Requirement for Brn-3.0 in differentiation and survival of sensory and motor neurons.McEvilly R.J., Erkman L., Luo L., Sawchenko P.E., Ryan A.F., Rosenfeld M.G.View abstractCategoriesFunction, ExpressionSourceMGI: 2151253PubMedEurope PMCNature 384:574-577 (1996)Mapped to53
Docking protein 6 (DOK6) selectively docks the neurotrophic signaling transduction to restrain peripheral neuropathy.Guo Y., Xiang P., Sun X., Liu W., Zhou J., Yin B., Hou L., Qiang B., Li H.[...], Peng X.View abstractCategoryFunctionSourceMGI: 2151253PubMedEurope PMCSignal Transduct Target Ther 9:32-32 (2024)Mapped to99+
Loss of G9a does not phenocopy the requirement for Prdm12 in the development of the nociceptive neuron lineage.Tsimpos P., Desiderio S., Cabochette P., Poelvoorde P., Kricha S., Vanhamme L., Poulard C., Bellefroid E.J.View abstractCategoryFunctionSourceMGI: 2151253PubMedEurope PMCNeural Dev 19:1-1 (2024)Mapped to78
Mechanoreceptor signal convergence and transformation in the dorsal horn flexibly shape a diversity of outputs to the brain.Chirila A.M., Rankin G., Tseng S.Y., Emanuel A.J., Chavez-Martinez C.L., Zhang D., Harvey C.D., Ginty D.D.View abstractCategoryFunctionSourceMGI: 2151253PubMedEurope PMCCell 185:4541-4559.e23 (2022)Mapped to94
Lamin A/C-dependent chromatin architecture safeguards naive pluripotency to prevent aberrant cardiovascular cell fate and function.Wang Y., Elsherbiny A., Kessler L., Cordero J., Shi H., Serke H., Lityagina O., Trogisch F.A., Mohammadi M.M.[...], Dobreva G.View abstractCategoryFunctionSourceMGI: 2151253PubMedEurope PMCNat Commun 13:6663-6663 (2022)Mapped to93
Etv4 regulates nociception by controlling peptidergic sensory neuron development and peripheral tissue innervation.Rios A.S., De Vincenti A.P., Casadei M., Aquino J.B., Brumovsky P.R., Paratcha G., Ledda F.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 2151253PubMedEurope PMCDevelopment 149:dev200583-dev200583 (2022)Mapped to56
Meis1 Regulates Nociceptor Development and Behavioral Response to Tactile Stimuli.Cao Z., Huang C., Lu F., Jiang X., Hu Y., Cao C., Liu Z.View abstractCategoryFunctionSourceMGI: 2151253PubMedEurope PMCFront Mol Neurosci 15:901466-901466 (2022)Mapped to63
Peroxisome Metabolism Contributes to PIEZO2-Mediated Mechanical Allodynia.Gong Y., Laheji F., Berenson A., Qian A., Park S.O., Kok R., Selig M., Hahn R., Sadjadi R.[...], Eichler F.View abstractCategoryFunctionSourceMGI: 2151253PubMedEurope PMCCells 11:1842-1842 (2022)Mapped to84
A conserved YAP/Notch/REST network controls the neuroendocrine cell fate in the lungs.Shue Y.T., Drainas A.P., Li N.Y., Pearsall S.M., Morgan D., Sinnott-Armstrong N., Hipkins S.Q., Coles G.L., Lim J.S.[...], Sage J.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 2151253PubMedEurope PMCNat Commun 13:2690-2690 (2022)Mapped to63
Excess neuropeptides in lung signal through endothelial cells to impair gas exchange.Xu J., Xu L., Sui P., Chen J., Moya E.A., Hume P., Janssen W.J., Duran J.M., Thistlethwaite P.[...], Sun X.View abstractCategoryFunctionSourceMGI: 2151253PubMedEurope PMCDev Cell 57:839-853.e6 (2022)Mapped to89
PRMT7 targets of Foxm1 controls alveolar myofibroblast proliferation and differentiation during alveologenesis.He H., Chen J., Zhao J., Zhang P., Qiao Y., Wan H., Wang J., Mei M., Bao S., Li Q.View abstractCategoryFunctionSourceMGI: 2151253PubMedEurope PMCCell Death Dis 12:841-841 (2021)Mapped to96
Binary pan-cancer classes with distinct vulnerabilities defined by pro- or anti-cancer YAP/TEAD activity.Pearson J.D., Huang K., Pacal M., McCurdy S.R., Lu S., Aubry A., Yu T., Wadosky K.M., Zhang L.[...], Bremner R.View abstractCategoryFunctionSourceMGI: 2151253PubMedEurope PMCCancer Cell 39:1115-1134.e12 (2021)Mapped to54
Loss of Prdm12 during development, but not in mature nociceptors, causes defects in pain sensation.Landy M.A., Goyal M., Casey K.M., Liu C., Lai H.C.View abstractCategoriesFunction, ExpressionSourceMGI: 2151253PubMedEurope PMCCell Rep 34:108913-108913 (2021)Mapped to99+
