P62270 · RS18_MOUSE

  • Protein
    Small ribosomal subunit protein uS13
  • Gene
    Rps18
  • Status
    UniProtKB reviewed (Swiss-Prot)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    5/5

Function

function

Component of the small ribosomal subunit (PubMed:36517592).
The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:36517592).

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytoplasm
Cellular Componentcytosol
Cellular Componentcytosolic small ribosomal subunit
Cellular Componentnucleus
Cellular Componentpostsynapse
Cellular Componentpostsynaptic density
Cellular Componentribosome
Cellular Componentsmall ribosomal subunit
Cellular Componentsynapse
Molecular Functionprotein kinase binding
Molecular FunctionrRNA binding
Molecular Functionstructural constituent of ribosome
Biological Processcytoplasmic translation

Keywords

Enzyme and pathway databases

    • R-MMU-156827L13a-mediated translational silencing of Ceruloplasmin expression
    • R-MMU-1799339SRP-dependent cotranslational protein targeting to membrane
    • R-MMU-6791226Major pathway of rRNA processing in the nucleolus and cytosol
    • R-MMU-72649Translation initiation complex formation
    • R-MMU-72689Formation of a pool of free 40S subunits

Names & Taxonomy

Protein names

  • Recommended name
    Small ribosomal subunit protein uS13
  • Alternative names
    • 40S ribosomal protein S18
    • Ke-3 (Ke3)

Gene names

    • Name
      Rps18

Organism names

  • Taxonomic identifier
  • Strains
    • 129/SvJ
    • C57BL/6J
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus

Accessions

  • Primary accession
    P62270
  • Secondary accessions
    • P25232

Proteomes

Organism-specific databases

PTM/Processing

Features

Showing features for initiator methionine, modified residue, chain, cross-link.

TypeIDPosition(s)Description
Initiator methionine1Removed
Modified residue2N-acetylserine
ChainPRO_00001322132-152Small ribosomal subunit protein uS13
Cross-link91Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)
Modified residue94N6-acetyllysine; alternate
Cross-link94Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate
Modified residue106N6-acetyllysine; alternate
Cross-link106Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate

Keywords

Proteomic databases

PTM databases

Expression

Gene expression databases

Interaction

Subunit

Component of the small ribosomal subunit.

Binary interactions

TypeEntry 1Entry 2Number of experimentsIntact
BINARY P62270Casp3 P706775EBI-352460, EBI-1790419
BINARY P62270Casp7 P978644EBI-352460, EBI-5307197
View interactors in UniProtKB
View CPX-5261 in Complex Portal

Protein-protein interaction databases

Miscellaneous

Family & Domains

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    152
  • Mass (Da)
    17,719
  • Last updated
    2007-01-23 v3
  • Checksum
    4DAF0662C3F37F22
MSLVIPEKFQHILRVLNTNIDGRRKIAFAITAIKGVGRRYAHVVLRKADIDLTKRAGELTEDEVERVITIMQNPRQYKIPDWFLNRQKDVKDGKYSQVLANGLDNKLREDLERLKKIRAHRGLRHFWGLRVRGQHTKTTGRRGRTVGVSKKK

Computationally mapped potential isoform sequences

There are 2 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A0A3Q4EGP3A0A3Q4EGP3_MOUSERps1838
S4R1N6S4R1N6_MOUSERps18107

Features

Showing features for sequence conflict.

TypeIDPosition(s)Description
Sequence conflict104in Ref. 1; AAA16796

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
M76763
EMBL· GenBank· DDBJ
AAA16795.1
EMBL· GenBank· DDBJ
mRNA
M76762
EMBL· GenBank· DDBJ
AAA16796.1
EMBL· GenBank· DDBJ
Unassigned DNA
AF100956
EMBL· GenBank· DDBJ
AAC69898.1
EMBL· GenBank· DDBJ
Genomic DNA
AF110520
EMBL· GenBank· DDBJ
AAC97978.1
EMBL· GenBank· DDBJ
Genomic DNA
AK050626
EMBL· GenBank· DDBJ
BAC34350.1
EMBL· GenBank· DDBJ
mRNA
BC081459
EMBL· GenBank· DDBJ
AAH81459.1
EMBL· GenBank· DDBJ
mRNA
BC081458
EMBL· GenBank· DDBJ
AAH81458.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp