P69345 · MTGA_NEIME

  • Protein
    Biosynthetic peptidoglycan transglycosylase
  • Gene
    mtgA
  • Status
    UniProtKB reviewed (Swiss-Prot)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    4/5

Function

function

Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

Catalytic activity

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentpeptidoglycan-based cell wall
Cellular Componentplasma membrane
Molecular Functionpentosyltransferase activity
Molecular Functionpeptidoglycan glycosyltransferase activity
Biological Processcell wall organization
Biological Processpeptidoglycan biosynthetic process
Biological Processregulation of cell shape

Keywords

Enzyme and pathway databases

Protein family/group databases

Names & Taxonomy

Protein names

  • Recommended name
    Biosynthetic peptidoglycan transglycosylase
  • EC number
  • Alternative names
    • Glycan polymerase
    • Peptidoglycan glycosyltransferase MtgA
      (PGT
      )

Gene names

    • Name
      mtgA
    • Synonyms
      mtg

Organism names

  • Taxonomic identifier
  • Strain
    • Allele 1 to allele 16
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Betaproteobacteria > Neisseriales > Neisseriaceae > Neisseria

Accessions

  • Primary accession
    P69345
  • Secondary accessions
    • O52423
    • O52424
    • O52425
    • O52426
    • O52427

Subcellular Location

Keywords

Phenotypes & Variants

Features

Showing features for natural variant.

TypeIDPosition(s)Description
Natural variant6in allele 2, allele 4, allele 7, allele 8, allele 12 and allele 15
Natural variant9in allele 15
Natural variant9in allele 1, allele 2, allele 4, allele 7, allele 8, allele 9, allele 10, allele 11, allele 12 and allele 16
Natural variant13in allele 1, allele 2, allele 4, allele 7, allele 8, allele 9, allele 10, allele 11, allele 12 and allele 16
Natural variant26in allele 4, allele 8, allele 12 and allele 15
Natural variant50in allele 10 and allele 15
Natural variant53in allele 15
Natural variant75in allele 15
Natural variant110in allele 15
Natural variant110in allele 7
Natural variant122-123in allele 15
Natural variant127in allele 15
Natural variant129in allele 7, allele 8, allele 9, allele 10, allele 11 and allele 14
Natural variant139in allele 16
Natural variant144in allele 13
Natural variant164in allele 5, allele 10, allele 13 and allele 15

Variants

We now provide the "Disease & Variants" viewer in its own tab.

The viewer provides 16 variants from UniProt as well as other sources including ClinVar and dbSNP.

Go to variant viewer

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00000831331-165Biosynthetic peptidoglycan transglycosylase

Structure

Family & Domains

Sequence similarities

Belongs to the glycosyltransferase 51 family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    165
  • Mass (Da)
    18,786
  • Last updated
    2005-03-01 v1
  • Checksum
    00A7B71CD976BE11
LDYRWMPYKRISTNLKKALIASEDARFAGHGGFDWGGIQNAIRRNRNSGKVKAGGSTISQQLAKNLFLNESRSYIRKGEEAAITAMMEAVTDKDRIFELYLNSIEWHYGVFGAEAASRYFYQIPAAKLTKQQAAKLTARVPAPLYYADHPKSKRLRNKTNIVLRR

Features

Showing features for non-terminal residue.

TypeIDPosition(s)Description
Non-terminal residue1
Non-terminal residue165

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AF037814
EMBL· GenBank· DDBJ
AAC08817.1
EMBL· GenBank· DDBJ
Genomic DNA
AF037815
EMBL· GenBank· DDBJ
AAC08818.1
EMBL· GenBank· DDBJ
Genomic DNA
AF037816
EMBL· GenBank· DDBJ
AAC08819.1
EMBL· GenBank· DDBJ
Genomic DNA
AF037817
EMBL· GenBank· DDBJ
AAC08820.1
EMBL· GenBank· DDBJ
Genomic DNA
AF037818
EMBL· GenBank· DDBJ
AAC08821.1
EMBL· GenBank· DDBJ
Genomic DNA
AF037819
EMBL· GenBank· DDBJ
AAC08822.1
EMBL· GenBank· DDBJ
Genomic DNA
AF037820
EMBL· GenBank· DDBJ
AAC08823.1
EMBL· GenBank· DDBJ
Genomic DNA
AF037821
EMBL· GenBank· DDBJ
AAC08824.1
EMBL· GenBank· DDBJ
Genomic DNA
AF037822
EMBL· GenBank· DDBJ
AAC08825.1
EMBL· GenBank· DDBJ
Genomic DNA
AF037823
EMBL· GenBank· DDBJ
AAC08826.1
EMBL· GenBank· DDBJ
Genomic DNA
AF037824
EMBL· GenBank· DDBJ
AAC08827.1
EMBL· GenBank· DDBJ
Genomic DNA
AF037825
EMBL· GenBank· DDBJ
AAC08828.1
EMBL· GenBank· DDBJ
Genomic DNA
AF037826
EMBL· GenBank· DDBJ
AAC08829.1
EMBL· GenBank· DDBJ
Genomic DNA
AF037827
EMBL· GenBank· DDBJ
AAC08830.1
EMBL· GenBank· DDBJ
Genomic DNA
AF037828
EMBL· GenBank· DDBJ
AAC08831.1
EMBL· GenBank· DDBJ
Genomic DNA
AF037829
EMBL· GenBank· DDBJ
AAC08832.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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