Timing and casting for actors of thymic negative selection.Dautigny N., Le Campion A., Lucas B.View abstractCategoriesFunctionSourceMGI: 88335PubMedEurope PMCJ Immunol 162:1294-1302 (1999)Mapped to77
Mice lacking the transcription factor CIITA--a second look.Williams G.S., Malin M., Vremec D., Chang C.H., Boyd R., Benoist C., Mathis D.View abstractCategoriesFunctionSourceMGI: 88335PubMedEurope PMCInt Immunol 10:1957-1967 (1998)Mapped to41
Altered thymic positive selection and intracellular signals in Cbl- deficient mice.Naramura M., Kole H.K., Hu R.J., Gu H.View abstractCategoriesFunctionSourceMGI: 88335PubMedEurope PMCProc Natl Acad Sci U S A 95:15547-15552 (1998)Mapped to15
The central role of CD4(+) T cells in the antitumor immune response.Hung K., Hayashi R., Lafond-Walker A., Lowenstein C., Pardoll D., Levitsky H.View abstractCategoriesFunctionSourceMGI: 88335PubMedEurope PMCJ Exp Med 188:2357-2368 (1998)Mapped to36
Visualization of CD4/CD8 T cell commitment.Chan S., Correia-Neves M., Dierich A., Benoist C., Mathis D.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 88335PubMedEurope PMCJ Exp Med 188:2321-2333 (1998)Mapped to31
Normal thymic selection of TCR transgenic CD4 T cells, but impaired survival in the periphery despite the presence of selecting MHC molecules.Barthlott T., Wright R.J., Stockinger B.View abstractCategoriesFunctionSourceMGI: 88335PubMedEurope PMCJ Immunol 161:3992-3999 (1998)Mapped to11
Thymic heterotypic cellular complexes in gene-targeted mice with defined blocks in T cell development and adhesion molecule expression.Oliveira-dos-Santos A.J., Penninger J.M., Rieker-Geley T., Matsumoto G., Mak T.M., Wick G.View abstractCategoriesFunctionSourceMGI: 88335PubMedEurope PMCEur J Immunol 28:2882-2892 (1998)Mapped to99+
CD4(+) and CD8(+) T cells make discrete contributions to demyelination and neurologic disease in a viral model of multiple sclerosis.Murray P.D., Pavelko K.D., Leibowitz J., Lin X., Rodriguez M.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 88335PubMedEurope PMCJ Virol 72:7320-7329 (1998)Mapped to12
CD4 regulation of TCR signaling and T cell differentiation following stimulation with peptides of different affinities for the TCR.Leitenberg D., Boutin Y., Constant S., Bottomly K.View abstractCategoriesFunctionSourceMGI: 88335PubMedEurope PMCJ Immunol 161:1194-1203 (1998)Mapped to4
CD4+ T cells migrate into inflamed skin only if they express ligands for E- and P-selectin.Tietz W., Allemand Y., Borges E., von Laer D., Hallmann R., Vestweber D., Hamann A.View abstractCategoriesFunctionSourceMGI: 88335PubMedEurope PMCJ Immunol 161:963-970 (1998)Mapped to12
Requirement of the CD8+ or CD4+ T lymphocyte subsets for the rejection of lymphoma and fibrosarcoma grafts studied in gene knockout hosts.Wen T., Trumper L., Fung-Leung W., Rahemtulla A., Klein E., Klein G., Mak T.W.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 88335PubMedEurope PMCImmunol Lett 61:187-190 (1998)Mapped to12
Theiler's virus infection of genetically susceptible mice induces central nervous system-infiltrating CTLs with no apparent viral or major myelin antigenic specificity.Lin X., Pease L.R., Murray P.D., Rodriguez M.View abstractCategoriesFunctionSourceMGI: 88335PubMedEurope PMCJ Immunol 160:5661-5668 (1998)Mapped to30
