Timing and casting for actors of thymic negative selection.Dautigny N., Le Campion A., Lucas B.View abstractCategoriesFunctionSourceMGI: 88335PubMedEurope PMCJ Immunol 162:1294-1302 (1999)Mapped to77
Retinoic acid-induced thymic abnormalities in the mouse are associated with altered pharyngeal morphology, thymocyte maturation defects, and altered expression of Hoxa3 and Pax1.Mulder G.B., Manley N., Maggio-Price L.View abstractCategoriesExpressionSourceMGI: 88335PubMedEurope PMCTeratology 58:263-275 (1998)Mapped to35
Mice lacking the transcription factor CIITA--a second look.Williams G.S., Malin M., Vremec D., Chang C.H., Boyd R., Benoist C., Mathis D.View abstractCategoriesFunctionSourceMGI: 88335PubMedEurope PMCInt Immunol 10:1957-1967 (1998)Mapped to41
Altered thymic positive selection and intracellular signals in Cbl- deficient mice.Naramura M., Kole H.K., Hu R.J., Gu H.View abstractCategoriesFunctionSourceMGI: 88335PubMedEurope PMCProc Natl Acad Sci U S A 95:15547-15552 (1998)Mapped to15
The central role of CD4(+) T cells in the antitumor immune response.Hung K., Hayashi R., Lafond-Walker A., Lowenstein C., Pardoll D., Levitsky H.View abstractCategoriesFunctionSourceMGI: 88335PubMedEurope PMCJ Exp Med 188:2357-2368 (1998)Mapped to36
Visualization of CD4/CD8 T cell commitment.Chan S., Correia-Neves M., Dierich A., Benoist C., Mathis D.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 88335PubMedEurope PMCJ Exp Med 188:2321-2333 (1998)Mapped to31
BID, a proapoptotic BCL-2 family member, is localized to mouse chromosome 6 and human chromosome 22q11.Wang K., Yin X.M., Copeland N.G., Gilbert D.J., Jenkins N.A., Keck C.L., Zimonjic D.B., Popescu N.C., Korsmeyer S.J.View abstractCategoriesSequencesSourceMGI: 88335PubMedEurope PMCGenomics 53:235-238 (1998)Mapped to19
Normal thymic selection of TCR transgenic CD4 T cells, but impaired survival in the periphery despite the presence of selecting MHC molecules.Barthlott T., Wright R.J., Stockinger B.View abstractCategoriesFunctionSourceMGI: 88335PubMedEurope PMCJ Immunol 161:3992-3999 (1998)Mapped to11
Thymic heterotypic cellular complexes in gene-targeted mice with defined blocks in T cell development and adhesion molecule expression.Oliveira-dos-Santos A.J., Penninger J.M., Rieker-Geley T., Matsumoto G., Mak T.M., Wick G.View abstractCategoriesFunctionSourceMGI: 88335PubMedEurope PMCEur J Immunol 28:2882-2892 (1998)Mapped to99+
CD4(+) and CD8(+) T cells make discrete contributions to demyelination and neurologic disease in a viral model of multiple sclerosis.Murray P.D., Pavelko K.D., Leibowitz J., Lin X., Rodriguez M.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 88335PubMedEurope PMCJ Virol 72:7320-7329 (1998)Mapped to12
CD4 regulation of TCR signaling and T cell differentiation following stimulation with peptides of different affinities for the TCR.Leitenberg D., Boutin Y., Constant S., Bottomly K.View abstractCategoriesFunctionSourceMGI: 88335PubMedEurope PMCJ Immunol 161:1194-1203 (1998)Mapped to4
CD4+ T cells migrate into inflamed skin only if they express ligands for E- and P-selectin.Tietz W., Allemand Y., Borges E., von Laer D., Hallmann R., Vestweber D., Hamann A.View abstractCategoriesFunctionSourceMGI: 88335PubMedEurope PMCJ Immunol 161:963-970 (1998)Mapped to12
Cloning of a novel C-type lectin expressed by murine macrophages.Balch S.G., McKnight A.J., Seldin M.F., Gordon S.View abstractCategoriesSequencesSourceMGI: 88335PubMedEurope PMCJ. Biol. Chem. 273:18656-18664 (1998)Cited in1Mapped to10
