P68191 · SRA_ECOLI

  • Protein
    Stationary-phase-induced ribosome-associated protein
  • Gene
    sra
  • Status
    UniProtKB reviewed (Swiss-Prot)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    4/5

Function

function

Although this protein associates with the 30S subunit of the ribosome it is not considered to be a bona fide ribosomal protein.

Caution

Was originally thought to be a ribosomal protein.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytosol
Molecular Functionribosomal small subunit binding
Biological Processtranslation

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Stationary-phase-induced ribosome-associated protein
  • Short names
    Protein D; SRA
  • Alternative names
    • 30S ribosomal protein S22

Gene names

    • Name
      sra
    • Synonyms
      rpsV
    • Ordered locus names
      b1480, JW5962

Organism names

  • Taxonomic identifier
  • Strains
    • K12 / W3110 / ATCC 27325 / DSM 5911
    • K12
    • K12 / MG1655 / ATCC 47076
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Enterobacteriaceae > Escherichia

Accessions

  • Primary accession
    P68191
  • Secondary accessions
    • P28690
    • Q2MBA4

Proteomes

Subcellular Location

Cytoplasm
Note: Enriched in the periphery of the cell, excluded from the nucleoid (PubMed:21903814).

Keywords

Phenotypes & Variants

Disruption phenotype

Not essential, a quadruple raiA-hpf-rmf-sra knockout strain is significantly outcompeted by wild-type after 4 days growth (PubMed:17277072).

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00002086901-45Stationary-phase-induced ribosome-associated protein

Proteomic databases

Expression

Induction

Induced upon entry into stationary phase, this is controlled at least in part by the RpoS sigma factor.

Interaction

Subunit

Associates exclusively with the 30S subunit; there is 0.1 copy per ribosome in the exponential phase and 0.4 copies per ribosome in the stationary phase. This is also true for several other K12 derivatives and strain B/R.

Protein-protein interaction databases

Family & Domains

Features

Showing features for region.

TypeIDPosition(s)Description
Region21-45Disordered

Sequence similarities

Belongs to the SRA family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    45
  • Mass (Da)
    5,096
  • Last updated
    2004-10-25 v1
  • Checksum
    81DB6E2D2E222C2F
MKSNRQARHILGLDHKISNQRKIVTEGDKSSVVNNPTGRKRPAEK

Mass Spectrometry

Molecular mass is 5,095.9 Da. Determined by MALDI.

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
D13179
EMBL· GenBank· DDBJ
BAA02474.1
EMBL· GenBank· DDBJ
Genomic DNA
X55956
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
U00096
EMBL· GenBank· DDBJ
AAC74553.1
EMBL· GenBank· DDBJ
Genomic DNA
AP009048
EMBL· GenBank· DDBJ
BAE76452.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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