P63479 · ALR1_STAAM

Function

function

Catalyzes the interconversion of L-alanine and D-alanine.

Catalytic activity

Cofactor

pyridoxal 5'-phosphate (UniProtKB | Rhea| CHEBI:597326 )

Kinetics

KM SUBSTRATE pH TEMPERATURE[C] NOTES EVIDENCE
0.89 mMD-alanine30
2.77 mML-alanine30
Vmax pH TEMPERATURE[C] NOTES EVIDENCE
91 μmol/min/mg30toward D-alanine
250 μmol/min/mg30toward L-alanine

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1.

Features

Showing features for active site, binding site.

TypeIDPosition(s)Description
Active site39Proton acceptor; specific for D-alanine
Binding site138substrate
Active site265Proton acceptor; specific for L-alanine
Binding site312substrate

GO annotations

AspectTerm
Molecular Functionalanine racemase activity
Molecular Functionpyridoxal phosphate binding
Biological ProcessD-alanine biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Alanine racemase 1
  • EC number

Gene names

    • Name
      alr1
    • Synonyms
      alr
    • Ordered locus names
      SAV2070

Organism names

Accessions

  • Primary accession
    P63479
  • Secondary accessions
    • Q99SI5

Proteomes

PTM/Processing

Features

Showing features for chain, modified residue.

TypeIDPosition(s)Description
ChainPRO_00001145681-382Alanine racemase 1
Modified residue39N6-(pyridoxal phosphate)lysine

Interaction

Subunit

Homodimer.

Family & Domains

Sequence similarities

Belongs to the alanine racemase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    382
  • Mass (Da)
    42,809
  • Last updated
    2004-10-11 v1
  • Checksum
    A46B7E55F5A65E41
MSDKYYRSAYMNVDLNAVASNFKVFSTLHPNKTVMAVVKANAYGLGSVKVARHLMENGATFFAVATLDEAIELRMHGITAKILVLGVLPAKDIDKAIQHRVALTVPSKQWLKEAIKNISGEQEKKLWLHIKLDTGMGRLGIKDTNTYQEVIEIIQQYEQLVFEGVFTHFACADEPGDMTTEQYQRFKDMVNEAIKPEYIHCQNSAGSLLMDCQFCNAIRPGISLYGYYPSEYVQQKVKVHLKPSVQLIANVVQTKTLQAGESVSYGATYTATDPTTIALLPIGYADGYLRIMQGSFVNVNGHQCEVIGRVCMDQTIVKVPDQVKAGDSVILIDNHRESPQSVEVVAEKQHTINYEVLCNLSRRLPRIYHDGDQRFVTNELLK

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
BA000017
EMBL· GenBank· DDBJ
BAB58232.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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