The human TAS2R16 receptor mediates bitter taste in response to beta- glucopyranosides.Bufe B., Hofmann T., Krautwurst D., Raguse J.-D., Meyerhof W.View abstractCited forNUCLEOTIDE SEQUENCE [GENOMIC DNA]CategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCNat. Genet. 32:397-401 (2002)Cited in14Mapped to15
Evolution of bitter taste receptors in humans and apes.Fischer A., Gilad Y., Man O., Paeaebo S.View abstractCited forNUCLEOTIDE SEQUENCE [GENOMIC DNA]CategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCMol. Biol. Evol. 22:432-436 (2005)Cited in99+12
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).The MGC Project TeamView abstractCited forNUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]CategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCGenome Res. 14:2121-2127 (2004)Cited in99+99+
Receptors for bitter and sweet taste.Montmayeur J.-P., Matsunami H.View abstractCited forREVIEWSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCCurr. Opin. Neurobiol. 12:366-371 (2002)Cited in41
Molecular mechanisms of bitter and sweet taste transduction.Margolskee R.F.Cited forREVIEWSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCJ. Biol. Chem. 277:1-4 (2002)Cited in41Mapped to7
Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways.Zhang Y., Hoon M.A., Chandrashekar J., Mueller K.L., Cook B., Wu D., Zuker C.S., Ryba N.J.View abstractCited forREVIEWSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCCell 112:293-301 (2003)Cited in41Mapped to14
Characterization and solubilization of bitter-responsive receptors that couple to gustducin.Ming D., Ruiz-Avila L., Margolskee R.F.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-3299609PubMedEurope PMCProc. Natl. Acad. Sci. U.S.A. 95:8933-8938 (1998)Cited in1Mapped to24
Transduction of bitter and sweet taste by gustducin.Wong G.T., Gannon K.S., Margolskee R.F.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-3299609PubMedEurope PMCNature 381:796-800 (1996)Cited in1Mapped to28
Amplification and kinetics of the activation steps in phototransduction.Pugh E.N. Jr., Lamb T.D.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-3299609PubMedEurope PMCBiochim Biophys Acta 1141:111-149 (1993)Mapped to33
Human taste cells express the G protein alpha-gustducin and neuron- specific enolase.Takami S., Getchell T.V., McLaughlin S.K., Margolskee R.F., Getchell M.L.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-3299609PubMedEurope PMCBrain Res. Mol. Brain Res. 22:193-203 (1994)Cited in1Mapped to99+
Photolyzed rhodopsin catalyzes the exchange of GTP for bound GDP in retinal rod outer segments.Kwok-Keung Fung B., Stryer L.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-3299609PubMedEurope PMCProc Natl Acad Sci U S A 77:2500-2504 (1980)Mapped to31
Flow of information in the light-triggered cyclic nucleotide cascade of vision.Fung B.K., Hurley J.B., Stryer L.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-3299609PubMedEurope PMCProc Natl Acad Sci U S A 78:152-156 (1981)Mapped to34
Effect of GTP on the rhodopsin-G-protein complex by transient formation of extra metarhodopsin II.Hofmann K.P.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-3299609PubMedEurope PMCBiochim Biophys Acta 810:278-281 (1985)Mapped to29
Presence of three distinct molecular species of Gi protein alpha subunit. Structure of rat cDNAs and human genomic DNAs.Itoh H., Toyama R., Kozasa T., Tsukamoto T., Matsuoka M., Kaziro Y.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-3299609PubMedEurope PMCJ. Biol. Chem. 263:6656-6664 (1988)Cited in4Mapped to99+
Nucleotide sequence for a cDNA encoding the alpha subunit of retinal transducin (GNAT1) isolated from the human eye.van Dop C., Medynski D.C., Apone L.M.AnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-3299609PubMedEurope PMCNucleic Acids Res. 17:4887-4887 (1989)Cited in1Mapped to99+
Alpha transducin is present in blue-, green-, and red-sensitive cone photoreceptors in the human retina.Lerea C.L., Bunt-Milam A.H., Hurley J.B.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-3299609PubMedEurope PMCNeuron 3:367-376 (1989)Cited in2Mapped to99+
The human bitter taste receptor hTAS2R39 is the primary receptor for the bitterness of theaflavins.Yamazaki T., Sagisaka M., Ikeda R., Nakamura T., Matsuda N., Ishii T., Nakayama T., Watanabe T.View abstractAnnotationhTAS2R39 is the primary receptor for the bitterness of theaflavinsCategoriesFunctionSourceGeneRif: 259285PubMedEurope PMCBiosci Biotechnol Biochem 78:1753-1756 (2014)Mapped to2
Major haplotypes of the human bitter taste receptor TAS2R41 encode functional receptors for chloramphenicol.Thalmann S., Behrens M., Meyerhof W.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-3299609PubMedEurope PMCBiochem Biophys Res Commun 435:267-273 (2013)Mapped to29
Soy isoflavones and other isoflavonoids activate the human bitter taste receptors hTAS2R14 and hTAS2R39.Roland W.S., Vincken J.P., Gouka R.J., van Buren L., Gruppen H., Smit G.View abstractAnnotationTAS2R14 and TAS2R39 were activated by isoflavones and other isoflavonoids.CategoriesFunctionSourceGeneRif: 259285PubMedEurope PMCJ Agric Food Chem 59:11764-11771 (2011)Mapped to4
Human bitter taste receptors hTAS2R8 and hTAS2R39 with differential functions to recognize bitter peptides.Ueno Y., Sakurai T., Okada S., Abe K., Misaka T.View abstractAnnotationHuman bitter taste receptors hTAS2R8 and hTAS2R39 display differential functions to recognize bitter peptides.CategoriesFunctionSourceGeneRif: 259285PubMedEurope PMCBiosci Biotechnol Biochem 75:1188-1190 (2011)Mapped to6
Evaluation of the bitterness of green tea catechins by a cell-based assay with the human bitter taste receptor hTAS2R39.Narukawa M., Noga C., Ueno Y., Sato T., Misaka T., Watanabe T.View abstractAnnotationthese results suggest the participation of hTAS2R39 in the detection of catechins in humans.CategoriesFunctionSourceGeneRif: 259285PubMedEurope PMCBiochem Biophys Res Commun 405:620-625 (2011)Mapped to2
The molecular receptive ranges of human TAS2R bitter taste receptors.Meyerhof W., Batram C., Kuhn C., Brockhoff A., Chudoba E., Bufe B., Appendino G., Behrens M.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-3299609PubMedEurope PMCChem Senses 35:157-170 (2010)Mapped to29
Dissociation of heterotrimeric g proteins in cells.Lambert N.A.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-3299609PubMedEurope PMCSci Signal 1:re5-re5 (2008)Mapped to99+
Role of the G-protein subunit alpha-gustducin in taste cell responses to bitter stimuli.Caicedo A., Pereira E., Margolskee R.F., Roper S.D.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-3299609PubMedEurope PMCJ. Neurosci. 23:9947-9952 (2003)Cited in1Mapped to28
Dominant loss of responsiveness to sweet and bitter compounds caused by a single mutation in alpha-gustducin.Ruiz-Avila L., Wong G.T., Damak S., Margolskee R.F.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-3299609PubMedEurope PMCProc. Natl. Acad. Sci. U.S.A. 98:8868-8873 (2001)Cited in2Mapped to28