Processregulation of epithelial cell differentiation
Biological Processregulation of epithelial cell migration
Biological Processregulation of glutamate metabolic process
Biological Processregulation of metabolic process
Biological Processregulation of microtubule-based movement
Biological Processregulation of microtubule-based process
Biological Processregulation of osteoblast differentiation
Biological Processregulation of osteoclast differentiation
Biological Processresponse to alcohol
Biological Processresponse to xenobiotic stimulus
Biological Processretina development in camera-type eye
Biological Processskin development
Biological Processsomatic stem cell population maintenance
Biological Processstem cell population maintenance
Biological ProcessT cell differentiation in thymus
Biological Processthymus development
Biological ProcessWnt signaling pathway

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Adenomatous polyposis coli protein
  • Short names
    Protein APC

Gene names

    • Name
      Apc

Organism names

  • Taxonomic identifier
  • Strain
    • Fischer 344/N
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Rattus

Accessions

  • Primary accession
    P70478

Proteomes

Organism-specific databases

Subcellular Location

Cytoplasm
Cell membrane
Note: Associated with the microtubule network at the growing distal tip of microtubules. MAPRE1 may be required for targeting to the growing microtubule plus ends. Accumulates in the lamellipodium and ruffle membrane in response to hepatocyte growth factor (HGF) treatment. The MEMO1-RHOA-DIAPH1 signaling pathway controls localization of the phosphorylated form to the cell membrane.

Keywords

Phenotypes & Variants

Features

Showing features for mutagenesis.

TypeIDPosition(s)Description
Mutagenesis523In an IQ-induced colon tumor.

Keywords

PTM/Processing

Features

Showing features for initiator methionine, modified residue, chain.

TypeIDPosition(s)Description
Initiator methionine1Removed
Modified residue2N-acetylalanine
ChainPRO_00000646292-2842Adenomatous polyposis coli protein
Modified residue105Phosphoserine
Modified residue109Phosphoserine
Modified residue742Phosphoserine
Modified residue746Phosphoserine
Modified residue778Phosphoserine
Modified residue906Phosphoserine
Modified residue985Phosphoserine
Modified residue1036Phosphoserine
Modified residue1040Phosphoserine
Modified residue1357Phosphoserine
Modified residue1368Phosphoserine
Modified residue1382Phosphoserine
Modified residue1389Phosphoserine
Modified residue1392Phosphoserine
Modified residue1435Phosphothreonine
Modified residue1565Phosphoserine
Modified residue1714Phosphoserine
Modified residue1772Phosphoserine
Modified residue1859Phosphoserine
Modified residue1861Phosphoserine
Modified residue1862Phosphoserine
Modified residue1969Phosphoserine
Modified residue1971Phosphoserine
Modified residue2087Phosphoserine
Modified residue2092Phosphoserine
Modified residue2125Phosphoserine
Modified residue2129Phosphoserine
Modified residue2130Phosphoserine
Modified residue2132Phosphoserine
Modified residue2151Phosphothreonine
Modified residue2260Phosphoserine
Modified residue2270Phosphoserine
Modified residue2283Phosphoserine
Modified residue2473Phosphoserine
Modified residue2535Phosphoserine
Modified residue2569Phosphoserine
Modified residue2671Phosphoserine
Modified residue2674Phosphoserine
Modified residue2679Phosphothreonine
Modified residue2710Phosphoserine
Modified residue2723Phosphoserine
Modified residue2788Phosphoserine

Post-translational modification

Phosphorylated; phosphorylation enhances the F-actin bundling activity (By similarity).
Phosphorylated by GSK3B
Ubiquitinated, leading to its degradation by the proteasome. Ubiquitination is facilitated by Axin. Deubiquitinated by ZRANB1/TRABID (By similarity).