Diversification of molecularly defined myenteric neuron classes revealed by single-cell RNA sequencing.Morarach K., Mikhailova A., Knoflach V., Memic F., Kumar R., Li W., Ernfors P., Marklund U.View abstractCategoriesFunction, ExpressionSourceMGI: 2151253PubMedEurope PMCNat Neurosci 24:34-46 (2021)Mapped to99+
Neurog2 Deficiency Uncovers a Critical Period of Cell Fate Plasticity and Vulnerability among Neural-Crest-Derived Somatosensory Progenitors.Venteo S., Desiderio S., Cabochette P., Deslys A., Carroll P., Pattyn A.View abstractCategoryFunctionSourceMGI: 2151253PubMedEurope PMCCell Rep 29:2953-2960.e2 (2019)Mapped to88
STK11 is required for the normal program of ciliated cell differentiation in airways.Chu Q., Yao C., Qi X., Stripp B.R., Tang N.View abstractCategoryFunctionSourceMGI: 2151253PubMedEurope PMCCell Discov 5:36-36 (2019)Mapped to99+
Lack of whey acidic protein (WAP) four-disulfide core domain protease inhibitor 2 (WFDC2) causes neonatal death from respiratory failure in mice.Nakajima K., Ono M., Radovic U., Dizdarevic S., Tomizawa S.I., Kuroha K., Nagamatsu G., Hoshi I., Matsunaga R.[...], Ohbo K.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 2151253PubMedEurope PMCDis Model Mech 12:dmm040139-dmm040139 (2019)Mapped to96
Diverse spinal commissural neuron populations revealed by fate mapping and molecular profiling using a novel Robo3<sup>Cre</sup> mouse.Tulloch A.J., Teo S., Carvajal B.V., Tessier-Lavigne M., Jaworski A.View abstractCategoriesFunction, ExpressionSourceMGI: 2151253PubMedEurope PMCJ Comp Neurol 527:2948-2972 (2019)Mapped to99+
Prdm12 Directs Nociceptive Sensory Neuron Development by Regulating the Expression of the NGF Receptor TrkA.Desiderio S., Vermeiren S., Van Campenhout C., Kricha S., Malki E., Richts S., Fletcher E.V., Vanwelden T., Schmidt B.Z.[...], Bellefroid E.J.View abstractCategoryFunctionSourceMGI: 2151253PubMedEurope PMCCell Rep 26:3522-3536.e5 (2019)Mapped to99+
PRDM12 Is Required for Initiation of the Nociceptive Neuron Lineage during Neurogenesis.Bartesaghi L., Wang Y., Fontanet P., Wanderoy S., Berger F., Wu H., Akkuratova N., Boucanova F., Medard J.J.[...], Chrast R.View abstractCategoriesFunction, ExpressionSourceMGI: 2151253PubMedEurope PMCCell Rep 26:3484-3492.e4 (2019)Mapped to86
Hippo signaling promotes lung epithelial lineage commitment by curbing Fgf10 and beta-catenin signaling.Volckaert T., Yuan T., Yuan J., Boateng E., Hopkins S., Zhang J.S., Thannickal V.J., Fassler R., De Langhe S.P.View abstractCategoryFunctionSourceMGI: 2151253PubMedEurope PMCDevelopment 146:dev166454-dev166454 (2019)Mapped to99+
Myh10 deficiency leads to defective extracellular matrix remodeling and pulmonary disease.Kim H.T., Yin W., Jin Y.J., Panza P., Gunawan F., Grohmann B., Buettner C., Sokol A.M., Preussner J.[...], Stainier D.Y.R.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 2151253PubMedEurope PMCNat Commun 9:4600-4600 (2018)Mapped to99+
Cellular Origin, Tumor Progression, and Pathogenic Mechanisms of Cutaneous Neurofibromas Revealed by Mice with <i>Nf1</i> Knockout in Boundary Cap Cells.Radomska K.J., Coulpier F., Gresset A., Schmitt A., Debbiche A., Lemoine S., Wolkenstein P., Vallat J.M., Charnay P., Topilko P.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 2151253PubMedEurope PMCCancer Discov 9:130-147 (2019)Mapped to99+
Histone arginine methylation by Prmt5 is required for lung branching morphogenesis through repression of BMP signaling.Li Q., Jiao J., Li H., Wan H., Zheng C., Cai J., Bao S.View abstractCategoryFunctionSourceMGI: 2151253PubMedEurope PMCJ Cell Sci 131:jcs217406-jcs217406 (2018)Mapped to99+
Roof Plate-Derived Radial Glial-like Cells Support Developmental Growth of Rapidly Adapting Mechanoreceptor Ascending Axons.Kridsada K., Niu J., Haldipur P., Wang Z., Ding L., Li J.J., Lindgren A.G., Herrera E., Thomas G.M.[...], Luo W.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 2151253PubMedEurope PMCCell Rep 23:2928-2941 (2018)Mapped to99+