Requirement of the CD8+ or CD4+ T lymphocyte subsets for the rejection of lymphoma and fibrosarcoma grafts studied in gene knockout hosts.Wen T., Trumper L., Fung-Leung W., Rahemtulla A., Klein E., Klein G., Mak T.W.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 88335PubMedEurope PMCImmunol Lett 61:187-190 (1998)Mapped to12
Theiler's virus infection of genetically susceptible mice induces central nervous system-infiltrating CTLs with no apparent viral or major myelin antigenic specificity.Lin X., Pease L.R., Murray P.D., Rodriguez M.View abstractCategoriesFunctionSourceMGI: 88335PubMedEurope PMCJ Immunol 160:5661-5668 (1998)Mapped to30
Enhanced lymphoproliferation and diminished autoimmunity in CD4-deficient MRL/lpr mice.Chesnutt M.S., Finck B.K., Killeen N., Connolly M.K., Goodman H., Wofsy D.View abstractCategoriesFunctionSourceMGI: 88335PubMedEurope PMCClin Immunol Immunopathol 87:23-32 (1998)Mapped to9
The level of CD4 surface protein influences T cell selection in the thymus.Frank G.D., Parnes J.R.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 88335PubMedEurope PMCJ Immunol 160:634-642 (1998)Mapped to7
Disruption of the CD4-major histocompatibility complex class II interaction blocks the development of CD4(+) T cells in vivo.Riberdy J.M., Mostaghel E., Doyle C.View abstractCategoriesFunctionSourceMGI: 88335PubMedEurope PMCProc Natl Acad Sci U S A 95:4493-4498 (1998)Mapped to4
Novel mutant mice secreting soluble CD4 without expression of membrane- bound CD4.Nagase H., Wang C.R., Yoshimoto T., Sugishita C., Shiroishi T., Matsuzawa A., Nariuchi H.View abstractCategoriesSequences, Phenotypes & VariantsSourceMGI: 88335PubMedEurope PMCEur J Immunol 28:403-412 (1998)Mapped to4
Comparative sequence analysis of a gene-rich cluster at human chromosome 12p13 and its syntenic region in mouse chromosome 6.Ansari-Lari M.A., Oeltjen J.C., Schwartz S., Zhang Z., Muzny D.M., Lu J., Gorrell J.H., Chinault A.C., Belmont J.W.[...], Gibbs R.A.View abstractCategoriesSequencesSourceMGI: 88335PubMedEurope PMCGenome Res. 8:29-40 (1998)Cited in14Mapped to43
A crucial role for B cells in neuroinvasive scrapie.Klein M.A., Frigg R., Flechsig E., Raeber A.J., Kalinke U., Bluethmann H., Bootz F., Suter M., Zinkernagel R.M., Aguzzi A.View abstractCategoriesSequences, Phenotypes & VariantsSourceMGI: 88335PubMedEurope PMCNature 390:687-690 (1997)Mapped to56
Comparative mapping of the human 22q11 chromosomal region and the orthologous region in mice reveals complex changes in gene organization.Puech A., Saint-Jore B., Funke B., Gilbert D.J., Sirotkin H., Copeland N.G., Jenkins N.A., Kucherlapati R., Morrow B., Skoultchi A.I.View abstractCategoriesSequencesSourceMGI: 88335PubMedEurope PMCProc Natl Acad Sci U S A 94:14608-14613 (1997)Mapped to99+
CD4+ CD8+ thymocytes are preferentially induced to die following CD45 cross-linking, through a novel apoptotic pathway.Lesage S., Steff A.M., Philippoussis F., Page M., Trop S., Mateo V., Hugo P.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 88335PubMedEurope PMCJ Immunol 159:4762-4771 (1997)Mapped to40
Mapping of six germ-cell-specific genes to mouse chromosomes.Matsui M., Ichihara H., Kobayashi S., Tanaka H., Tsuchida J., Nozaki M., Yoshimura Y., Nojima H., Rochelle J.M.[...], Seldin M.F.CategoriesSequencesSourceMGI: 88335PubMedEurope PMCMamm. Genome 8:873-874 (1997)Cited in1Mapped to62
The interferon regulatory transcription factor IRF-1 controls positive and negative selection of CD8+ thymocytes.Penninger J.M., Sirard C., Mittrucker H.W., Chidgey A., Kozieradzki I., Nghiem M., Hakem A., Kimura T., Timms E.[...], Mak T.W.View abstractCategoriesFunctionSourceMGI: 88335PubMedEurope PMCImmunity 7:243-254 (1997)Mapped to30