Keywords

Proteomic databases

PTM databases

Interaction

Subunit

Forms homooligomers (Probable). Found in a complex consisting of ARHGEF4, APC and CTNNB1 (By similarity).
Found in a complex composed of MACF1, APC, AXIN1, CTNNB1 and GSK3B (PubMed:16815997).
The complex composed, at least, of APC, CTNNB1 and GSK3B interacts with JPT1; the interaction requires the inactive form of GSK3B (phosphorylated at 'Ser-9') (By similarity).
Interacts with APC2 (By similarity).
Interacts with DLG1 (via PDZ domains) and DLG3 (via PDZ domains) (By similarity).
Interacts with alpha- and beta-catenins (By similarity).
Interacts with AXIN1 (via RGS domain) (By similarity).
Interacts with ARHGEF4 (via N-terminus) (By similarity).
Interacts (via C-terminal residues 2674-2843) with MAPRE1 (via C-terminal residues 206-211); the interaction inhibits association with and bundling of F-actin (By similarity).
Interacts with MAPRE2 and MAPRE3 (via C-terminus) (By similarity).
Interacts with DIAPH1; DIAPH1 acts as a scaffold protein for MAPRE1 and APC to stabilize microtubules and promote cell migration (By similarity).
Interacts with DIAPH2 (By similarity).
Interacts with SCRIB; may mediate APC targeting to adherens junctions of epithelial cells (By similarity).
Interacts with SPATA13 (via N-terminus and SH3 domain) (By similarity).
Interacts with ASAP1 (via SH3 domain) (By similarity).
Interacts (at the cell membrane) with AMER1 and AMER2 (via ARM repeats) (By similarity).
Interacts with KHDRBS1 (By similarity).
Interacts with actin; binds both to F-actin and actin filament bundles (By similarity).

Binary interactions

TypeEntry 1Entry 2Number of experimentsIntact
BINARY P70478Dlg4 P310162EBI-631663, EBI-375655

Protein-protein interaction databases

Structure

3D structure databases

Family & Domains

Features

Showing features for coiled coil, region, compositional bias, repeat, motif.

TypeIDPosition(s)Description
Coiled coil2-62
Coiled coil125-260
Region238-304Disordered
Compositional bias242-260Basic and acidic residues
Compositional bias264-281Polar residues
Compositional bias288-302Polar residues
Repeat451-493ARM 1
Repeat503-545ARM 2
Repeat546-589ARM 3
Repeat590-636ARM 4
Repeat637-681ARM 5
Repeat682-723ARM 6
Repeat724-765ARM 7
Region828-877Disordered
Compositional bias840-855Basic and acidic residues
Compositional bias860-877Polar residues
Region921-942Disordered
Compositional bias924-942Polar residues
Compositional bias956-973Polar residues
Region956-988Disordered
Region1018-1167Interaction with catenins
Region1058-1078Disordered
Compositional bias1064-1078Polar residues
Compositional bias1092-1128Polar residues
Region1092-1166Disordered
Compositional bias1130-1166Basic and acidic residues
Region1188-1249Disordered
Compositional bias1306-1339Polar residues
Region1306-1373Disordered
Compositional bias1354-1371Polar residues
Region1398-1474Disordered
Compositional bias1430-1447Pro residues
Region1525-1568Disordered
Compositional bias1543-1559Basic and acidic residues
Region1584-1609Disordered
Region1661-1711Disordered
Compositional bias1678-1698Basic and acidic residues
Region1748-1950Disordered
Compositional bias1785-1837Basic and acidic residues
Compositional bias1861-1893Basic and acidic residues
Region1864-1891Highly charged
Compositional bias1894-1916Polar residues
Compositional bias1963-1984Polar residues
Region1963-2010Disordered
Region2034-2058Interaction with AXIN1
Compositional bias2043-2061Basic and acidic residues
Region2043-2067Disordered
Region2148-2173Disordered
Compositional bias2155-2173Basic and acidic residues
Region2167-2674Basic region
Compositional bias2234-2249Polar residues
Region2234-2641Disordered
Compositional bias2261-2426Polar residues
Compositional bias2461-2499Polar residues
Region2475-2842Interaction with DLG1
Compositional bias2519-2533Basic and acidic residues
Compositional bias2557-2580Polar residues
Compositional bias2581-2596Basic and acidic residues
Compositional bias2617-2639Polar residues
Region2664-2842Disordered
Compositional bias2669-2686Polar residues
Region2674-2842Interaction with MAPRE1
Compositional bias2697-2730Polar residues
Compositional bias2756-2812Polar residues
Motif2802-2805Microtubule tip localization signal
Compositional bias2822-2842Polar residues
Motif2840-2842PDZ-binding

Domain

The microtubule tip localization signal (MtLS) motif; mediates interaction with MAPRE1 and targeting to the growing microtubule plus ends.
The basic region (residues 2167-2674) mediates the association with both microtubule and actin proteins and promotes the bundling of F-actin.

