P62542 · HTF2_CARMO
- ProteinHypertrehalosaemic factor 2
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids
- Protein existenceEvidence at protein level
- Annotation score4/5
Function
function
Hypertrehalosaemic factors are neuropeptides that elevate the level of trehalose in the hemolymph (trehalose is the major carbohydrate in the hemolymph of insects).
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | extracellular region | |
Molecular Function | hormone activity | |
Biological Process | neuropeptide signaling pathway |
Keywords
- Molecular function
Names & Taxonomy
Protein names
- Recommended nameHypertrehalosaemic factor 2
- Alternative names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Polyneoptera > Phasmatodea > Verophasmatodea > Anareolatae > Lonchodidae > Lonchodinae > Carausius
Accessions
- Primary accessionP62542
- Secondary accessions
Subcellular Location
PTM/Processing
Features
Showing features for modified residue, peptide, glycosylation.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Modified residue | 1 | Pyrrolidone carboxylic acid | ||||
Sequence: Q | ||||||
Peptide | PRO_0000043429 | 1-10 | Hypertrehalosaemic factor 2 | |||
Sequence: QLTFTPNWGT | ||||||
Glycosylation | 8 | C-linked (Man) tryptophan; atypical | ||||
Sequence: W | ||||||
Modified residue | 10 | Threonine amide | ||||
Sequence: T |
Post-translational modification
The glycosylated tryptophan appears to be identical to the C-linked mannose found in mammals, but lacks the typical W-X-X-W motif. The carbohydrate moiety is not necessary for hypertrehalosaemic activity.
Keywords
- PTM