P62678 · MTB_TREBE

Function

function

Metallothioneins have a high content of cysteine residues that bind various heavy metals.

Features

Showing features for binding site.

16051015202530354045505560
MDPCECSKSGTCNCGGSCTCTNCSCTSCKKSCCPCCPSGCTKCASGCVCKGKTCDTSCCQ
TypeIDPosition(s)Description
Binding site4a divalent metal cation 1 (UniProtKB | ChEBI); in cluster B
Binding site6a divalent metal cation 1 (UniProtKB | ChEBI); in cluster B
Binding site6a divalent metal cation 2 (UniProtKB | ChEBI); in cluster B
Binding site12a divalent metal cation 2 (UniProtKB | ChEBI); in cluster B
Binding site14a divalent metal cation 2 (UniProtKB | ChEBI); in cluster B
Binding site14a divalent metal cation 3 (UniProtKB | ChEBI); in cluster B
Binding site18a divalent metal cation 3 (UniProtKB | ChEBI); in cluster B
Binding site20a divalent metal cation 1 (UniProtKB | ChEBI); in cluster B
Binding site23a divalent metal cation 1 (UniProtKB | ChEBI); in cluster B
Binding site23a divalent metal cation 3 (UniProtKB | ChEBI); in cluster B
Binding site25a divalent metal cation 2 (UniProtKB | ChEBI); in cluster B
Binding site28a divalent metal cation 3 (UniProtKB | ChEBI); in cluster B
Binding site32a divalent metal cation 4 (UniProtKB | ChEBI); in cluster A
Binding site33a divalent metal cation 4 (UniProtKB | ChEBI); in cluster A
Binding site33a divalent metal cation 5 (UniProtKB | ChEBI); in cluster A
Binding site35a divalent metal cation 5 (UniProtKB | ChEBI); in cluster A
Binding site36a divalent metal cation 5 (UniProtKB | ChEBI); in cluster A
Binding site36a divalent metal cation 6 (UniProtKB | ChEBI); in cluster A
Binding site40a divalent metal cation 6 (UniProtKB | ChEBI); in cluster A
Binding site43a divalent metal cation 4 (UniProtKB | ChEBI); in cluster A
Binding site43a divalent metal cation 6 (UniProtKB | ChEBI); in cluster A
Binding site47a divalent metal cation 4 (UniProtKB | ChEBI); in cluster A
Binding site49a divalent metal cation 5 (UniProtKB | ChEBI); in cluster A
Binding site49a divalent metal cation 7 (UniProtKB | ChEBI); in cluster A
Binding site54a divalent metal cation 7 (UniProtKB | ChEBI); in cluster A
Binding site58a divalent metal cation 7 (UniProtKB | ChEBI); in cluster A
Binding site59a divalent metal cation 6 (UniProtKB | ChEBI); in cluster A
Binding site59a divalent metal cation 7 (UniProtKB | ChEBI); in cluster A

GO annotations

AspectTerm
Molecular Functionmetal ion binding

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Metallothionein B
  • Short names
    MT-B; MT-II

Gene names

    • Name
      mtb

Organism names

Accessions

  • Primary accession
    P62678
  • Secondary accessions
    • Q92145

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00001973011-60Metallothionein B

Structure

Family & Domains

Features

Showing features for region.

TypeIDPosition(s)Description
Region1-28Beta
Region29-60Alpha

Domain

Class I metallothioneins contain 2 metal-binding domains: four divalent ions are chelated within cluster A of the alpha domain and are coordinated via cysteinyl thiolate bridges to 11 cysteine ligands. Cluster B, the corresponding region within the beta domain, can ligate three divalent ions to 9 cysteines.

Sequence similarities

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    60
  • Mass (Da)
    5,992
  • Last updated
    2004-07-19 v1
  • Checksum
    E866F4AD61BC424A
MDPCECSKSGTCNCGGSCTCTNCSCTSCKKSCCPCCPSGCTKCASGCVCKGKTCDTSCCQ

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
Z72485
EMBL· GenBank· DDBJ
CAA96566.1
EMBL· GenBank· DDBJ
mRNA

Similar Proteins

Disclaimer

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