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    2,842
  • Mass (Da)
    310,533
  • Last updated
    1997-02-01 v1
  • Checksum
    3CBB2EA8A34E8F47
MAAASYDQLLKQVEALKMENSNLRQELEDNSNHLTELETEASNMKEVLKQLQGSIEDETMTSGQIDLLERLKEFNLDSNFPGVKLRSKMSLRSYGSREGSVSSRSGECSPVPMGSFPRRAFVNGSRESTGYLEELEKERSLLLADLDKEEKEKDWYYAQLQNLTKRIDSLPLTENFSLQTDMTRRQLEYEARQIRAAMEEQLGTCQDMEKRAQRRIARIQQIEKDILRVRQLLQSQAAEAERSSQSKHETASHEAERQLEGQGVAESNLATSGSGQSSAARVDHETAGVLSSSGTHSAPRRLTSHLGTKVEMVYSLLSMLGTHDKDDMSRTLLAMSSSQDSCISMRQSGCLPLLIQLLHGNDKDSVLLGNSRGSKEARARASAALHNIIHSQPDDKRGRREIRVLHLLEQIRAYCETCWEWQEAHEQGMDQDKNPMPAPVEHQICPAVCVLMKLSFDEEHRHAMNELGGLQAIAELLQVDCEMHGLTDDHYSVTLRRYAGMALTNLTFGDVANKATLCSMKGCMRALVAQLKSESEDLQQVIASVLRNLSWRADVNSKKTLREVGSVKALMECALEVKKESTLKSVLSALWNLSAHCTENKADICAVDGALAFLVGTLTYRSQTNTLAIIESGGGILRNVSSLIATNEDHRQILRENNCLQTLLQHLKSHSLTIVSNACGTLWNLSARNPKDQEALWDMGAVSMLKNLIHSKHKMIAMGSAAALRNLMANRPAKYKDANIMSPGSSLPSLHVRKQKALEAELDAQHLSETFDNIDNLSPKASHRSKQRHKQNLYGDYVFDASRHDDNRSDNFNTGNMTVLSPYLNTTVLPSSSSSRGSLDSSRSEKDRSLERERGIGLSTYHSATENPGTSSKRGLQLSATAAQIAKVMEEVSALHTSQDDRSPASAAELHCVAEERTAARRSSASHTHPNTHNFAKSESSNRTCSMPYAKVEYKRSSNDSLNSVTSSDGYGKRGQMKPSVESYSEDDEGKFCSYGQYPADLAHKIHSANHMDDNGGELDTPINYSLKYSDEQLNSGRQSPSQNERWARPKHVIEDEIKQNEQRQSRSQNTNFPVYSENTDDKHLKFQQHFGQQECVSPYRSRGTNGSETNRMGSSHAVNQNVNQSLCQEDDYEDDKPTNYSERYSEEEQHEEEERPTNYSIKYNEEKHHVDQPIDYSLKYATDISSSQKPSFSFSKTPSVQGTKTEHNSPSSEAASAPSSNAKRQSQLHPSSAQRNGQTPKGTACKVPSINQETMQTYCVEDTPICFSRCSSLSSLSSAEDEIGCDQTTQEADSANTLQIAEIKENDVTRSAQDPASDVPAVSQSTRTKPSRLQASGLASESARHKAVEFSSGAKSPSKSGAQTPKSPPEHYVQETPLVFSRCTSVSSLDSFESRSIASSVQSEPCSGMVSGIVSPSDLPDSPGQTMPPSRSKTPPPPPPPQPVQTKREVPKTKVPAAEQREGGPKQTAVSAAVQRVQVLPDADTLLHFATESTPDGFSCSSSLSALSLDEPFIQKDVELRIMPPVQENDNGNETEPEQPEESNENQDKEVEKPDSEKDLLDDSDDDDIEILEECIISAMPTKSSRKAKKLAQTASKLPPPVARKPSQLPVYKLLPSQSRLQAQKHVSFTPGDDVPRVYCVEGTPINFSTATSLSDLTIESPPNELAAGDGVRASVQSGEFEKRDTIPTEGRSTDEAQRGKVSSIAIPDLDGSKAEEGDILAECINSALPKGRSHKPFRVKKIMDQVQQASMTSSGTNKNQIDTKKKKPTSPVKPMPQNTEYRTRVRKNTDSKVNVNTEETFSDNKDSKKQSLKNNPKDLNDKLPDNEDRVRGGFTFDSPHHYAPIEGTPYCFSRNDSLSSLDFDDDDVDLSREKAELRKGKESKDSEAKVTCHTEPSSSQQSARKAQASTKHPVNRGPSKPLLQEQPTFPQSSKDVPDRGAATDEKLQNFAIENTPVCFSRNSSLSSLSDVDQENNNNEETGPVRDAEPANAQGQPGKPQASGYAPKSFHVEDTPVCFSRNSSLSSLSIDSEDDLLRECISSAMPKKRRPSRLKGEGEWQSPRKVGSVLAEDLTLDLKDIQRPESEHGLSPDSENFDWKAIQEGANSIVSSLHQAAAAAACLSRQASSDSDSILSLKSGVSLGSPFHLTPDQEEKPFTSHKGPRILKPGEKSTLEAKKIESENKGIKGGKKVYKSLITGKIRSNSEISSQMKQPLQTNMPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGPVATTSPRGTKPAVKSELSPITRQTSHISGSNKGPSRSGSRDSTPSRPTQQPLSRPMQSPGRNSISPGRNGISTPNKLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQLSQQNLSKQTGLSKNASSIPRSESASKGLNQMNNSNGSNKKVELSRMSSTKSSGSESDRSERPALVRQSTFIKEAPSPTLRRKLEESASFESLSPSSRPDSPTRSQAQTPVLSPSLPDMSLSTHPSVQAGGWRKLPPNLSPTIEYSDGRPSKRHDIARSHSESPSRLPVNRAGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESSEKAKSEDEKHVNSVPGPRQMKENQVPTKGTWRKIKESEISPTNTVSQTTSSGAASGAESKTLIYQMAPAVSRTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSISEKGNPSIKDSKDTQGKQSVGSGSPVQTVGLENRLNSFIQVEAPEQKGTETKAGQGSPAPVAETGETCMAERTPFSSSSSSKHSSPSGTVAARVTPFNYNPSPRKSSADSTSARPSQIPTPVGSSTKKRDSKTDSTESSGAQSPKRHSGSYLVTSV