Enhanced lymphoproliferation and diminished autoimmunity in CD4-deficient MRL/lpr mice.Chesnutt M.S., Finck B.K., Killeen N., Connolly M.K., Goodman H., Wofsy D.View abstractCategoriesFunctionSourceMGI: 88335PubMedEurope PMCClin Immunol Immunopathol 87:23-32 (1998)Mapped to9
The level of CD4 surface protein influences T cell selection in the thymus.Frank G.D., Parnes J.R.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 88335PubMedEurope PMCJ Immunol 160:634-642 (1998)Mapped to7
Disruption of the CD4-major histocompatibility complex class II interaction blocks the development of CD4(+) T cells in vivo.Riberdy J.M., Mostaghel E., Doyle C.View abstractCategoriesFunctionSourceMGI: 88335PubMedEurope PMCProc Natl Acad Sci U S A 95:4493-4498 (1998)Mapped to4
CD4+ CD8+ thymocytes are preferentially induced to die following CD45 cross-linking, through a novel apoptotic pathway.Lesage S., Steff A.M., Philippoussis F., Page M., Trop S., Mateo V., Hugo P.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 88335PubMedEurope PMCJ Immunol 159:4762-4771 (1997)Mapped to40
The interferon regulatory transcription factor IRF-1 controls positive and negative selection of CD8+ thymocytes.Penninger J.M., Sirard C., Mittrucker H.W., Chidgey A., Kozieradzki I., Nghiem M., Hakem A., Kimura T., Timms E.[...], Mak T.W.View abstractCategoriesFunctionSourceMGI: 88335PubMedEurope PMCImmunity 7:243-254 (1997)Mapped to30
A spontaneously arising mutation in the DLAARN motif of murine ZAP-70 abrogates kinase activity and arrests thymocyte development.Wiest D.L., Ashe J.M., Howcroft T.K., Lee H.-M., Kemper D.M., Negishi I., Singer D.S., Singer A., Abe R.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 88335PubMedEurope PMCImmunity 6:663-671 (1997)Cited in1Mapped to61
CD1d1 mutant mice are deficient in natural T cells that promptly produce IL-4.Mendiratta S.K., Martin W.D., Hong S., Boesteanu A., Joyce S., Van Kaer L.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 88335PubMedEurope PMCImmunity 6:469-477 (1997)Mapped to81
Impairment of T cell development in deltaEF1 mutant mice.Higashi Y., Moribe H., Takagi T., Sekido R., Kawakami K., Kikutani H., Kondoh H.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 88335PubMedEurope PMCJ Exp Med 185:1467-1479 (1997)Mapped to27
Studies of the susceptibility of nude, CD4 knockout, and SCID mutant mice to the disease induced by the murine AIDS defective virus.Simard C., Klein S.J., Mak T., Jolicoeur P.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 88335PubMedEurope PMCJ Virol 71:3013-3022 (1997)Mapped to5
Murine psoriasis-like disorder induced by naive CD4+ T cells.Schon M.P., Detmar M., Parker C.M.View abstractCategoriesFunctionSourceMGI: 88335PubMedEurope PMCNat Med 3:183-188 (1997)Mapped to4
Replacement of pre-T cell receptor signaling functions by the CD4 coreceptor.Norment A.M., Forbush K.A., Nguyen N., Malissen M., Perlmutter R.M.View abstractCategoriesFunctionSourceMGI: 88335PubMedEurope PMCJ Exp Med 185:121-130 (1997)Mapped to4
Rapid commitment to negative selection of a thymocyte line independent of CD4 co-engagement.Kovalik J.P., Ansari B., Boothby M.View abstractCategoriesFunctionSourceMGI: 88335PubMedEurope PMCJ Immunol 157:5290-5299 (1996)Mapped to4
IL-10 inhibits lipopolysaccharide-induced murine B cell proliferation and cross-linking of surface antigen receptors or ligation of CD40 restores the response.Marcelletti J.F.View abstractCategoriesFunctionSourceMGI: 88335PubMedEurope PMCJ Immunol 157:3323-3333 (1996)Mapped to7