Computationally mapped potential isoform sequences

There are 3 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A0A0G2K8G0A0A0G2K8G0_RATApc2860
G3V8Q9G3V8Q9_RATApc2842
A0A8I5ZR24A0A8I5ZR24_RATApc2825

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias242-260Basic and acidic residues
Compositional bias264-281Polar residues
Compositional bias288-302Polar residues
Compositional bias840-855Basic and acidic residues
Compositional bias860-877Polar residues
Compositional bias924-942Polar residues
Compositional bias956-973Polar residues
Compositional bias1064-1078Polar residues
Compositional bias1092-1128Polar residues
Compositional bias1130-1166Basic and acidic residues
Compositional bias1306-1339Polar residues
Compositional bias1354-1371Polar residues
Compositional bias1430-1447Pro residues
Compositional bias1543-1559Basic and acidic residues
Compositional bias1678-1698Basic and acidic residues
Compositional bias1785-1837Basic and acidic residues
Compositional bias1861-1893Basic and acidic residues
Compositional bias1894-1916Polar residues
Compositional bias1963-1984Polar residues
Compositional bias2043-2061Basic and acidic residues
Compositional bias2155-2173Basic and acidic residues
Compositional bias2234-2249Polar residues
Compositional bias2261-2426Polar residues
Compositional bias2461-2499Polar residues
Compositional bias2519-2533Basic and acidic residues
Compositional bias2557-2580Polar residues
Compositional bias2581-2596Basic and acidic residues
Compositional bias2617-2639Polar residues
Compositional bias2669-2686Polar residues
Compositional bias2697-2730Polar residues
Compositional bias2756-2812Polar residues
Compositional bias2822-2842Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
D38629
EMBL· GenBank· DDBJ
BAA07609.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

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